Protein name:
ATP-sensitive inward rectifier potassium channel 14 ;
Alternative:
Potassium channel, inwardly rectifying subfamily J member 14 ;Inward rectifier K(+) channel Kir2.4 (IRK-4) ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Function:
Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ14 gives rise to low-conductance channels with a low affinity to the channel blockers Barium and Cesium.
Subcellular Location:
Membrane
Multi-pass membrane protein
Protein Attributes:
50:
MGLARALRRL | SGALEPGNSR | AGDEEEAGAG | LCRNGWAPGP | VAGNRRRGRF |
100:
VKKDGHCNVR | FVNLGGQGAR | YLSDLFTTCV | DVRWRWMCLL | FSCSFLASWL |
150:
LFGLTFWLIA | SLHGDLAAPP | PPAPCFSQVA | SFLAAFLFAL | ETQTSIGYGV |
200:
RSVTEECPAA | VAAVVLQCIA | GCVLDAFVVG | AVMAKMAKPK | KRNETLVFSE |
250:
NAVVALRDRR | LCLMWRVGNL | RRSHLVEAHV | RAQLLQPRVT | PEGEYIPLDH |
300:
QDVDVGFDGG | TDRIFLVSPI | TIVHEIDSAS | PLYELGRAEL | ARADFELVVI |
350:
LEGMVEATAM | TTQCRSSYLP | GELLWGHRFE | PVLFQRGSQY | EVDYRHFHRT |
400:
YEVPGTPVCS | AKELDERAEQ | ASHSPKSSFP | GSLAAFCYEN | ELALSCCQEE |
434:
DEEEDTKEGT | SAETPDRAAS | PQALTPTLAL | TLPP
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
ELISA Kit for Rat ATP-sensitive inward rectifier potassium channel 14
ELISA Kit for Rat ATP-sensitive inward rectifier potassium channel 14
ELISA Kit for Rat ATP-sensitive inward rectifier potassium channel 14
CLIA Kit for Rat ATP-sensitive inward rectifier potassium channel 14
CLIA Kit for Rat ATP-sensitive inward rectifier potassium channel 14
CLIA Kit for Rat ATP-sensitive inward rectifier potassium channel 14
Polyclonal Antibody for Rat ATP-sensitive inward rectifier potassium channel 14
Polyclonal Antibody for Rat ATP-sensitive inward rectifier potassium channel 14
Polyclonal Antibody for Rat ATP-sensitive inward rectifier potassium channel 14
Monoclonal Antibody for Rat ATP-sensitive inward rectifier potassium channel 14
Monoclonal Antibody for Rat ATP-sensitive inward rectifier potassium channel 14
Monoclonal Antibody for Rat ATP-sensitive inward rectifier potassium channel 14
Protein for Rat ATP-sensitive inward rectifier potassium channel 14
Protein for Rat ATP-sensitive inward rectifier potassium channel 14
Protein for Rat ATP-sensitive inward rectifier potassium channel 14
R&D Technical Data
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Precision
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Recovery
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Linearity
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