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Index > Protein center > Iapp(Gene name) > Rat
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  • Iapp (Gene name),
  • Islet amyloid polypeptide (Protein name ),  IAPP_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    Iapp;
    Protein name:
    Islet amyloid polypeptide;
    Alternative:
    Diabetes-associated peptide(DAP);Amylin;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Interacts with IDE and INS.
    Function:
    Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    93
    Sequence:
    50:
    MRCISRLPAV | LLILSVALGH | LRATPVGSGT | NPQVDKRKCN | TATCATQRLA | 
    93:
    NFLVRSSNNL | GPVLPPTNVG | SNTYGKRNVA | EDPNRESLDF | LLL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    Pfam:
    UniGene:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Islet amyloid polypeptide
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    E0812h
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    ELISA Kit for Rat Islet amyloid polypeptide
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    E0812r
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    ELISA Kit for Rat Islet amyloid polypeptide
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    ELISA Kit for Rat Islet amyloid polypeptide
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    ELISA Kit for Rat Islet amyloid polypeptide
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    E0812b
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    ELISA Kit for Rat Islet amyloid polypeptide
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    E0812d
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    ELISA Kit for Rat Islet amyloid polypeptide
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    CLIA Kit for Rat Islet amyloid polypeptide
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    U0812m
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    Packing:
    96T
    CLIA Kit for Rat Islet amyloid polypeptide
    MSDS:
    Please sign in first.
    CLIA Kit for Rat Islet amyloid polypeptide
    Cat.:
    U0812r
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    Packing:
    96T
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    CLIA Kit for Rat Islet amyloid polypeptide
    MSDS:
    Please sign in first.
    CLIA Kit for Rat Islet amyloid polypeptide
    Cat.:
    U0812h
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    Packing:
    96T
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    CLIA Kit for Rat Islet amyloid polypeptide
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    Packing:
    96T
    CLIA Kit for Rat Islet amyloid polypeptide
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    U0812d
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    Packing:
    96T
    Polyclonal Antibody for Rat Islet amyloid polypeptide
    Polyclonal Antibody for Rat Islet amyloid polypeptide
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    P0812Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Islet amyloid polypeptide
    Polyclonal Antibody for Rat Islet amyloid polypeptide
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    P0812Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Islet amyloid polypeptide
    Polyclonal Antibody for Rat Islet amyloid polypeptide
    Polyclonal Antibody for Rat Islet amyloid polypeptide
    Cat.:
    P0812Rb-r
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat Islet amyloid polypeptide
    Monoclonal Antibody for Rat Islet amyloid polypeptide
    Monoclonal Antibody for Rat Islet amyloid polypeptide
    Monoclonal Antibody for Rat Islet amyloid polypeptide
    Monoclonal Antibody for Rat Islet amyloid polypeptide
    Monoclonal Antibody for Rat Islet amyloid polypeptide
    Monoclonal Antibody for Rat Islet amyloid polypeptide
    Protein for Rat Islet amyloid polypeptide
    Protein for Rat Islet amyloid polypeptide
    Protein for Rat Islet amyloid polypeptide
    Protein for Rat Islet amyloid polypeptide
    Protein for Rat Islet amyloid polypeptide
    Protein for Rat Islet amyloid polypeptide
    Protein for Rat Islet amyloid polypeptide

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Conservation of the sequence of islet amyloid polypeptide in five mammals is consistent with its putative role as an islet hormone."
      Nishi M. , Chan S.J. , Nagamatsu S. , Bell G.I. , Steiner D.F.
      Proc. Natl. Acad. Sci. U.S.A.86:5738-5742(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Rat amylin: cloning and tissue-specific expression in pancreatic islets."
      Leffert J.D. , Newgard C.B. , Okamoto H. , Milburn J.L. , Luskey K.L.
      Proc. Natl. Acad. Sci. U.S.A.86:3127-3130(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "Islet amyloid polypeptide: structure and upstream sequences of the IAPP gene in rat and man."
      van Mansfeld A.D.M. , Mosselman S. , Hoeppener J.W.M. , Zandberg J. , van Teeffelen H.A.A.M. , Baas P.D. , Lips C.J.M. , Jansz H.S.
      Biochim. Biophys. Acta1087:235-240(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      strain: WAP.
      tissue: Liver.
    4. 4.
      "Isolation and sequence determination of rat islet amyloid polypeptide."
      Asai J. , Nakazato M. , Kangawa K. , Matsukura S. , Matsuo H.
      Biochem. Biophys. Res. Commun.164:400-405(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 38-74
    5. 5.
      "Regional distribution and molecular forms of rat islet amyloid polypeptide."
      Asai J. , Nakazato M. , Miyazato M. , Kangawa K. , Matsuo H. , Matsukura S.
      Biochem. Biophys. Res. Commun.169:788-795(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 38-74
    6. 6.
      "Sequence divergence in a specific region of islet amyloid polypeptide (IAPP) explains differences in islet amyloid formation between species."
      Betsholtz C. , Christmansson L. , Engstroem U. , Rorsman F. , Svensson V. , Johnson K.H. , Westermark P.
      FEBS Lett.251:261-264(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 38-74
    7. 7.
      "Amyloidogenesis abolished by proline substitutions but enhanced by lipid binding."
      Jiang P. , Xu W. , Mu Y.
      PLoS Comput. Biol.5:E1000357-E1000357(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DOMAIN
    8. 8.
      "Three-dimensional structure and orientation of rat islet amyloid polypeptide protein in a membrane environment by solution NMR spectroscopy."
      Nanga R.P. , Brender J.R. , Xu J. , Hartman K. , Subramanian V. , Ramamoorthy A.
      J. Am. Chem. Soc.131:8252-8261(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 38-74;DISULFIDE BOND
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