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Index > Protein center > Il1r1(Gene name) > Mouse
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  • Il1r1 (Gene name),
  • Interleukin-1 receptor type 1 (Protein name ),  IL1R1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Il1r1(Il-1r1;Il1ra);
    Protein name:
    Interleukin-1 receptor type 1(IL-1R-1;IL-1RT-1;IL-1RT1);
    Alternative:
    Interleukin-1 receptor alpha(IL-1R-alpha);CD121 antigen-like family member A;p80;Interleukin-1 receptor type I;
    CD:
    CD121a;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Binds IL1RAP.
    Function:
    Receptor for interleukin-1 alpha (IL-1A), beta (IL-1B), and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappa-B. Signaling involves formation of a ternary complex containing IL1RAP, TOLLIP, MYD88, and IRAK1 or IRAK2.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    576
    Sequence:
    50:
    MENMKVLLGL | ICLMVPLLSL | EIDVCTEYPN | QIVLFLSVNE | IDIRKCPLTP | 
    100:
    NKMHGDTIIW | YKNDSKTPIS | ADRDSRIHQQ | NEHLWFVPAK | VEDSGYYYCI | 
    150:
    VRNSTYCLKT | KVTVTVLEND | PGLCYSTQAT | FPQRLHIAGD | GSLVCPYVSY | 
    200:
    FKDENNELPE | VQWYKNCKPL | LLDNVSFFGV | KDKLLVRNVA | EEHRGDYICR | 
    250:
    MSYTFRGKQY | PVTRVIQFIT | IDENKRDRPV | ILSPRNETIE | ADPGSMIQLI | 
    300:
    CNVTGQFSDL | VYWKWNGSEI | EWNDPFLAED | YQFVEHPSTK | RKYTLITTLN | 
    350:
    ISEVKSQFYR | YPFICVVKNT | NIFESAHVQL | IYPVPDFKNY | LIGGFIILTA | 
    400:
    TIVCCVCIYK | VFKVDIVLWY | RDSCSGFLPS | KASDGKTYDA | YILYPKTLGE | 
    450:
    GSFSDLDTFV | FKLLPEVLEG | QFGYKLFIYG | RDDYVGEDTI | EVTNENVKKS | 
    500:
    RRLIIILVRD | MGGFSWLGQS | SEEQIAIYNA | LIQEGIKIVL | LELEKIQDYE | 
    550:
    KMPDSIQFIK | QKHGVICWSG | DFQERPQSAK | TRFWKNLRYQ | MPAQRRSPLS | 
    576:
    KHRLLTLDPV | RDTKEKLPAA | THLPLG
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    String:
    KEGG:
    SMR:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse IL-1R-1
    Cat.:
    E0065h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse IL-1R-1
    Cat.:
    E0065m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse IL-1R-1
    Cat.:
    E0065r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse IL-1R-1
    Cat.:
    U0065m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse IL-1R-1
    Cat.:
    U0065r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse IL-1R-1
    Cat.:
    U0065h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Mouse IL-1R-1
    Cat.:
    P0065Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse IL-1R-1
    Cat.:
    P0065Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse IL-1R-1
    Cat.:
    P0065Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse IL-1R-1
    Monoclonal Antibody for Mouse IL-1R-1
    Monoclonal Antibody for Mouse IL-1R-1
    Protein for Mouse IL-1R-1
    Protein for Mouse IL-1R-1
    Protein for Mouse IL-1R-1

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "cDNA expression cloning of the IL-1 receptor, a member of the immunoglobulin superfamily."
      Sims J.E. , March C.J. , Cosman D. , Widmer M.B. , McDonald H.R. , McMahan C.J. , Grubin C.E. , Wignall J.M. , Jackson J.L. , Call S.M. , Friend D. , Alpert A.R. , Gillis S. , Urdal D.L. , Dower S.K.
      Science241:585-589(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 20-45
    2. 2.
      "Phorbol ester induces phosphorylation of the 80 kilodalton murine interleukin 1 receptor at a single threonine residue."
      Bird T.A. , Woodward A. , Jackson J.L. , Dower S.K. , Sims J.E.
      Biochem. Biophys. Res. Commun.177:61-67(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT THR-556
    3. 3.
      "Molecular cloning and characterization of a second subunit of the interleukin 1 receptor complex."
      Greenfeder S.A. , Nunes P. , Kwee L. , Labow M. , Chizzonite R.A. , Ju G.
      J. Biol. Chem.270:13757-13765(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH IL1RAP
    4. 4.
      "Tollip, a new component of the IL-1R1 pathway, links IRAK to the IL-1 receptor."
      Burns K. , Clatworthy J. , Martin L. , Martinon F. , Plumpton C. , Maschera B. , Lewis A. , Ray K. , Tschopp J. , Volpe F.
      Nat. Cell Biol.2:346-351(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TOLLIP; MYD88 AND IRAK1
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: 3D-STRUCTURE MODELING OF 25-334
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