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Index > Protein center > EIF2S2(Gene name) > Rabbit
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  • EIF2S2 (Gene name),
  • Eukaryotic translation initiation factor 2 subunit 2 (Protein name ),  IF2B_RABIT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    EIF2S2(EIF2B);
    Protein name:
    Eukaryotic translation initiation factor 2 subunit 2;
    Alternative:
    Eukaryotic translation initiation factor 2 subunit beta(eIF-2-beta);
    Organism:
    Rabbit (Oryctolagus cuniculus). 
    General Annotation
    Sub Unit:
    Heterotrimer composed of an alpha, a beta and a gamma chain. Component of an EIF2 complex at least composed of CELF1/CUGBP1, CALR, CALR3, EIF2S1, EIF2S2, HSP90B1 and HSPA5.
    Function:
    eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    333
    Sequence:
    50:
    MSGDEMIFDP | TMSKKKKKKK | KPFMLDEEGD | AQTEETQPLE | TKEVEPEPTE | 
    100:
    DKDVEADEED | SRKKDASDDL | DDLNFFNQKK | KKKKTKKIFD | IDEAEEGVKD | 
    150:
    LKIENDVQEP | AEPEDDLDIM | LGNKKKKKKN | VKFPDEDEIL | EKDEALEDED | 
    200:
    SKKDDGISFS | NQTGPAWAGS | ERDYTYEELL | NRVFNIMREK | NPDMVAGEKR | 
    250:
    KFVMKPPQVV | RVGTKKTSFV | NFTDICKLLH | RQPKHLLAFL | LAELGTSGSI | 
    300:
    DGNNQLVIKG | RFQQKQIENV | LRRYIKEYVT | CHTCRSPDTI | LQKDTRLYFL | 
    333:
    QCETCHSRCS | VASIKTGFQA | VTGKRAQLRA | KAN
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Rabbit Eukaryotic translation initiation factor 2 subunit 2
    ELISA Kit for Rabbit Eukaryotic translation initiation factor 2 subunit 2
    ELISA Kit for Rabbit Eukaryotic translation initiation factor 2 subunit 2
    ELISA Kit for Rabbit Eukaryotic translation initiation factor 2 subunit 2
    CLIA Kit for Rabbit Eukaryotic translation initiation factor 2 subunit 2
    CLIA Kit for Rabbit Eukaryotic translation initiation factor 2 subunit 2
    CLIA Kit for Rabbit Eukaryotic translation initiation factor 2 subunit 2
    CLIA Kit for Rabbit Eukaryotic translation initiation factor 2 subunit 2
    Polyclonal Antibody for Rabbit Eukaryotic translation initiation factor 2 subunit 2
    Polyclonal Antibody for Rabbit Eukaryotic translation initiation factor 2 subunit 2
    Polyclonal Antibody for Rabbit Eukaryotic translation initiation factor 2 subunit 2
    Polyclonal Antibody for Rabbit Eukaryotic translation initiation factor 2 subunit 2
    Monoclonal Antibody for Rabbit Eukaryotic translation initiation factor 2 subunit 2
    Monoclonal Antibody for Rabbit Eukaryotic translation initiation factor 2 subunit 2
    Monoclonal Antibody for Rabbit Eukaryotic translation initiation factor 2 subunit 2
    Monoclonal Antibody for Rabbit Eukaryotic translation initiation factor 2 subunit 2
    Protein for Rabbit Eukaryotic translation initiation factor 2 subunit 2
    Protein for Rabbit Eukaryotic translation initiation factor 2 subunit 2
    Protein for Rabbit Eukaryotic translation initiation factor 2 subunit 2
    Protein for Rabbit Eukaryotic translation initiation factor 2 subunit 2

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Characterization of protein synthesis factors from rabbit reticulocytes."
      Merrick W.C. , Dever T.E. , Kinzy T.G. , Conroy S.C. , Cavallius J. , Owens C.L.
      Biochim. Biophys. Acta1050:235-240(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Cloning of cDNA for the beta-subunit of rabbit translation initiation factor-2 using PCR."
      Price N.T. , Hall L. , Proud C.G.
      Biochim. Biophys. Acta1216:170-172(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: New Zealand white.
    3. 3.
      "Amino acid sequence analysis of the beta- and gamma-subunits of eukaryotic initiation factor eIF-2. Identification of regions interacting with GTP."
      Bommer U.-A. , Kraft R. , Kurzchalia T.V. , Price N.T. , Proud C.G.
      Biochim. Biophys. Acta1079:308-315(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 25-39; 122-136 AND 195-218
      tissue: Reticulocyte.
    4. 4.
      "The purification and characterization of subunits alpha, beta, and gamma from the rabbit reticulocyte eukaryotic initiation factor 2."
      Schafer M.P. , Fairwell T. , Parker D.S. , Knight M. , Anderson W.F. , Safer B.
      Arch. Biochem. Biophys.255:337-346(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION
      tissue: Reticulocyte.
    5. 5.
      "Identification of novel phosphorylation sites in the beta-subunit of translation initiation factor eIF-2."
      Welsh G.I. , Price N.T. , Bladergroen B.A. , Bloomberg G. , Proud C.G.
      Biochem. Biophys. Res. Commun.201:1279-1288(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-2; SER-13; SER-67 AND SER-218
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