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Index > Protein center > IL13RA1(Gene name) > Human
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  • IL13RA1 (Gene name),
  • Interleukin-13 receptor subunit alpha-1 (Protein name ),  I13R1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    IL13RA1(IL13R;IL13RA);
    Protein name:
    Interleukin-13 receptor subunit alpha-1(IL-13 receptor subunit alpha-1;IL-13R subunit alpha-1;IL-13R-alpha-1;IL-13RA1);
    Alternative:
    Cancer/testis antigen 19(CT19);
    CD:
    CD213a1;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interleukin-13 receptor is a complex of IL4R, IL13RA1, and possibly other components. Interacts with TRAF3IP1.
    Function:
    Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    427
    Sequence:
    50:
    MEWPARLCGL | WALLLCAGGG | GGGGGAAPTE | TQPPVTNLSV | SVENLCTVIW | 
    100:
    TWNPPEGASS | NCSLWYFSHF | GDKQDKKIAP | ETRRSIEVPL | NERICLQVGS | 
    150:
    QCSTNESEKP | SILVEKCISP | PEGDPESAVT | ELQCIWHNLS | YMKCSWLPGR | 
    200:
    NTSPDTNYTL | YYWHRSLEKI | HQCENIFREG | QYFGCSFDLT | KVKDSSFEQH | 
    250:
    SVQIMVKDNA | GKIKPSFNIV | PLTSRVKPDP | PHIKNLSFHN | DDLYVQWENP | 
    300:
    QNFISRCLFY | EVEVNNSQTE | THNVFYVQEA | KCENPEFERN | VENTSCFMVP | 
    350:
    GVLPDTLNTV | RIRVKTNKLC | YEDDKLWSNW | SQEMSIGKKR | NSTLYITMLL | 
    400:
    IVPVIVAGAI | IVLLLYLKRL | KIIIFPPIPD | PGKIFKEMFG | DQNDDTLHWK | 
    427:
    KYDIYEKQTK | EETDSVVLIE | NLKKASQ
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    MIM:
    String:
    KEGG:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human IL-13 receptor subunit alpha-1
    ELISA Kit for Human IL-13 receptor subunit alpha-1
    CLIA Kit for Human IL-13 receptor subunit alpha-1
    CLIA Kit for Human IL-13 receptor subunit alpha-1
    Polyclonal Antibody for Human IL-13 receptor subunit alpha-1
    Polyclonal Antibody for Human IL-13 receptor subunit alpha-1
    Monoclonal Antibody for Human IL-13 receptor subunit alpha-1
    Monoclonal Antibody for Human IL-13 receptor subunit alpha-1
    Protein for Human IL-13 receptor subunit alpha-1
    Protein for Human IL-13 receptor subunit alpha-1

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    Linearity
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    References
    1. 1.
      "Cloning of the human IL-13R alpha1 chain and reconstitution with the IL4R alpha of a functional IL-4/IL-13 receptor complex."
      Miloux B. , Laurent P. , Bonnin O. , Lupker J. , Caput D. , Vita N. , Ferrara P.
      FEBS Lett.401:163-166(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Carcinoma.
    2. 2.
      Gauchat J.-F. , Schlagenhauf E. , Feng N.P. , Moser R. , Yamage M. , Jeannin P. , Alouani S. , Elson G. , Notarangelo L.D. , Wells T. , Eugster H.P. , Bonnefoy J.-Y.
      Submitted (1997-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: B-cell.
    3. 3.
      "cDNA cloning and characterization of the human interleukin 13 receptor alpha chain."
      Aman M.J. , Tayebi N. , Obiri N.I. , Puri R.K. , Modi W.S. , Leonard W.J.
      J. Biol. Chem.271:29265-29270(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: T-cell.
    4. 4.
      Wada M. , Hisano T. , Kuwano M.
      Submitted (1999-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2)
    5. 5.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Hippocampus.
    6. 6.
      "The DNA sequence of the human X chromosome."
      Ross M.T. , Grafham D.V. , Coffey A.J. , Scherer S. , McLay K. , Muzny D. , Platzer M. , Howell G.R. , Burrows C. , Bird C.P. , Frankish A. , Lovell F.L. , Howe K.L. , Ashurst J.L. , Fulton R.S. , Sudbrak R. , Wen G. , Jones M.C. , more...
      Nature434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    8. 8.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Pancreas.
    9. 9.
      "MIP-T3, a novel protein linking tumor necrosis factor receptor-associated factor 3 to the microtubule network."
      Ling L. , Goeddel D.V.
      J. Biol. Chem.275:23852-23860(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TRAF3IP1
    10. 10.
      "Molecular and structural basis of cytokine receptor pleiotropy in the interleukin-4/13 system."
      LaPorte S.L. , Juo Z.S. , Vaclavikova J. , Colf L.A. , Qi X. , Heller N.M. , Keegan A.D. , Garcia K.C.
      Cell132:259-272(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF 29-342 IN COMPLEXES WITH IL4; IL4RA AND IL13;DISULFIDE BONDS;SUBUNIT
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