Inhibin beta B chain (Protein name
), INHBB_PIG from NCBI database.
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General Annotation
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Antigen Annotation
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3D
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Predicted Eptitope
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Vaild Sequence
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Gene name:
INHBB;
Protein name:
Inhibin beta B chain;
Alternative:
Activin beta-B chain;
Organism:
Pig (Sus scrofa).
General Annotation
Sub Unit:
Dimeric, linked by one or more disulfide bonds. Inhibin A is a dimer of alpha and beta-A. Inhibin B is a dimer of alpha and beta-B. Activin A is a homodimer of beta-A. Activin B is a homodimer of beta-B. Activin AB is a dimer of beta-A and beta-B. Interacts with FST and FSTL3.
Function:
Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
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Precision
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Recovery
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Linearity
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References
1.
"Molecular cloning of the porcine inhibin-beta B precursor subunit gene and reassignment to chromosome 15." Nonneman D.J.
,
Rohrer G.A.
Submitted (2002-05) to the EMBL/GenBank/DDBJ databases
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Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]