Psmc3ip ELISA Kit for Rat(Rattus norvegicus) | EIAab.comPsmc3ip ELISA Kit for Rat(Rattus norvegicus)

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Index > Protein center > Psmc3ip(Gene name) > Rat

Psmc3ip (Gene name),

Homologous-pairing protein 2 homolog (Protein name ), HOP2_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Psmc3ip;

Protein name:

Homologous-pairing protein 2 homolog;

Alternative:

PSMC3-interacting protein;Nuclear receptor coactivator GT198;Proteasome 26S ATPase subunit 3-interacting protein;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Forms a stable heterodimer with MND1. Interacts with PSMC3/TBP1 (By similarity). Interacts with the DNA-binding domain of the nuclear receptors NR3C1/GR, ESR2/ER-beta, THRB and RXRA.

Function:

Plays an important role in meiotic recombination. Stimulates DMC1-mediated strand exchange required for pairing homologous chromosomes during meiosis. The complex PSMC3IP/MND1 binds DNA, stimulates the recombinase activity of DMC1 as well as DMC1 D-loop formation from double-strand DNA. This complex stabilizes presynaptic RAD51 and DMC1 filaments formed on single strand DNA to capture double-strand DNA. This complex stimulates both synaptic and presynaptic critical steps in RAD51 and DMC1-promoted homologous pairing. May inhibit HIV-1 viral protein TAT activity and modulate the activity of proteasomes through association with PSMC3 (By similarity). Plays a role as a coactivator in nuclear receptor-mediated transcription.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

217

Sequence:

50:

100:

150:

200:

217:

EVGIETDEDH | NVTLPNP

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF07106

UniGene:

Rn.144650

STRING:

10116.ENSRNOP00000027159

String:

Q91ZY6

KEGG:

rno:140938

Uniprot:

Q91ZY6

FOR

ELISA Kit for Rat Homologous-pairing protein 2 homolog

CLIA Kit for Rat Homologous-pairing protein 2 homolog

Polyclonal Antibody for Rat Homologous-pairing protein 2 homolog

Monoclonal Antibody for Rat Homologous-pairing protein 2 homolog

Protein for Rat Homologous-pairing protein 2 homolog

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Identification and characterization of a tissue-specific coactivator, GT198, that interacts with the DNA-binding domains of nuclear receptors."
Ko L. , Cardona G.R. , Henrion-Caude A. , Chin W.W.
Mol. Cell. Biol.22:357-369(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];INTERACTION WITH NR3C1; ESR2; THRB AND RXRA;REGION;PHOSPHORYLATION;FUNCTION
tissue: Pituitary.

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