Gene name:
EIF4A2 (DDX2B;EIF4F) ;
Protein name:
Eukaryotic initiation factor 4A-II (eIF-4A-II;eIF4A-II) ;
Alternative:
ATP-dependent RNA helicase eIF4A-2 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
eIF4F is a multi-subunit complex, the composition of which varies with external and internal environmental conditions. It is composed of at least EIF4A, EIF4E and EIF4G1/EIFFG3 (By similarity). Interacts with EIF4E. May interact with NOM1. Interacts with HHV-1 Vhs.
Function:
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
Subcellular Location:
N/A
Protein Attributes:
50:
MSGGSADYNR | EHGGPEGMDP | DGVIESNWNE | IVDNFDDMNL | KESLLRGIYA |
100:
YGFEKPSAIQ | QRAIIPCIKG | YDVIAQAQSG | TGKTATFAIS | ILQQLEIEFK |
150:
ETQALVLAPT | RELAQQIQKV | ILALGDYMGA | TCHACIGGTN | VRNEMQKLQA |
200:
EAPHIVVGTP | GRVFDMLNRR | YLSPKWIKMF | VLDEADEMLS | RGFKDQIYEI |
250:
FQKLNTSIQV | VLLSATMPTD | VLEVTKKFMR | DPIRILVKKE | ELTLEGIKQF |
300:
YINVEREEWK | LDTLCDLYET | LTITQAVIFL | NTRRKVDWLT | EKMHARDFTV |
350:
SALHGDMDQK | ERDVIMREFR | SGSSRVLITT | DLLARGIDVQ | QVSLVINYDL |
400:
PTNRENYIHR | IGRGGRFGRK | GVAINFVTEE | DKRILRDIET | FYNTTVEEMP |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Bovine
Mouse
Rat
Chicken
ELISA Kit for Human eIF-4A-II
ELISA Kit for Human eIF-4A-II
ELISA Kit for Human eIF-4A-II
ELISA Kit for Human eIF-4A-II
ELISA Kit for Human eIF-4A-II
CLIA Kit for Human eIF-4A-II
CLIA Kit for Human eIF-4A-II
CLIA Kit for Human eIF-4A-II
CLIA Kit for Human eIF-4A-II
CLIA Kit for Human eIF-4A-II
Polyclonal Antibody for Human eIF-4A-II
Polyclonal Antibody for Human eIF-4A-II
Polyclonal Antibody for Human eIF-4A-II
Polyclonal Antibody for Human eIF-4A-II
Polyclonal Antibody for Human eIF-4A-II
Monoclonal Antibody for Human eIF-4A-II
Monoclonal Antibody for Human eIF-4A-II
Monoclonal Antibody for Human eIF-4A-II
Monoclonal Antibody for Human eIF-4A-II
Monoclonal Antibody for Human eIF-4A-II
Protein for Human eIF-4A-II
Protein for Human eIF-4A-II
Protein for Human eIF-4A-II
Protein for Human eIF-4A-II
Protein for Human eIF-4A-II
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
tissue :
Bone marrow .
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tissue :
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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