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Index > Protein center > Il1a(Gene name) > Mouse
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  • Il1a (Gene name),
  • Interleukin-1 alpha (Protein name ),  IL1A_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Il1a;
    Protein name:
    Interleukin-1 alpha(IL-1 alpha);
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Monomer.
    Function:
    Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
    Subcellular Location:
    Secreted The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.
    Protein Attributes:
    Sequence length:
    270
    Sequence:
    50:
    MAKVPDLFED | LKNCYSENED | YSSAIDHLSL | NQKSFYDASY | GSLHETCTDQ | 
    100:
    FVSLRTSETS | KMSNFTFKES | RVTVSATSSN | GKILKKRRLS | FSETFTEDDL | 
    150:
    QSITHDLEET | IQPRSAPYTY | QSDLRYKLMK | LVRQKFVMND | SLNQTIYQDV | 
    200:
    DKHYLSTTWL | NDLQQEVKFD | MYAYSSGGDD | SKYPVTLKIS | DSQLFVSAQG | 
    250:
    EDQPVLLKEL | PETPKLITGS | ETDLIFFWKS | INSKNYFTSA | AYPELFIATK | 
    270:
    EQSRVHLARG | LPSMTDFQIS | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    SMR:
    KEGG:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse IL-1 alpha
    Cat.:
    E0071h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse IL-1 alpha
    Cat.:
    E0071m
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse IL-1 alpha
    Cat.:
    E0071r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse IL-1 alpha
    Cat.:
    E0071p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse IL-1 alpha
    Cat.:
    E0071b
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse IL-1 alpha
    Cat.:
    E0071d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse IL-1 alpha
    Cat.:
    E0071g
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse IL-1 alpha
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse IL-1 alpha
    Cat.:
    U0071r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse IL-1 alpha
    Cat.:
    U0071h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse IL-1 alpha
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse IL-1 alpha
    Cat.:
    U0071b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse IL-1 alpha
    Cat.:
    U0071d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse IL-1 alpha
    Cat.:
    U0071m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse IL-1 alpha
    Cat.:
    U0071p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse IL-1 alpha
    Polyclonal Antibody for Mouse IL-1 alpha
    Cat.:
    P0071Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse IL-1 alpha
    Polyclonal Antibody for Mouse IL-1 alpha
    Cat.:
    P0071Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse IL-1 alpha
    Polyclonal Antibody for Mouse IL-1 alpha
    Polyclonal Antibody for Mouse IL-1 alpha
    Cat.:
    P0071Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse IL-1 alpha
    Monoclonal Antibody for Mouse IL-1 alpha
    Monoclonal Antibody for Mouse IL-1 alpha
    Monoclonal Antibody for Mouse IL-1 alpha
    Monoclonal Antibody for Mouse IL-1 alpha
    Monoclonal Antibody for Mouse IL-1 alpha
    Monoclonal Antibody for Mouse IL-1 alpha
    Protein for Mouse IL-1 alpha
    Protein for Mouse IL-1 alpha
    Protein for Mouse IL-1 alpha
    Protein for Mouse IL-1 alpha
    Protein for Mouse IL-1 alpha
    Protein for Mouse IL-1 alpha
    Protein for Mouse IL-1 alpha
    Cat.:
    R0071h
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%

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    References
    1. 1.
      "Cloning and expression of murine interleukin-1 cDNA in Escherichia coli."
      Lomedico P.T. , Gubler U. , Hellmann C.P. , Dukovich M. , Giri J.G. , Pan Y.-C.E. , Collier K. , Semionow R. , Chua A.O. , Mizel S.B.
      Nature312:458-462(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Complete nucleotide sequence of the murine interleukin-1 alpha gene."
      Kastelic T. , Wanner A. , Mackenzie A. , Cheneval D.
      Submitted (1997-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      strain: BALB/c.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: FVB/N.
      tissue: Mammary gland.
    4. 4.
      "The precursor of interleukin-1 alpha is phosphorylated at residue serine 90."
      Beuscher H.U. , Nickells M.W. , Colten H.R.
      J. Biol. Chem.263:4023-4028(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-90
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