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Index > Protein center > ICAM3(Gene name) > Human
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  • ICAM3 (Gene name),
  • Intercellular adhesion molecule 3 (Protein name ),  ICAM3_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    ICAM3;
    Protein name:
    Intercellular adhesion molecule 3(ICAM-3);
    Alternative:
    ICAM-R;CDw50;
    CD:
    CD50;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM3 is also a ligand for integrin alpha-D/beta-2.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    547
    Sequence:
    50:
    MATMVPSVLW | PRACWTLLVC | CLLTPGVQGQ | EFLLRVEPQN | PVLSAGGSLF | 
    100:
    VNCSTDCPSS | EKIALETSLS | KELVASGMGW | AAFNLSNVTG | NSRILCSVYC | 
    150:
    NGSQITGSSN | ITVYRLPERV | ELAPLPPWQP | VGQNFTLRCQ | VEDGSPRTSL | 
    200:
    TVVLLRWEEE | LSRQPAVEEP | AEVTATVLAS | RDDHGAPFSC | RTELDMQPQG | 
    250:
    LGLFVNTSAP | RQLRTFVLPV | TPPRLVAPRF | LEVETSWPVD | CTLDGLFPAS | 
    300:
    EAQVYLALGD | QMLNATVMNH | GDTLTATATA | TARADQEGAR | EIVCNVTLGG | 
    350:
    ERREARENLT | VFSFLGPIVN | LSEPTAHEGS | TVTVSCMAGA | RVQVTLDGVP | 
    400:
    AAAPGQPAQL | QLNATESDDG | RSFFCSATLE | VDGEFLHRNS | SVQLRVLYGP | 
    450:
    KIDRATCPQH | LKWKDKTRHV | LQCQARGNPY | PELRCLKEGS | SREVPVGIPF | 
    500:
    FVNVTHNGTY | QCQASSSRGK | YTLVVVMDIE | AGSSHFVPVF | VAVLLTLGVV | 
    547:
    TIVLALMYVF | REHQRSGSYH | VREESTYLPL | TSMQPTEAMG | EEPSRAE
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    KEGG:
    Pfam:
    MIM:
    String:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human ICAM-3
    Cat.:
    E0533b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human ICAM-3
    Cat.:
    E0533h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human ICAM-3
    Cat.:
    U0533b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human ICAM-3
    Cat.:
    U0533h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human ICAM-3
    Polyclonal Antibody for Human ICAM-3
    Cat.:
    P0533Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human ICAM-3
    Monoclonal Antibody for Human ICAM-3
    Protein for Human ICAM-3
    Protein for Human ICAM-3

    R&D Technical Data
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    Precision
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Molecular cloning of ICAM-3, a third ligand for LFA-1, constitutively expressed on resting leukocytes."
      Fawcett J. , Holness C.L. , Needham L.A. , Turley H. , Gatter K.C. , Mason D.Y. , Simmons D.L.
      Nature360:481-484(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANTS AND GLY-115 GLY-143
    2. 2.
      "Cloning and characterization of a new intercellular adhesion molecule ICAM-R."
      Vazeux R. , Hoffman P.A. , Tomita J.K. , Dickinson E.S. , Jasman R.L. , St John T. , Gallatin W.M.
      Nature360:485-488(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANTS GLY-115 AND GLY-143
    3. 3.
      "Cloning and expression of intercellular adhesion molecule 3 reveals strong homology to other immunoglobulin family counter-receptors for lymphocyte function-associated antigen 1."
      de Fougerolles A.R. , Kilckstein L.B. , Springer T.A.
      J. Exp. Med.177:1187-1192(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANTS GLY-115 AND GLY-143
    4. 4.
      "Genetic variation in immune response genes."
      Tan J. , Ong R. , Hibberd M.L. , Seielstad M.
      Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Lung.
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 197-217; 269-293 AND 338-365
    8. 8.
      "Structural study of N-linked oligosaccharides of human intercellular adhesion molecule-3 (CD50)."
      Funatsu O. , Sato T. , Kotovuori P. , Gahmberg C.G. , Ikekita M. , Furukawa K.
      Eur. J. Biochem.268:1020-1029(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE OF N-LINKED CARBOHYDRATES
    9. 9.
      "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
      Liu T. , Qian W.-J. , Gritsenko M.A. , Camp D.G. II , Monroe M.E. , Moore R.J. , Smith R.D.
      J. Proteome Res.4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-206 AND ASN-363
      tissue: Plasma.
    10. 10.
      "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
      Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
      J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-206 AND ASN-363
      tissue: Liver.
    11. 11.
      "Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins."
      Wollscheid B. , Bausch-Fluck D. , Henderson C. , O'Brien R. , Bibel M. , Schiess R. , Aebersold R. , Watts J.D.
      Nat. Biotechnol.27:378-386(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-84; ASN-87; ASN-91; ASN-134; ASN-206; ASN-295 AND ASN-363
      tissue: Leukemic T-cell.
    12. 12.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    13. 13.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    14. 14.
      "An atomic resolution view of ICAM recognition in a complex between the binding domains of ICAM-3 and integrin alphaLbeta2."
      Song G. , Yang Y. , Liu J.-H. , Casasnovas J.M. , Shimaoka M. , Springer T.A. , Wang J.-H.
      Proc. Natl. Acad. Sci. U.S.A.102:3366-3371(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.66 ANGSTROMS) OF 30-115 IN COMPLEX WITH INTEGRIN ALPHALBETA2;DISULFIDE BOND;GLYCOSYLATION AT ASN-52 AND ASN-110
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