HMGB1 ELISA Kit for Human(Homo sapiens) | EIAab.comHMGB1 ELISA Kit for Human(Homo sapiens)

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HMGB1 (Gene name),

High mobility group protein B1 (Protein name ), HMGB1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Citations (5)

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Gene name:

HMGB1(HMG1);

Protein name:

High mobility group protein B1;

Alternative:

High mobility group protein 1(HMG-1);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Component of the RAG complex composed of core components RAG1 and RAG2, and associated component HMGB1 or HMGB2.

Function:

DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells.

Subcellular Location:

Nucleus Chromosome

Protein Attributes:

Sequence length:

215

Sequence:

50:

100:

150:

200:

215:

EDEEDEDEEE | DDDDE

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF00505

String:

P09429

KEGG:

hsa:3146

STRING:

9606.ENSP00000343040

UniGene:

Hs.434102

SMR:

P09429

MIM:

163905

Uniprot:

P09429

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ELISA Kit for Human High mobility group protein B1

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E0399m

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96T

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ELISA Kit for Human High mobility group protein B1

MSDS:

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ELISA Kit for Human High mobility group protein B1

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E0399p

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96T

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ELISA Kit for Human High mobility group protein B1

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E0399r

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96T

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ELISA Kit for Human High mobility group protein B1

Cat.:

E0399h

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96T

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ELISA Kit for Human High mobility group protein B1

Cat.:

E0399d

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96T

ELISA Kit for Human High mobility group protein B1

Cat.:

E0399b

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96T

CLIA Kit for Human High mobility group protein B1

Cat.:

U0399c

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96T

CLIA Kit for Human High mobility group protein B1

Cat.:

U0399b

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96T

CLIA Kit for Human High mobility group protein B1

Cat.:

U0399d

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Packing:

96T

CLIA Kit for Human High mobility group protein B1

Cat.:

U0399p

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MSDS:

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Packing:

96T

CLIA Kit for Human High mobility group protein B1

Cat.:

U0399r

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MSDS:

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Packing:

96T

CLIA Kit for Human High mobility group protein B1

Cat.:

U0399h

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MSDS:

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Packing:

96T

CLIA Kit for Human High mobility group protein B1

Cat.:

U0399m

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Manual:

Looking for manual.

MSDS:

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96T

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Polyclonal Antibody for Human High mobility group protein B1

Cat.:

P0399Rb-h

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40ug/0.2ml

Polyclonal Antibody for Human High mobility group protein B1

Cat.:

P0399Rb-r

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40ug/0.2ml

Polyclonal Antibody for Human High mobility group protein B1

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P0399Rb-m

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40ug/0.2ml

Monoclonal Antibody for Human High mobility group protein B1

Protein for Human High mobility group protein B1

Cat.:

R0399b

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Packing:

1mg

Purity:

>90%

Protein for Human High mobility group protein B1

Cat.:

R0399d

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1mg

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>90%

Protein for Human High mobility group protein B1

Cat.:

R0399m

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1mg

Purity:

>90%

Protein for Human High mobility group protein B1

Cat.:

R0399p

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1mg

Purity:

>90%

Protein for Human High mobility group protein B1

Cat.:

R0399r

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Packing:

1mg

Purity:

>90%

Protein for Human High mobility group protein B1

Cat.:

R0399h

Price:

Please sign in first.

Packing:

1mg

Purity:

>90%

Protein for Human High mobility group protein B1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

12% SDS-PAGE analysis

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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Citations

[1].

"Assessment of HMGB-1 concentration in tick-borne encephalitis and neuroborreliosis"

P Penza, P Czupryna, O Zajkowska, et al.

From:International Journal of Infectious Diseases

[2].

"Is HMGB1 a New Indirect Marker for Revealing Fibrosis in Chronic Hepatitis and a New Therapeutic Target in Treatment?"

A Albayrak, MH Uyanik, S Cerrah, et al.

From:Viral Immunology

[3].

"Elevated serum levels of high mobility group box protein 1 (HMGB1) in patients with ankylosing spondylitis and its association with disease activity.."

P Oktayoglu, S Em, M Tahtasiz, et al.

From:Rheumatology International

[4].

"Effect of tumour necrosis factor-α inhibitor on serum level of dickkopf-1 protein and bone morphogenetic protein-7 in ankylosing spondylitis patients"

M Korkosz, J Gasowski, P Leszczynski

From:Scandinavian Journal of Rheumatology

[5].

"Resveratrol Does Not Benefit Patients with Non-alcoholic Fatty Liver Disease"

VS Chachay, GA Macdonald, JH Martin, et al.

From:Clinical Gastroenterology and Hepatology

References

1.

"A human placental cDNA clone that encodes nonhistone chromosomal protein HMG-1."
Wen L. , Huang J.K. , Johnson B.H. , Reeck G.R.
Nucleic Acids Res.17:1197-1214(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"The active gene that encodes human high mobility group 1 protein (HMG1) contains introns and maps to chromosome 13."
Ferrari S. , Finelli P. , Rocchi M. , Bianchi M.E.
Genomics35:367-371(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
3.

"Expression of high-mobility group-1 mRNA in human gastrointestinal adenocarcinoma and corresponding non-cancerous mucosa."
Xiang Y.-Y. , Wang D.-Y. , Tanaka M. , Suzuki M. , Kiyokawa E. , Igarashi H. , Niato Y. , Shen Q. , Sugimura H.
Int. J. Cancer74:1-6(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANTS ARG-11; GLU-149 AND GLY-190
4.

"The genetic variation of the human HMGB1 gene."
Kornblit B. , Munthe-Fog L. , Petersen S. , Madsen H. , Vindeloev L. , Garred P.
Tissue Antigens70:151-156(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
5.

He F.T. , Yang Z.H. , Ji Q. , Li R. , Peng J. , Jiang Y. , Zhong X.
Submitted (2003-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
6.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Cerebellum.
7.

"The full-ORF clone resource of the German cDNA consortium."
Bechtel S. , Rosenfelder H. , Duda A. , Schmidt C.P. , Ernst U. , Wellenreuther R. , Mehrle A. , Schuster C. , Bahr A. , Bloecker H. , Heubner D. , Hoerlein A. , Michel G. , Wedler H. , Koehrer K. , Ottenwaelder B. , Poustka A. , Wiemann S. , more...
BMC Genomics8:399-399(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Small intestine.
8.

"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
Submitted (2004-06) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
9.

"Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
Submitted (2004-10) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
10.

SeattleSNPs variation discovery resource
Submitted (2007-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT GLN-156
11.

"The DNA sequence and analysis of human chromosome 13."
Dunham A. , Matthews L.H. , Burton J. , Ashurst J.L. , Howe K.L. , Ashcroft K.J. , Beare D.M. , Burford D.C. , Hunt S.E. , Griffiths-Jones S. , Jones M.C. , Keenan S.J. , Oliver K. , Scott C.E. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Andrews D.T. , more...
Nature428:522-528(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
12.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
13.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Brain.
tissue: Cervix.
tissue: Testis.
14.

"Two-dimensional electrophoretic analysis of human breast carcinoma proteins: mapping of proteins that bind to the SH3 domain of mixed lineage kinase MLK2."
Rasmussen R.K. , Ji H. , Eddes J.S. , Moritz R.L. , Reid G.E. , Simpson R.J. , Dorow D.S.
Electrophoresis18:588-598(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 58-65 AND 113-127
tissue: Mammary carcinoma.
15.

"A quantitative atlas of mitotic phosphorylation."
Dephoure N. , Zhou C. , Villen J. , Beausoleil S.A. , Bakalarski C.E. , Elledge S.J. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-35 AND SER-100;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
16.

"Proteomic analysis of ubiquitinated proteins in normal hepatocyte cell line Chang liver cells."
Tan F. , Lu L. , Cai Y. , Wang J. , Xie Y. , Wang L. , Gong Y. , Xu B.-E. , Wu J. , Luo Y. , Qiang B. , Yuan J. , Sun X. , Peng X.
Proteomics8:2885-2896(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: UBIQUITINATION [LARGE SCALE ANALYSIS] AT LYS-112
tissue: Cervix carcinoma.
17.

"Lysine acetylation targets protein complexes and co-regulates major cellular functions."
Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-30;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
18.

"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-35;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
19.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
20.

"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-35;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
21.

"Novel role of PKR in inflammasome activation and HMGB1 release."
Lu B. , Nakamura T. , Inouye K. , Li J. , Tang Y. , Lundbaeck P. , Valdes-Ferrer S.I. , Olofsson P.S. , Kalb T. , Roth J. , Zou Y. , Erlandsson-Harris H. , Yang H. , Ting J.P. , Wang H. , Andersson U. , Antoine D.J. , Chavan S.S. , more...
Nature488:670-674(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION
22.

"Solution structure of the tandem HMG box domain from human high mobility group protein B1."
RIKEN structural genomics initiative (RSGI)
Submitted (2008-02) to the PDB data bank

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 1-166

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