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Index > Protein center > IKZF3(Gene name) > Bovine
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  • IKZF3 (Gene name),
  • Zinc finger protein Aiolos (Protein name ),  IKZF3_BOVIN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    IKZF3(ZNFN1A3);
    Protein name:
    Zinc finger protein Aiolos;
    Alternative:
    Ikaros family zinc finger protein 3;
    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    Homodimer, and heterodimer with other IKAROS family members. Interacts with IKZF4 AND IKZF5. Interacts with IKZF1. Interacts with HRAS. Interacts with FOXP3; this interaction may be required for silencing target genes and regulating the suppressive activity of FOXP3-positive regulatory T-cells (Treg). Interacts with BCL21L; this interaction blocks the anti-apoptotic role of BCL21L. Associates with histone deacetylase complexes containing HDAC1, MTA2 and SIN3A.
    Function:
    Transcription factor that plays an important role in the regulation of lymphocyte differentiation. Plays an essential role in regulation of B-cell differentiation, proliferation and maturation to an effector state. Involved in regulating BCL2 expression and controlling apoptosis in T-cells in an IL2-dependent manner.
    Subcellular Location:
    Nucleus Cytoplasm
    Protein Attributes:
    Sequence length:
    509
    Sequence:
    50:
    MEDIKPNVEL | KSTQEQSVPT | EGSELLNDYD | LTKAHETENV | DGTEGPANED | 
    100:
    EDIGDDSMKV | KDEYSERDEN | VLKPEPMGNA | EEPEIPYSYS | REYNEYENIK | 
    150:
    LERHVVSYDS | SRPTSGKMNC | DVCGLSCISF | NVLMVHKRSH | TGERPFQCNQ | 
    200:
    CGASFTQKGN | LLRHIKLHTG | EKPFKCHLCN | YACQRRDALT | GHLRTHSVEK | 
    250:
    PYKCEFCGRS | YKQRSSLEEH | KERCRTFLQS | TDLGETASVE | ARHIKAEMGS | 
    300:
    ERALVLDRLA | SNVAKRKSSM | PQKFIGEKRH | CFDVSYNPSY | MYEKESEMIQ | 
    350:
    TRMMDQAINN | AISYLGAEAL | RPLVQTPPAP | TSEMVPVISS | MYPIALTRAE | 
    400:
    MPNGAPQELE | KKNIHLPEKS | LPSERGLSPT | NSGHDSTDTD | SNHEERQNHI | 
    450:
    YQQNPMVPPR | ARNGMPLLKE | GPRSYDLLKP | PPICPRDSIK | VINKEGEVTD | 
    500:
    VYRCDHCRVL | FLDYVMFTIH | MGCHGFRDPF | ECNMCGYRSH | DRYEFSSHIA | 
    509:
    RGEHRAMLK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Bovine Zinc finger protein Aiolos
    ELISA Kit for Bovine Zinc finger protein Aiolos
    ELISA Kit for Bovine Zinc finger protein Aiolos
    CLIA Kit for Bovine Zinc finger protein Aiolos
    CLIA Kit for Bovine Zinc finger protein Aiolos
    CLIA Kit for Bovine Zinc finger protein Aiolos
    Polyclonal Antibody for Bovine Zinc finger protein Aiolos
    Polyclonal Antibody for Bovine Zinc finger protein Aiolos
    Polyclonal Antibody for Bovine Zinc finger protein Aiolos
    Monoclonal Antibody for Bovine Zinc finger protein Aiolos
    Monoclonal Antibody for Bovine Zinc finger protein Aiolos
    Monoclonal Antibody for Bovine Zinc finger protein Aiolos
    Protein for Bovine Zinc finger protein Aiolos
    Protein for Bovine Zinc finger protein Aiolos
    Protein for Bovine Zinc finger protein Aiolos

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    Precision
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    Linearity
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    References
    1. 1.
      NIH - Mammalian Gene Collection (MGC) project
      Submitted (2007-02) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: Hereford.
      tissue: Thymus.
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