HIBCH ELISA Kit for Human(Homo sapiens) | EIAab.comHIBCH ELISA Kit for Human(Homo sapiens)

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Index > Protein center > HIBCH(Gene name) > Human

HIBCH (Gene name),

3-hydroxyisobutyryl-CoA hydrolase, mitochondrial (Protein name ), HIBCH_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

HIBCH;

Protein name:

3-hydroxyisobutyryl-CoA hydrolase, mitochondrial;

Alternative:

3-hydroxyisobutyryl-coenzyme A hydrolase(HIB-CoA hydrolase;HIBYL-CoA-H);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA.

Subcellular Location:

Mitochondrion

Protein Attributes:

Sequence length:

386

Sequence:

50:

100:

150:

200:

250:

300:

350:

386:

IDKDQSPKWK | PADLKEVTEE | DLNNHFKSLG | SSDLKF

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

MIM:

250620

String:

Q6NVY1

STRING:

9606.ENSP00000352706

UniGene:

Hs.656685

Pfam:

PF00378

SMR:

Q6NVY1

KEGG:

hsa:26275

Uniprot:

Q6NVY1

FOR

ELISA Kit for Human 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial

CLIA Kit for Human 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial

Polyclonal Antibody for Human 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial

Monoclonal Antibody for Human 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial

Protein for Human 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Primary structure and tissue-specific expression of human beta-hydroxyisobutyryl-coenzyme A hydrolase."
Hawes J.W. , Jaskiewicz J. , Shimomura Y. , Huang B. , Bunting J. , Harper E.T. , Harris R.A.
J. Biol. Chem.271:26430-26434(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;CATALYTIC ACTIVITY;TISSUE SPECIFICITY
tissue: Brain.
2.

Suzuki Y. , Sugano S. , Totoki Y. , Toyoda A. , Takeda T. , Sakaki Y. , Tanaka A. , Yokoyama S.
Submitted (2005-04) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT ALA-46
tissue: Small intestine.
3.

"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];VARIANT ALA-46
5.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT ALA-46
tissue: Testis.
6.

"Lysine acetylation targets protein complexes and co-regulates major cellular functions."
Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-92;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
7.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
8.

"Crystal structure of human beta-hydroxyisobutyryl-COA hydrolase in complex with quercetin."
Structural genomics consortium (SGC)
Submitted (2008-01) to the PDB data bank

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.5 ANGSTROMS) OF 32-386 IN COMPLEX WITH 3-HYDROXY-2-METHYLPROPANOIC ACID AND QUERCETIN
9.

"Mutations in the gene encoding 3-hydroxyisobutyryl-CoA hydrolase results in progressive infantile neurodegeneration."
Loupatty F.J. , Clayton P.T. , Ruiter J.P.N. , Ofman R. , Ijlst L. , Brown G.K. , Thorburn D.R. , Harris R.A. , Duran M. , Desousa C. , Krywawych S. , Heales S.J.R. , Wanders R.J.A.
Am. J. Hum. Genet.80:195-199(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT HIBCHD CYS-122

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