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Index > Protein center > Ikzf4(Gene name) > Mouse
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  • Ikzf4 (Gene name),
  • Zinc finger protein Eos (Protein name ),  IKZF4_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    Ikzf4(Zfpn1a4);
    Protein name:
    Zinc finger protein Eos;
    Alternative:
    Ikaros family zinc finger protein 4;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Self-associates. Interacts with other family members; IKZF1, IKZF2, IKZF3 AND IKZF5 (By similarity). Interacts with CTBP2, SPI1 and MITF.
    Function:
    DNA-binding protein that binds to the 5'GGGAATRCC-3' Ikaros-binding sequence. Interacts with SPI1 and MITF to repress transcription of the CTSK and ACP5 promoters via recruitment of corepressors SIN3A and CTBP2. May be involved in the development of central and peripheral nervous systems.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    586
    Sequence:
    50:
    MHTPPALPRR | FQGGGRVRTP | GSHRQGKDNL | ERELSGGCAP | DFLPQAQDSN | 
    100:
    HFIMESLFCE | SSGDSSLEKE | FLGAPVGPSV | STPNSQHSSP | SRSLSANSIK | 
    150:
    VEMYSDEESS | RLLGPDERLL | DKDDSVIVED | SLSEPLGYCD | GSGPEPHSPG | 
    200:
    GIRLPNGKLK | CDVCGMVCIG | PNVLMVHKRS | HTGERPFHCN | QCGASFTQKG | 
    250:
    NLLRHIKLHS | GEKPFKCPFC | NYACRRRDAL | TGHLRTHSVS | SPTVGKPYKC | 
    300:
    NYCGRSYKQQ | STLEEHKERC | HNYLQSLSTD | AQALTGQPGD | EIRDLEMVPD | 
    350:
    SMLHPSTERP | TFIDRLANSL | TKRKRSTPQK | FVGEKQMRFS | LSDLPYDVNA | 
    400:
    SGGYEKDVEL | VAHHGLEPGF | GGSLAFVGTE | HLRPLRLPPT | NCISELTPVI | 
    450:
    SSVYTQMQPI | PSRLELPGSR | EAGEGPEDLG | DGGPLLYRAR | GSLTDPGASP | 
    500:
    SNGCQDSTDT | ESNHEDRIGG | VVSLPQGPPP | QPPPTIVVGR | HSPAYAKEDP | 
    550:
    KPQEGLLRGT | PGPSKEVLRV | VGESGEPVKA | FKCEHCRILF | LDHVMFTIHM | 
    586:
    GCHGFRDPFE | CNICGYHSQD | RYEFSSHIVR | GEHKVG
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    KEGG:
    UniGene:
    SMR:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Zinc finger protein Eos
    ELISA Kit for Mouse Zinc finger protein Eos
    CLIA Kit for Mouse Zinc finger protein Eos
    CLIA Kit for Mouse Zinc finger protein Eos
    Polyclonal Antibody for Mouse Zinc finger protein Eos
    Polyclonal Antibody for Mouse Zinc finger protein Eos
    Monoclonal Antibody for Mouse Zinc finger protein Eos
    Monoclonal Antibody for Mouse Zinc finger protein Eos
    Protein for Mouse Zinc finger protein Eos
    Protein for Mouse Zinc finger protein Eos

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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Eos: a novel member of the Ikaros gene family expressed predominantly in the developing nervous system."
      Honma Y. , Kiyosawa H. , Mori T. , Oguri A. , Nikaido T. , Kanazawa K. , Tojo M. , Takeda J. , Tanno Y. , Yokoya S. , Kawabata I. , Ikeda H. , Wanaka A.
      FEBS Lett.447:76-80(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);FUNCTION;INTERACTION WITH IKZF1;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
      strain: ICR.
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 3 AND 4)
      strain: NOD.
      tissue: Dendritic cell.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Brain.
    5. 5.
      "The Ikaros family protein Eos associates with C-terminal-binding protein corepressors."
      Perdomo J. , Crossley M.
      Eur. J. Biochem.269:5885-5892(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CTBP2
    6. 6.
      "Eos, MITF, and PU.1 recruit corepressors to osteoclast-specific genes in committed myeloid progenitors."
      Hu R. , Sharma S.M. , Bronisz A. , Srinivasan R. , Sankar U. , Ostrowski M.C.
      Mol. Cell. Biol.27:4018-4027(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY;INTERACTION WITH SPI1 AND MITF
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