Gene name:
Ikzf4 (Zfpn1a4) ;
Protein name:
Zinc finger protein Eos ;
Alternative:
Ikaros family zinc finger protein 4 ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Self-associates. Interacts with other family members; IKZF1, IKZF2, IKZF3 AND IKZF5 (By similarity). Interacts with CTBP2, SPI1 and MITF.
Function:
DNA-binding protein that binds to the 5'GGGAATRCC-3' Ikaros-binding sequence. Interacts with SPI1 and MITF to repress transcription of the CTSK and ACP5 promoters via recruitment of corepressors SIN3A and CTBP2. May be involved in the development of central and peripheral nervous systems.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MHTPPALPRR | FQGGGRVRTP | GSHRQGKDNL | ERELSGGCAP | DFLPQAQDSN |
100:
HFIMESLFCE | SSGDSSLEKE | FLGAPVGPSV | STPNSQHSSP | SRSLSANSIK |
150:
VEMYSDEESS | RLLGPDERLL | DKDDSVIVED | SLSEPLGYCD | GSGPEPHSPG |
200:
GIRLPNGKLK | CDVCGMVCIG | PNVLMVHKRS | HTGERPFHCN | QCGASFTQKG |
250:
NLLRHIKLHS | GEKPFKCPFC | NYACRRRDAL | TGHLRTHSVS | SPTVGKPYKC |
300:
NYCGRSYKQQ | STLEEHKERC | HNYLQSLSTD | AQALTGQPGD | EIRDLEMVPD |
350:
SMLHPSTERP | TFIDRLANSL | TKRKRSTPQK | FVGEKQMRFS | LSDLPYDVNA |
400:
SGGYEKDVEL | VAHHGLEPGF | GGSLAFVGTE | HLRPLRLPPT | NCISELTPVI |
450:
SSVYTQMQPI | PSRLELPGSR | EAGEGPEDLG | DGGPLLYRAR | GSLTDPGASP |
500:
SNGCQDSTDT | ESNHEDRIGG | VVSLPQGPPP | QPPPTIVVGR | HSPAYAKEDP |
550:
KPQEGLLRGT | PGPSKEVLRV | VGESGEPVKA | FKCEHCRILF | LDHVMFTIHM |
586:
GCHGFRDPFE | CNICGYHSQD | RYEFSSHIVR | GEHKVG
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Mouse Zinc finger protein Eos
ELISA Kit for Mouse Zinc finger protein Eos
CLIA Kit for Mouse Zinc finger protein Eos
CLIA Kit for Mouse Zinc finger protein Eos
Polyclonal Antibody for Mouse Zinc finger protein Eos
Polyclonal Antibody for Mouse Zinc finger protein Eos
Monoclonal Antibody for Mouse Zinc finger protein Eos
Monoclonal Antibody for Mouse Zinc finger protein Eos
Protein for Mouse Zinc finger protein Eos
Protein for Mouse Zinc finger protein Eos
R&D Technical Data
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Precision
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Recovery
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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References
1.
"Eos: a novel member of the Ikaros gene family expressed predominantly in the developing nervous system."
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[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);FUNCTION;INTERACTION WITH IKZF1;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
strain :
ICR .
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"The transcriptional landscape of the mammalian genome."
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more...
Science309:1559-1563(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 3 AND 4)
strain :
NOD .
tissue :
Dendritic cell .
3.
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more...
PLoS Biol.7:E1000112-E1000112(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
C57BL/6J .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
tissue :
Brain .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH CTBP2
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;TISSUE SPECIFICITY;INTERACTION WITH SPI1 AND MITF