Gene name:
PHF17 (JADE1;KIAA1807) ;
Protein name:
Protein Jade-1 ;
Alternative:
PHD finger protein 17 ;PHD finger protein 17 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Component of the HBO1 complex composed at least of ING4 or ING5, KAT7/HBO1, MEAF6, and one of PHF15, PHF16 and PHF17. Isoform 3 interacts with VHL and KAT5.
Function:
Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Transcriptional coactivator it may also promote acetylation of nucleosomal histone H4 by KAT5. Promotes apoptosis. May act as a renal tumor suppressor.
Subcellular Location:
Cytoplasm
Nucleus
Protein Attributes:
50:
MKRGRLPSSS | EDSDDNGSLS | TTWSQNSRSQ | HRRSSCSRHE | DRKPSEVFRT |
100:
DLITAMKLHD | SYQLNPDEYY | VLADPWRQEW | EKGVQVPVSP | GTIPQPVARV |
150:
VSEEKSLMFI | RPKKYIVSSG | SEPPELGYVD | IRTLADSVCR | YDLNDMDAAW |
200:
LELTNEEFKE | MGMPELDEYT | MERVLEEFEQ | RCYDNMNHAI | ETEEGLGIEY |
250:
DEDVVCDVCQ | SPDGEDGNEM | VFCDKCNICV | HQACYGILKV | PEGSWLCRTC |
300:
ALGVQPKCLL | CPKKGGAMKP | TRSGTKWVHV | SCALWIPEVS | IGSPEKMEPI |
350:
TKVSHIPSSR | WALVCSLCNE | KFGASIQCSV | KNCRTAFHVT | CAFDRGLEMK |
400:
TILAENDEVK | FKSYCPKHSS | HRKPEESLGK | GAAQENGAPE | CSPRNPLEPF |
450:
ASLEQNREEA | HRVSVRKQKL | QQLEDEFYTF | VNLLDVARAL | RLPEEVVDFL |
500:
YQYWKLKRKV | NFNKPLITPK | KDEEDNLAKR | EQDVLFRRLQ | LFTHLRQDLE |
550:
RVRNLTYMVT | RREKIKRSVC | KVQEQIFNLY | TKLLEQERVS | GVPSSCSSSS |
600:
LENMLLFNSP | SVGPDAPKIE | DLKWHSAFFR | KQMGTSLVHS | LKKPHKRDPL |
650:
QNSPGSEGKT | LLKQPDLCGR | REGMVVPESF | LGLEKTFAEA | RLISAQQKNG |
700:
VVMPDHGKRR | DNRFHCDLIK | GDLKDKSFKQ | SHKPLRSTDV | SQRHLDNTRA |
750:
ATSPGVGQSA | PGTRKEIVPK | CNGSLIKVNY | NQTAVKVPTT | PASPVKNWGG |
800:
FRIPKKGERQ | QQGEAHDGAC | HQHSDYPYLG | LGRVPAKERA | KSKLKSDNEN |
842:
DGYVPDVEMS | DSESEASEKK | CIHTSSTISR | RTDIIRRSIL | AS
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Bovine
Mouse
ELISA Kit for Human Protein Jade-1
ELISA Kit for Human Protein Jade-1
ELISA Kit for Human Protein Jade-1
CLIA Kit for Human Protein Jade-1
CLIA Kit for Human Protein Jade-1
CLIA Kit for Human Protein Jade-1
Polyclonal Antibody for Human Protein Jade-1
Polyclonal Antibody for Human Protein Jade-1
Polyclonal Antibody for Human Protein Jade-1
Monoclonal Antibody for Human Protein Jade-1
Monoclonal Antibody for Human Protein Jade-1
Monoclonal Antibody for Human Protein Jade-1
Protein for Human Protein Jade-1
Protein for Human Protein Jade-1
Protein for Human Protein Jade-1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3);INTERACTION WITH VHL;TISSUE SPECIFICITY;SUBCELLULAR LOCATION
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 3)
tissue :
Hippocampus .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
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Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
tissue :
Cervix .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 141-842
tissue :
Brain .
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION (ISOFORM 1)
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH KAT5;SUBCELLULAR LOCATION;FUNCTION
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY;FUNCTION
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION IN HISTONE H4 ACETYLATION;IDENTIFICATION BY MASS SPECTROMETRY;IDENTIFICATION IN THE HBO1 COMPLEX
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-89 AND THR-92;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .
12.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
13.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-92 AND SER-603;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Leukemic T-cell .
14.
"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V.
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Vermeulen M.
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Santamaria A.
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Kumar C.
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Miller M.L.
,
Jensen L.J.
,
Gnad F.
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Cox J.
,
Jensen T.S.
,
Nigg E.A.
,
Brunak S.
,
Mann M.
Sci. Signal.3:RA3-RA3(2010)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-603;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .
15.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-603 AND SER-743;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]