"Virus-specific activation of a novel interferon regulatory factor, IRF-5, results in the induction of distinct interferon alpha genes."
Barnes B.J. , Moore P.A. , Pitha P.M.
J. Biol. Chem.276:23382-23390(2001) [PubMed] [Europe PMC] [Abstract]

"The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling."
Schoenemeyer A. , Barnes B.J. , Mancl M.E. , Latz E. , Goutagny N. , Pitha P.M. , Fitzgerald K.A. , Golenbock D.T.
J. Biol. Chem.280:17005-17012(2005) [PubMed] [Europe PMC] [Abstract]

"Two discrete promoters regulate the alternatively spliced human interferon regulatory factor-5 isoforms. Multiple isoforms with distinct cell type-specific expression, localization, regulation, and function."
Mancl M.E. , Hu G. , Sangster-Guity N. , Olshalsky S.L. , Hoops K. , Fitzgerald-Bocarsly P. , Pitha P.M. , Pinder K. , Barnes B.J.
J. Biol. Chem.280:21078-21090(2005) [PubMed] [Europe PMC] [Abstract]

"A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus."
Graham R.R. , Kozyrev S.V. , Baechler E.C. , Reddy M.V. , Plenge R.M. , Bauer J.W. , Ortmann W.A. , Koeuth T. , Escribano M.F. , Collaborative Groups T.A. , Pons-Estel B. , Petri M. , Daly M. , Gregersen P.K. , Martin J. , Altshuler D. , Behrens T.W. , Alarcon-Riquelme M.E.
Nat. Genet.38:550-555(2006) [PubMed] [Europe PMC] [Abstract]

Grossman A. , Mittrucker H.W. , Lantonio L. , Mak T.W.
Submitted (1996-04) to the EMBL/GenBank/DDBJ databases

Livingston R.J. , Shaffer T. , McFarland I. , Nguyen C.P. , Stanaway I.B. , Rajkumar N. , Johnson E.J. , da Ponte S.H. , Willa H. , Ahearn M.O. , Bertucci C. , Acklestad J. , Carroll A. , Swanson J. , Gildersleeve H.I. , Nickerson D.A.
Submitted (2006-10) to the EMBL/GenBank/DDBJ databases

"The DNA sequence of human chromosome 7."
Hillier L.W. , Fulton R.S. , Fulton L.A. , Graves T.A. , Pepin K.H. , Wagner-McPherson C. , Layman D. , Maas J. , Jaeger S. , Walker R. , Wylie K. , Sekhon M. , Becker M.C. , O'Laughlin M.D. , Schaller M.E. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Cordes M. , Du H. , Sun H. , Edwards J. , Bradshaw-Cordum H. , Ali J. , Andrews S. , Isak A. , Vanbrunt A. , Nguyen C. , Du F. , Lamar B. , Courtney L. , Kalicki J. , Ozersky P. , Bielicki L. , Scott K. , Holmes A. , Harkins R. , Harris A. , Strong C.M. , Hou S. , Tomlinson C. , Dauphin-Kohlberg S. , Kozlowicz-Reilly A. , Leonard S. , Rohlfing T. , Rock S.M. , Tin-Wollam A.-M. , Abbott A. , Minx P. , Maupin R. , Strowmatt C. , Latreille P. , Miller N. , Johnson D. , Murray J. , Woessner J.P. , Wendl M.C. , Yang S.-P. , Schultz B.R. , Wallis J.W. , Spieth J. , Bieri T.A. , Nelson J.O. , Berkowicz N. , Wohldmann P.E. , Cook L.L. , Hickenbotham M.T. , Eldred J. , Williams D. , Bedell J.A. , Mardis E.R. , Clifton S.W. , Chissoe S.L. , Marra M.A. , Raymond C. , Haugen E. , Gillett W. , Zhou Y. , James R. , Phelps K. , Iadanoto S. , Bubb K. , Simms E. , Levy R. , Clendenning J. , Kaul R. , Kent W.J. , Furey T.S. , Baertsch R.A. , Brent M.R. , Keibler E. , Flicek P. , Bork P. , Suyama M. , Bailey J.A. , Portnoy M.E. , Torrents D. , Chinwalla A.T. , Gish W.R. , Eddy S.R. , McPherson J.D. , Olson M.V. , Eichler E.E. , Green E.D. , Waterston R.H. , Wilson R.K. more...
Nature424:157-164(2003) [PubMed] [Europe PMC] [Abstract]

"Human chromosome 7: DNA sequence and biology."
Scherer S.W. , Cheung J. , MacDonald J.R. , Osborne L.R. , Nakabayashi K. , Herbrick J.-A. , Carson A.R. , Parker-Katiraee L. , Skaug J. , Khaja R. , Zhang J. , Hudek A.K. , Li M. , Haddad M. , Duggan G.E. , Fernandez B.A. , Kanematsu E. , Gentles S. , Christopoulos C.C. , Choufani S. , Kwasnicka D. , Zheng X.H. , Lai Z. , Nusskern D.R. , Zhang Q. , Gu Z. , Lu F. , Zeesman S. , Nowaczyk M.J. , Teshima I. , Chitayat D. , Shuman C. , Weksberg R. , Zackai E.H. , Grebe T.A. , Cox S.R. , Kirkpatrick S.J. , Rahman N. , Friedman J.M. , Heng H.H.Q. , Pelicci P.G. , Lo-Coco F. , Belloni E. , Shaffer L.G. , Pober B. , Morton C.C. , Gusella J.F. , Bruns G.A.P. , Korf B.R. , Quade B.J. , Ligon A.H. , Ferguson H. , Higgins A.W. , Leach N.T. , Herrick S.R. , Lemyre E. , Farra C.G. , Kim H.-G. , Summers A.M. , Gripp K.W. , Roberts W. , Szatmari P. , Winsor E.J.T. , Grzeschik K.-H. , Teebi A. , Minassian B.A. , Kere J. , Armengol L. , Pujana M.A. , Estivill X. , Wilson M.D. , Koop B.F. , Tosi S. , Moore G.E. , Boright A.P. , Zlotorynski E. , Kerem B. , Kroisel P.M. , Petek E. , Oscier D.G. , Mould S.J. , Doehner H. , Doehner K. , Rommens J.M. , Vincent J.B. , Venter J.C. , Li P.W. , Mural R.J. , Adams M.D. , Tsui L.-C. more...
Science300:767-772(2003) [PubMed] [Europe PMC] [Abstract]

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , Yooseph S. , Lu F. , Nusskern D.R. , Shue B.C. , Zheng X.H. , Zhong F. , Delcher A.L. , Huson D.H. , Kravitz S.A. , Mouchard L. , Reinert K. , Remington K.A. , Clark A.G. , Waterman M.S. , Eichler E.E. , Adams M.D. , Hunkapiller M.W. , Myers E.W. , Venter J.C. more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Structural indel variation in IRF5 is associated with a risk haplotype and defines the precise IRF5 isoforms expressed in SLE."
Kozyrev S.V. , Lewen S. , Linga-Reddy P.M.V. , Alarcon-Riquelme M.E.
Submitted (2006-09) to the EMBL/GenBank/DDBJ databases

"Multiple regulatory domains of IRF-5 control activation, cellular localization, and induction of chemokines that mediate recruitment of T lymphocytes."
Barnes B.J. , Kellum M.J. , Field A.E. , Pitha P.M.
Mol. Cell. Biol.22:5721-5740(2002) [PubMed] [Europe PMC] [Abstract]

"Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus."
Sigurdsson S. , Nordmark G. , Goering H.H.H. , Lindroos K. , Wiman A.-C. , Sturfelt G. , Joensen A. , Rantapaeae-Dahlqvist S. , Moeller B. , Kere J. , Koskenmies S. , Widen E. , Eloranta M.-L. , Julkunen H. , Kristjansdottir H. , Steinsson K. , Alm G. , Roennblom L. , Syvaenen A.-C. more...
Am. J. Hum. Genet.76:528-537(2005) [PubMed] [Europe PMC] [Abstract]

"A CRM1-dependent nuclear export pathway is involved in the regulation of IRF-5 subcellular localization."
Lin R. , Yang L. , Arguello M. , Penafuerte C. , Hiscott J.
J. Biol. Chem.280:3088-3095(2005) [PubMed] [Europe PMC] [Abstract]

"Association of a haplotype in the promoter region of the interferon regulatory factor 5 gene with rheumatoid arthritis."
Sigurdsson S. , Padyukov L. , Kurreeman F.A. , Liljedahl U. , Wiman A.C. , Alfredsson L. , Toes R. , Ronnelid J. , Klareskog L. , Huizinga T.W. , Alm G. , Syvanen A.C. , Ronnblom L.
Arthritis Rheum.56:2202-2210(2007) [PubMed] [Europe PMC] [Abstract]

"An insertion-deletion polymorphism in the interferon regulatory Factor 5 (IRF5) gene confers risk of inflammatory bowel diseases."
Dideberg V. , Kristjansdottir G. , Milani L. , Libioulle C. , Sigurdsson S. , Louis E. , Wiman A.-C. , Vermeire S. , Rutgeerts P. , Belaiche J. , Franchimont D. , Van Gossum A. , Bours V. , Syvaenen A.-C.
Hum. Mol. Genet.16:3008-3016(2007) [PubMed] [Europe PMC] [Abstract]

"Functional regulation of MyD88-activated interferon regulatory factor 5 by K63-linked polyubiquitination."
Balkhi M.Y. , Fitzgerald K.A. , Pitha P.M.
Mol. Cell. Biol.28:7296-7308(2008) [PubMed] [Europe PMC] [Abstract]

"Activation of interferon regulatory factor 5 by site specific phosphorylation."
Chang Foreman H.C. , Van Scoy S. , Cheng T.F. , Reich N.C.
PLoS ONE7:E33098-E33098(2012) [PubMed] [Europe PMC] [Abstract]

"Insights into interferon regulatory factor activation from the crystal structure of dimeric IRF5."
Chen W. , Lam S.S. , Srinath H. , Jiang Z. , Correia J.J. , Schiffer C.A. , Fitzgerald K.A. , Lin K. , Royer W.E. Jr.
Nat. Struct. Mol. Biol.15:1213-1220(2008) [PubMed] [Europe PMC] [Abstract]