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Index > Protein center > Hif1an(Gene name) > Mouse
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  • Hif1an (Gene name),
  • Hypoxia-inducible factor 1-alpha inhibitor (Protein name ),  HIF1N_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Hif1an;
    Protein name:
    Hypoxia-inducible factor 1-alpha inhibitor;
    Alternative:
    Hypoxia-inducible factor asparagine hydroxylase;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Homodimer. Interacts with VHL and HIF1A.
    Function:
    Hydroxylates HIF-1 alpha at 'Asp-799' in the C-terminal transactivation domain (CAD). Functions as an oxygen sensor and, under normoxic conditions, the hydroxylation prevents interaction of HIF-1 with transcriptional coactivators including Cbp/p300-interacting transactivator. Involved in transcriptional repression through interaction with HIF1A, VHL and histone deacetylases.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    349
    Sequence:
    50:
    MAATAAEVAA | SGSGEAREEA | EAPGPAWDES | QLRSYSFPTR | PIPRLSQSDP | 
    100:
    RAEELIENEE | PVVLTDTNLV | YPALKWDLEY | LQENIGNGDF | SVYSASTHKF | 
    150:
    LYYDEKKMGN | FQNFKPRSNR | EEIKFHEFVE | KLQAIQQRGG | EERLYLQQTL | 
    200:
    NDTVGRKIVM | DFLGFNWNWI | NKQQGKRGWG | QLTSNLLLIG | MEGNVTPAHY | 
    250:
    DEQQNFFAQI | KGHKRCILFP | PDQFECLYPY | PVHHPCDRQS | QVDFDNPDYE | 
    300:
    RFPNFRNVVG | YETVVGPGDV | LYIPMYWWHH | IESLLNGGIT | ITVNFWYKGA | 
    349:
    PTPKRIEYPL | KAHQKVAIMR | NIEKMLGEAL | GNPQEVGPLL | NTMIKGRYN
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    Pfam:
    String:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Hypoxia-inducible factor 1-alpha inhibitor
    Cat.:
    E0495h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse Hypoxia-inducible factor 1-alpha inhibitor
    Cat.:
    E0495m
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Hypoxia-inducible factor 1-alpha inhibitor
    Cat.:
    U0495m
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Hypoxia-inducible factor 1-alpha inhibitor
    Cat.:
    U0495h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Mouse Hypoxia-inducible factor 1-alpha inhibitor
    Cat.:
    P0495Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Hypoxia-inducible factor 1-alpha inhibitor
    Cat.:
    P0495Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Hypoxia-inducible factor 1-alpha inhibitor
    Monoclonal Antibody for Mouse Hypoxia-inducible factor 1-alpha inhibitor
    Protein for Mouse Hypoxia-inducible factor 1-alpha inhibitor
    Protein for Mouse Hypoxia-inducible factor 1-alpha inhibitor

    R&D Technical Data
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    Precision
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      strain: C57BL/6J.
      strain: NOD.
      tissue: Brain cortex.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    3. 3.
      "ASB4 is a hydroxylation substrate of FIH and promotes vascular differentiation via an oxygen-dependent mechanism."
      Ferguson J.E. III , Wu Y. , Smith K. , Charles P. , Powers K. , Wang H. , Patterson C.
      Mol. Cell. Biol.27:6407-6419(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH ASB4
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