Gene name:
EIF4A1 (DDX2A;EIF4A) ;
Protein name:
Eukaryotic initiation factor 4A-I (eIF-4A-I;eIF4A-I) ;
Alternative:
ATP-dependent RNA helicase eIF4A-1 ;
Organism:
Rabbit (Oryctolagus cuniculus).
General Annotation
Sub Unit:
eIF4F is a multi-subunit complex, the composition of which varies with external and internal environmental conditions. It is composed of at least EIF4A, EIF4E and EIF4G1/EIF4G3. Interacts with PAIP1, EIF4E and UPF2. Found in a complex with XPO7, EIF4A1, ARHGAP1, VPS26A, VPS29, VPS35 and SFN. May interact with NOM1. Interacts with PDCD4; this interferes with the interaction between EIF4A and EIF4G. Interacts with RBM4.
Function:
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
Subcellular Location:
N/A
Protein Attributes:
50:
SRDNGPDGME | PEGVIESNWN | EIVDSFDDMN | LSESLLRGIY | AYGFEKPSAI |
100:
QQRAILPCIK | GYDVIAQAQS | GTGKTATFAI | SILQQIELDL | KATQALVLAP |
150:
TRELAQQIQK | VVMALGDYMG | ASCHACIGGT | NVRAEVQKLQ | MEAPHIIVGT |
200:
PGRVFDMLNR | RYLSPKYIKM | FVLDEADEML | SRGFKDQIYD | IFQKLNSNTQ |
250:
VVLLSATMPS | DVLEVTKKFM | RDPIRILVKK | EELTLEGIRQ | FYINVEREEW |
300:
KLDTLCDLYE | TLTITQAVIF | INTRRKVDWL | TEKMHARDFT | VSAMHGDMDQ |
350:
KERDVIMREF | RSGSSRVLIT | TDLLARGIDV | QQVSLVINYD | LPTNRENYIH |
398:
RIGRGGRFGR | KGVAINMVTE | EDKRTLRDIE | TFYNTSIEEM | PLNVADLI
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Rabbit
Human
Mouse
ELISA Kit for Rabbit eIF-4A-I
ELISA Kit for Rabbit eIF-4A-I
ELISA Kit for Rabbit eIF-4A-I
ELISA Kit for Rabbit eIF-4A-I
CLIA Kit for Rabbit eIF-4A-I
CLIA Kit for Rabbit eIF-4A-I
CLIA Kit for Rabbit eIF-4A-I
CLIA Kit for Rabbit eIF-4A-I
Polyclonal Antibody for Rabbit eIF-4A-I
Polyclonal Antibody for Rabbit eIF-4A-I
Polyclonal Antibody for Rabbit eIF-4A-I
Polyclonal Antibody for Rabbit eIF-4A-I
Monoclonal Antibody for Rabbit eIF-4A-I
Monoclonal Antibody for Rabbit eIF-4A-I
Monoclonal Antibody for Rabbit eIF-4A-I
Monoclonal Antibody for Rabbit eIF-4A-I
Protein for Rabbit eIF-4A-I
Protein for Rabbit eIF-4A-I
Protein for Rabbit eIF-4A-I
Protein for Rabbit eIF-4A-I
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
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Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 5-398;PARTIAL PROTEIN SEQUENCE