IL18 ELISA Kit for Human(Homo sapiens) | EIAab.comIL18 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > IL18(Gene name) > Human

IL18 (Gene name),

Interleukin-18 (Protein name ), IL18_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Citations (9)

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Gene name:

IL18(IGIF;IL1F4);

Protein name:

Interleukin-18(IL-18);

Alternative:

Interferon gamma-inducing factor(IFN-gamma-inducing factor);Iboctadekin;Interleukin-1 gamma(IL-1 gamma);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells.

Subcellular Location:

Secreted

Protein Attributes:

Sequence length:

193

Sequence:

50:

100:

150:

193:

FESSSYEGYF | LACEKERDLF | KLILKKEDEL | GDRSIMFTVQ | NED

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

hsa:3606

MIM:

600953

String:

Q14116

SMR:

Q14116

STRING:

9606.ENSP00000280357

Pfam:

PF00340

UniGene:

Hs.83077

Uniprot:

Q14116

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ELISA Kit for Human IL-18

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E0064h

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96T

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ELISA Kit for Human IL-18

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E0064r

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96T

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ELISA Kit for Human IL-18

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E0064m

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ELISA Kit for Human IL-18

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ELISA Kit for Human IL-18

Cat.:

E0064d

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ELISA Kit for Human IL-18

Cat.:

E0064b

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ELISA Kit for Human IL-18

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E0064c

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CLIA Kit for Human IL-18

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U0064b

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96T

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CLIA Kit for Human IL-18

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U0064d

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CLIA Kit for Human IL-18

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U0064p

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Looking for manual.

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Packing:

96T

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CLIA Kit for Human IL-18

Cat.:

U0064m

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Looking for manual.

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96T

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CLIA Kit for Human IL-18

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U0064r

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CLIA Kit for Human IL-18

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U0064h

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CLIA Kit for Human IL-18

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U0064c

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Polyclonal Antibody for Human IL-18

Cat.:

P0064Rb-r

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40ug/0.2ml

Polyclonal Antibody for Human IL-18

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P0064Rb-m

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Polyclonal Antibody for Human IL-18

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P0064Rb-h

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40ug/0.2ml

Monoclonal Antibody for Human IL-18

Protein for Human IL-18

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

Intra-Assay CV: ≤4.7%

Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

Inter-Assay CV: ≤7.1%

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

Recovery was determined by spiking various levels of IL-18 into serum and plasma .

Sample Type	Average(%)	Recovery Range(%)
Serum	102	96-106
Plasma	101	99-104

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

The linearity of the kit was assayed by testing samples spiked with appropriate concentration of IL-18 and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.

Sample	1：2	1:4	1:8	1:16
serum(n=5)	100-105%	94-101%	95-102%	92-97%
EDTA plasma(n=5)	90-95%	94-106%	105-107%	87-98%
heparin plasma(n=5)	95-103%	91-99%	104-107%	98-105%

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Citations

[1].

"High-dose dexamethasone regulates interleukin-18 and interleukin-18 binding protein in idiopathic thrombocytopenic purpura"

N Shan, X Zhu, Q Wang, et al.

From:haematologica

[2].

"Interleukin 18 and interleukin 18 binding protein in patients with idiopathic thrombocytopenic purpura"

N Shan, X Zhu, J Peng, et al.

From:British Journal of Haematology

[3].

"The imbalance of IL-18/IL-18BP in patients with systemic juvenile idiopathic arthritis"

O Chen, N Shan, X Zhu, et al

From:Acta Biochim Biophys Sin

[4].

"Будь ласка, використовуйте цей ідентифікатор, щоб цитувати або посилатися на цей матеріал"

Ащеулова Т.В., Аль Шейкх Диб Х. Х.

From:KhNMU Repository

[5].

"Imbalance of Interleukin-18 and Interleukin-18 Binding Protein in Children with Henoch-Schönlein Purpura"

YB Wang, NN Shan, O Chen, et al.

From:The Journal of International Medical Research

[6].

"КОМОРБІДНІ СТАНИ В КЛІНІЦІ ВНУТРІШНІХ ХВОРОБ"

В.М Лісовий, В.ВМ'ясоєдов, ГМ Кожина, et al.

From:Адреса редколегії

[7].

"Plasma Granzyme B in ST Elevation Myocardial Infarction versus Non-ST Elevation Acute Coronary Syndrome: Comparisons with IL-18 and Fractalkine"

HO El-Mesallamy, NM Hamdy, AK El-Etriby,et al.

From:Mediators of inflammation

[8].

"Ischemic stroke susceptibility gene in a Northern Han Chinese population"

H Wang, S Shi, W Yan, et al.

From:Neural Regeneration Research

[9].

"Будь ласка, використовуйте цей ідентифікатор, щоб цитувати або посилатися на цей матеріал"

ТВ Ащеулова, T Ashcheulova, ТВ Ащеулова, et al.

From:KhNMU Repository

References

1.

"Cloning of the cDNA for human IFN-gamma-inducing factor, expression in Escherichia coli, and studies on the biologic activities of the protein."
Ushio S. , Namba M. , Okura T. , Hattori K. , Nukada Y. , Akita K. , Tanabe F. , Konishi K. , Micallef M. , Fujii M. , Torigoe K. , Tanimoto T. , Fukuda S. , Ikeda M. , Okamura H. , Kurimoto M.
J. Immunol.156:4274-4279(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Liver.
2.

"A novel isoform of pro-interleukin-18 expressed in ovarian tumors is resistant to caspase-1 and -4 processing."
Gaggero A. , De Ambrosis A. , Mezzanzanica D. , Piazza T. , Rubartelli A. , Figini M. , Canevari S. , Ferrini S.
Oncogene23:7552-7560(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);PROTEOLYTIC PROCESSING;ALTERNATIVE SPLICING
3.

"Cloning and sequencing of the cDNA for precursor hIL-18."
Yong D. , Guixin D. , Lihua H. , Haitao W.
Submitted (1998-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
4.

"Cloning of human interleukin 18 cDNA."
Liu J. , Peng X. , Yuan J. , Qiang B.
Submitted (2001-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
5.

"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
Submitted (2004-06) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
6.

"Human chromosome 11 DNA sequence and analysis including novel gene identification."
Taylor T.D. , Noguchi H. , Totoki Y. , Toyoda A. , Kuroki Y. , Dewar K. , Lloyd C. , Itoh T. , Takeda T. , Kim D.-W. , She X. , Barlow K.F. , Bloom T. , Bruford E. , Chang J.L. , Cuomo C.A. , Eichler E. , FitzGerald M.G. , more...
Nature440:497-500(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
7.

Mural R.J. , Istrail S. , Sutton G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
8.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Urinary bladder.
9.

Conti B. , Kim S.J. , Tinti C. , Chun H.S. , Joh T.H.
Submitted (1997-02) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 2-193 (ISOFORM 1)
tissue: Peripheral blood.
10.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]

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