Ireb2 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comIreb2 ELISA Kit for Rat(Rattus norvegicus)

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Ireb2 (Gene name),

Iron-responsive element-binding protein 2 (Protein name ), IREB2_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Ireb2(Irp2);

Protein name:

Iron-responsive element-binding protein 2(IRE-BP 2);

Alternative:

Iron regulatory protein 2(IRP2);

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Interacts with RBCK1 only in iron-rich conditions. Interacts (when associated with the 4Fe-4S) with FBXL5.

Function:

RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.

Subcellular Location:

Cytoplasm

Protein Attributes:

Sequence length:

963

Sequence:

50:

100:

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950:

963:

HGGLLNFVAR | KFL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Rn.10132

SMR:

Q62751

STRING:

10116.ENSRNOP00000017900

KEGG:

rno:64831

Pfam:

PF00330

String:

Q62751

Uniprot:

Q62751

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ELISA Kit for Rat IRE-BP 2

Cat.:

E13568h

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96T

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ELISA Kit for Rat IRE-BP 2

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ELISA Kit for Rat IRE-BP 2

Cat.:

E13568r

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ELISA Kit for Rat IRE-BP 2

Cat.:

E13568m

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Packing:

96T

ELISA Kit for Rat IRE-BP 2

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CLIA Kit for Rat IRE-BP 2

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CLIA Kit for Rat IRE-BP 2

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CLIA Kit for Rat IRE-BP 2

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CLIA Kit for Rat IRE-BP 2

Cat.:

U13568h

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96T

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CLIA Kit for Rat IRE-BP 2

Cat.:

U13568m

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MSDS:

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Packing:

96T

Polyclonal Antibody for Rat IRE-BP 2

Monoclonal Antibody for Rat IRE-BP 2

Protein for Rat IRE-BP 2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Characterization and expression of iron regulatory protein 2 (IRP2). Presence of multiple IRP2 transcripts regulated by intracellular iron levels."
Guo B. , Brown F.M. , Phillips J.D. , Yu Y. , Leibold E.A.
J. Biol. Chem.270:16529-16535(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: Sprague-Dawley.
tissue: Liver.
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Testis.
3.

"Iron regulates the intracellular degradation of iron regulatory protein 2 by the proteasome."
Guo B. , Phillips J.D. , Yu Y. , Leibold E.A.
J. Biol. Chem.270:21645-21651(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: COFACTOR;RNA-BINDING;UBIQUITINATION

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