Protein name:
Interleukin-1 receptor type 1 (IL-1R-1;IL-1RT-1;IL-1RT1) ;
Alternative:
Interleukin-1 receptor alpha (IL-1R-alpha) ;CD121 antigen-like family member A ;p80 ;Interleukin-1 receptor type I ;
CD:
CD121a ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Function:
Receptor for interleukin-1 alpha (IL-1A), beta (IL-1B), and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappa-B. Signaling involves formation of a ternary complex containing IL1RAP, TOLLIP, MYD88, and IRAK1 or IRAK2.
Subcellular Location:
Membrane
Single-pass type I membrane protein
Protein Attributes:
50:
MENMKVLLGF | ICLIVPLLSL | ETDKCTEYPN | EVISFSSVNE | IDIRSCPLTP |
100:
NEMHGGTIIW | YKNDSKTPIS | ADKDSRIHQQ | NEHLWFVPAK | MEDSGYYYCI |
150:
MRNSTYCLKT | KITMSVLEND | PGLCYNTQAS | FIQRLHVAGD | GSLVCPYLDF |
200:
FKDENNELPK | VQWYKNCKPL | PLDDGNFFGF | KNKLMVMNVA | EEHRGNYTCR |
250:
TSYTYQGKQY | PVTRVITFIT | IDDSKRDRPV | IMSPRNETME | ADPGSTIQLI |
300:
CNVTGQFTDL | VYWKWNGSEI | EWDDPILAED | YQFLEHPSAK | RKYTLITTLN |
350:
VSEVKSQFYR | YPFICFVKNT | HILETAHVRL | VYPVPDFKNY | LIGGFAIFTA |
400:
TAVFCACIYK | VFKVDIVLWY | RDSCSDFLPR | KASDGRTYDA | YVLYPKTYGE |
450:
GSFAYLDTFV | FKLLPEVLEG | QFGYKLFICG | RDDYVGEDTI | EVTNENVKRS |
500:
RRLIIILVRD | MGSFSCLGQS | SEEQIAIYDA | LIREGIKIIL | LELEKIQDYE |
550:
KMPESIQFIK | QKHGAICWSG | DFKERPQSAK | TRFWKNLRYQ | MPAQRRSPLS |
576:
KHHLLTLDPV | LDTKEKLQAE | THLPLG
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
ELISA Kit for Rat IL-1R-1
ELISA Kit for Rat IL-1R-1
ELISA Kit for Rat IL-1R-1
Polyclonal Antibody for Rat IL-1R-1
Polyclonal Antibody for Rat IL-1R-1
Polyclonal Antibody for Rat IL-1R-1
Monoclonal Antibody for Rat IL-1R-1
Monoclonal Antibody for Rat IL-1R-1
Monoclonal Antibody for Rat IL-1R-1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
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Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Ganglion .