Protein name:
Integrin alpha-V ;
Alternative:
Vitronectin receptor subunit alpha ;
CD:
CD51 ;
Organism:
Bovine (Bos taurus).
General Annotation
Sub Unit:
Interacts with RAB25 (By similarity). Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of an heavy and a light chain linked by a disulfide bond. Alpha-V associates with either beta-1, beta-3, beta-5, beta-6 or beta-8. Alpha-V/beta-6 and alpha-V/beta-3 bind to foot-and-mouth disease virus (FMDV) VP1 protein and acts as a receptor for this virus.
Function:
The alpha-V integrins are receptors for vitronectin, MFGE8, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands.
Subcellular Location:
Membrane
Single-pass type I membrane protein
Protein Attributes:
50:
MAFPPRRRLR | LGPRGLPLLL | SGLLLPLCRA | FNLDVESPAE | YSGPEGSYFG |
100:
FAVDFFVPSA | SSRMFLLVGA | PKANTTQPGI | VEGGQVLKCD | WSSHRRCQPI |
150:
EFDATGNRDY | AKDDPLEFKS | HQWFGASVRS | KQDKILACAP | LYHWRTEMKQ |
200:
EREPVGTCFL | QDGTKTVEYA | PCRSKNIDAD | GQGFCQGGFS | IDFTKADRVL |
250:
LGGPGSFYWQ | GQLISDQVAE | IVSKYDPKVY | SIKYNNQLAT | RTAQAIFDDS |
300:
YLGYSVAVGD | FNGDGIDDFV | SGVPRAARTL | GMVYIYDGKN | MSSLHNFTGE |
350:
QMAAYFGFSV | AATDINGDDY | ADVFIGAPLF | MDRGSDGKLQ | EVGQVSVSLQ |
400:
KASGDFQTIK | LNGFEVFARF | GSAIAPLGDL | DQDGFNDIAI | AAPYGGEDKK |
450:
GIVYIFNGRP | TGLNAVPSQI | LEGKWAARSM | PPSFGYSMKG | ATDIDKNGYP |
500:
DLIVGAFGVD | RAVLYRARPV | ITVNAGLEVY | PSILNQENKT | CPLPGTDLKV |
550:
SCFNVRFCLK | ADGKGALPTK | LDFQVELLLD | KLKQKGAIRR | ALFLHNRSPG |
600:
HSKNMTISRG | GQMQCEELIA | YLRDESEFRD | KLTPITIFME | YWLDYRTAAD |
650:
ATGLQPILNQ | FTPANVSRQA | HILLDCGEDN | VCKPKLEVSV | DSDQKKIYIG |
700:
DDNPLTLIVK | AQNQGEGAYE | AELIVSIPLQ | ADFIGVVRNS | EALARLSCAF |
750:
KTENQTRQVV | CDLGNPMKAG | TQLLAGLRFS | VHQQSEMDTS | VKFDLQIQSS |
800:
NLFDKVSPVV | SYKVDLAVLA | AVEIRGVSSP | DHIFLPIPNW | KYKENPETEE |
850:
DVGPVVQHIY | ELRNNGPSSF | SKAMLHLQWP | YKYNNNTLLY | ILQYDIDGPM |
900:
NCTSDMEINP | LRIKISNSQT | SEKNDTVGGQ | GDRNHLITKR | DLTLNEGDVH |
950:
TLGCGIAECL | KIVCQVGRLD | RGKSAILYVR | SLLWTETFMN | KENQNHSYSL |
1000:
KSSASFNVIE | FPYKNLPIED | IFNSTLVTTN | VTWGIQPAPM | PVPVWVIILA |
1048:
VLAGLLLLAV | LVFVMYRMGF | FKRVRPPQEE | QEREQLQPHE | NGEGNSET
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Bovine
Mouse
Chicken
ELISA Kit for Bovine Integrin alpha-V
ELISA Kit for Bovine Integrin alpha-V
ELISA Kit for Bovine Integrin alpha-V
ELISA Kit for Bovine Integrin alpha-V
CLIA Kit for Bovine Integrin alpha-V
CLIA Kit for Bovine Integrin alpha-V
CLIA Kit for Bovine Integrin alpha-V
CLIA Kit for Bovine Integrin alpha-V
Polyclonal Antibody for Bovine Integrin alpha-V
Polyclonal Antibody for Bovine Integrin alpha-V
Polyclonal Antibody for Bovine Integrin alpha-V
Polyclonal Antibody for Bovine Integrin alpha-V
Monoclonal Antibody for Bovine Integrin alpha-V
Monoclonal Antibody for Bovine Integrin alpha-V
Monoclonal Antibody for Bovine Integrin alpha-V
Monoclonal Antibody for Bovine Integrin alpha-V
Protein for Bovine Integrin alpha-V
Protein for Bovine Integrin alpha-V
Protein for Bovine Integrin alpha-V
Protein for Bovine Integrin alpha-V
R&D Technical Data
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Precision
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Recovery
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];INTERACTION WITH FMDV CAPSID PROTEINS
tissue :
Lung .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Lung .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 42-1048
tissue :
Mammary gland .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 31-50 AND 891-910
tissue :
Mammary gland .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH HOST FMDV VP1