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Index > Protein center > Ilf3(Gene name) > Mouse
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  • Ilf3 (Gene name),
  • Interleukin enhancer-binding factor 3 (Protein name ),  ILF3_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Ilf3;
    Protein name:
    Interleukin enhancer-binding factor 3;
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Identified in a mRNP complex, at least composed of DHX9, DDX3X, ELAVL1, HNRNPU, IGF2BP1, ILF3, PABPC1, PCBP2, PTBP2, STAU1, STAU2, SYNCRIP and YBX1. Identified in a mRNP granule complex, at least composed of ACTB, ACTN4, DHX9, ERG, HNRNPA1, HNRNPA2B1, HNRNPAB, HNRNPD, HNRNPL, HNRNPR, HNRNPU, HSPA1, HSPA8, IGF2BP1, ILF2, ILF3, NCBP1, NCL, PABPC1, PABPC4, PABPN1, RPLP0, RPS3, RPS3A, RPS4X, RPS8, RPS9, SYNCRIP, TROVE2, YBX1 and untranslated mRNAs. Interacts with FUS and SMN proteins and with PRMT1. Forms a complex with ILF2. Can also bind to PRKDC/XRCC7: this may stabilize the interaction of PRKDC/XRCC7 and the heterodimeric complex of XRCC6/KU70 and XRCC5/KU80. Forms a heteromeric complex with ZNF346 and ILF3. Found in a nuclear export complex with XPO5, ILF3, Ran and double-stranded RNA or double-stranded minihelix VA1 RNA. Found in a nuclear export complex with XPO5, RAN, ILF3, ZNF346 and double-stranded RNA. Interacts with XPO5 and ZNF346. Forms a complex with ILF2, YLPM1, KHDRBS1, RBMX, NCOA5 and PPP1CA Interacts with EIF2C1 and EIF2C2.
    Function:
    May facilitate double-stranded RNA-regulated gene expression at the level of post-transcription. Can act as a translation inhibitory protein which binds to coding sequences of acid beta-glucosidase (GCase) and other mRNAs and functions at the initiation phase of GCase mRNA translation, probably by inhibiting its binding to polysomes. Can regulate protein arginine N-methyltransferase 1 activity. Can promote the formation of stable DNA-dependent protein kinase holoenzyme complexes on DNA.
    Subcellular Location:
    Nucleus nucleolus Cytoplasm Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
    Protein Attributes:
    Sequence length:
    898
    Sequence:
    50:
    MRPMRIFVND | DRHVMAKHSS | VYPTQEELEA | VQNMVSHTER | ALKAVSDWID | 
    100:
    EQEKGNSELS | EAENMDTPPD | DESKEGAGEQ | KAEHMTRTLR | GVMRVGLVAK | 
    150:
    GLLLKGDLDL | ELVLLCKEKP | TTALLDKVAD | NLAIQLTTVT | EDKYEILQSV | 
    200:
    DDAAIVIKNT | KEPPLSLTIH | LTSPVVREEM | EKVLAGETLS | VNDPPDVLDR | 
    250:
    QKCLAALASL | RHAKWFQARA | NGLKSCVIVI | RVLRDLCTRV | PTWGPLRGWP | 
    300:
    LELLCEKSIG | TANRPMGAGE | ALRRVLECLA | SGIVMPDGSG | IYDPCEKEAT | 
    350:
    DAIGHLDRQQ | REDITQSAQH | ALRLAAFGQL | HKVLGMDPLP | SKMPKKPKNE | 
    400:
    NPVDYTVQIP | PSTTYAITPM | KRPMEEDGEE | KSPSKKKKKI | QKKEEKADPP | 
    450:
    QAMNALMRLN | QLKPGLQYKL | ISQTGPVHAP | IFTMSVEVDG | SNFEASGPSK | 
    500:
    KTAKLHVAVK | VLQDMGLPTG | AEGRDSSKGE | DSAEESDGKP | AIVAPPPVVE | 
    550:
    AVSNPSSVFP | SDATTEQGPI | LTKHGKNPVM | ELNEKRRGLK | YELISETGGS | 
    600:
    HDKRFVMEVE | VDGQKFQGAG | SNKKVAKAYA | ALAALEKLFP | DTPLALEANK | 
    650:
    KKRTPVPVRG | GPKFAAKPHN | PGFGMGGPMH | NEVPPPPNIR | GRGRGGNIRG | 
    700:
    RGRGRGFGGA | NHGGGYMNAG | AGYGSYGYSS | NSATAGYSQF | YSNGGHSGNA | 
    750:
    GGGGSGGGGG | SSSYSSYYQG | DSYNSPVPPK | HAGKKPLHGG | QQKASYSSGY | 
    800:
    QSHQGQQQPY | NQSQYSSYGT | PQGKQKGYGH | GQGSYSSYSN | SYNSPGGGGG | 
    850:
    SDYSYDSKFN | YSGSGGRSGG | NSYGSSGSSS | YNTGSHGGYG | TGSGGSSSYQ | 
    898:
    GKQGGYSSQS | NYSSPGSSQS | YSGPASSYQS | SQGGYSRNTE | HSMNYQYR
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    KEGG:
    SMR:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Interleukin enhancer-binding factor 3
    Cat.:
    E2285h
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    Packing:
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    ELISA Kit for Mouse Interleukin enhancer-binding factor 3
    Cat.:
    E2285m
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    Packing:
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    ELISA Kit for Mouse Interleukin enhancer-binding factor 3
    Cat.:
    E2285r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Interleukin enhancer-binding factor 3
    Cat.:
    U2285r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Interleukin enhancer-binding factor 3
    Cat.:
    U2285h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Interleukin enhancer-binding factor 3
    Cat.:
    U2285m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Interleukin enhancer-binding factor 3
    Cat.:
    P2285Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Interleukin enhancer-binding factor 3
    Cat.:
    P2285Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Interleukin enhancer-binding factor 3
    Cat.:
    P2285Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Interleukin enhancer-binding factor 3
    Monoclonal Antibody for Mouse Interleukin enhancer-binding factor 3
    Monoclonal Antibody for Mouse Interleukin enhancer-binding factor 3
    Protein for Mouse Interleukin enhancer-binding factor 3
    Protein for Mouse Interleukin enhancer-binding factor 3
    Protein for Mouse Interleukin enhancer-binding factor 3

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Cloning and expression of cyclosporin A- and FK506-sensitive nuclear factor of activated T-cells: NF45 and NF90."
      Kao P.N. , Chen L. , Brock G. , Ng J. , Kenny J. , Smith A.J. , Corthesy B.
      J. Biol. Chem.269:20691-20699(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 1)
    2. 2.
      "Cloning and characterization of the mouse interleukin enhancer binding factor 3 (Ilf3) homolog in a screen for RNA binding proteins."
      Buaas F.W. , Lee K. , Edelhoff S. , Disteche C. , Braun R.E.
      Mamm. Genome10:451-456(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3);CHARACTERIZATION
      tissue: Testis.
    3. 3.
      "Alternative splicing generates two mRNA transcripts of mouse interleukin enhancer binding factor 3 (Ilf3)."
      Gasmi L. , Viranaicken W. , Denoulet P. , Larcher J.-C.
      Submitted (2002-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 3)
    4. 4.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-516 (ISOFORM 2);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 549-898
      strain: C57BL/6J.
      tissue: Embryo.
      tissue: Head.
      tissue: Thymus.
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      strain: FVB/N-3.
      tissue: Mammary tumor.
    6. 6.
      "Ilf3 and NF90 associate with the axonal targeting element of Tau mRNA."
      Larcher J.-C. , Gasmi L. , Viranaicken W. , Edde B. , Bernard R. , Ginzburg I. , Denoulet P.
      FASEB J.18:1761-1763(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 163-176; 421-434; 614-628 AND 853-867
    7. 7.
      "Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry."
      Sweet S.M. , Bailey C.M. , Cunningham D.L. , Heath J.K. , Cooper H.J.
      Mol. Cell. Proteomics8:904-912(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Embryonic fibroblast.
    8. 8.
      "Phosphorylation of the NFAR proteins by the dsRNA-dependent protein kinase PKR constitutes a novel mechanism of translational regulation and cellular defense."
      Harashima A. , Guettouche T. , Barber G.N.
      Genes Dev.24:2640-2653(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;PHOSPHORYLATION AT THR-188 AND THR-315
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