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Index > Protein center > Phf17(Gene name) > Mouse
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  • Phf17 (Gene name),
  • Protein Jade-1 (Protein name ),  JADE1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Phf17(Jade1;Kiaa1807);
    Protein name:
    Protein Jade-1;
    Alternative:
    PHD finger protein 17;PHD finger protein 17;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Component of the HBO1 complex composed at least of ING4 or ING5, MYST2/HBO1, MEAF6, and one of PHF15, PHF16 and PHF17 (By similarity). Isoform 2 interacts with VHL and KAT5.
    Function:
    Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Transcriptional coactivator it may also promote acetylation of nucleosomal histone H4 by KAT5. Promotes apoptosis. May act as a renal tumor suppressor.
    Subcellular Location:
    Cytoplasm Nucleus
    Protein Attributes:
    Sequence length:
    834
    Sequence:
    50:
    MKRGRLPSSS | EDSDDNGSLS | TTWSQHSRSQ | HGRSSTCSRP | EDRKPSEVFR | 
    100:
    TDLITAMKLH | DSYQLNPDDY | YVLADPWRQE | WEKGVQVPVS | PGTIPQPVAR | 
    150:
    VVSEEKSLMF | IRPKKYIASS | GSEPPALGYV | DIRTLADSVC | RYDLNDMDAA | 
    200:
    WLEVTNEEFK | EMGMPELDEY | TMERVLEEFE | QRCYDNMNHA | IETEEGLGIE | 
    250:
    YDEDVVCDVC | QSPDGEDGNE | MVFCDKCNIC | VHQACYGILK | VPEGSWLCRT | 
    300:
    CALGVQPKCL | LCPKKGGAMK | PTRSGTKWVH | VSCALWIPEV | SIGSPEKMEP | 
    350:
    ITKVSHIPSS | RWALVCSLCN | EKFGASIQCS | VKNCRTAFHV | TCAFDRGLEM | 
    400:
    KTILAENDEV | KFKSYCPKHS | SHRKPEEGLG | EGAAQENGAP | ESSPQSPLEP | 
    450:
    YGSLEPNREE | AHRVSVRKQK | LQQLEDEFYT | FVNLLDVARA | LRLPEEVVDF | 
    500:
    LYQYWKLKRK | INFNKPLITP | KKDEEDNLAK | REQDVLFRRL | QLFTHLRQDL | 
    550:
    ERVRNLTYMV | TRREKIKRSV | CKVQEQIFTQ | YTKLLEQEKV | SGVPSSCSSA | 
    600:
    LENMLFFNSP | SVGPNAPKIE | DLKWHSAFFR | KQMGTSLVHP | LKKSHKRDAV | 
    650:
    QNSSGTEGKT | SHKQPGLCGR | REGLEVSESL | LSLEKTFAEA | RLLSSAQQKN | 
    700:
    GVVTPDHGKR | RDNRFHCDLV | KGDLKDKSFK | QSHKPLRSTD | TSQRHLDNTR | 
    750:
    AATSPGVGQS | APGTRKEIVP | KCNGSLVKVP | ITPASPVKSW | GGFRIPKKGE | 
    800:
    RQQQGEAHDG | ACHQHSDCSH | LGVSRAPAKE | RAKSRLRADS | ENDGYAPDGE | 
    834:
    MSDSESEASE | KKCIHASSTI | SRRTDIIRRS | ILAS
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    SMR:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Protein Jade-1
    ELISA Kit for Mouse Protein Jade-1
    ELISA Kit for Mouse Protein Jade-1
    CLIA Kit for Mouse Protein Jade-1
    CLIA Kit for Mouse Protein Jade-1
    CLIA Kit for Mouse Protein Jade-1
    Polyclonal Antibody for Mouse Protein Jade-1
    Polyclonal Antibody for Mouse Protein Jade-1
    Polyclonal Antibody for Mouse Protein Jade-1
    Monoclonal Antibody for Mouse Protein Jade-1
    Monoclonal Antibody for Mouse Protein Jade-1
    Monoclonal Antibody for Mouse Protein Jade-1
    Protein for Mouse Protein Jade-1
    Protein for Mouse Protein Jade-1
    Protein for Mouse Protein Jade-1

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Prediction of the coding sequences of mouse homologues of KIAA gene: III. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
      Okazaki N. , Kikuno R. , Ohara R. , Inamoto S. , Koseki H. , Hiraoka S. , Saga Y. , Nagase T. , Ohara O. , Koga H.
      DNA Res.10:167-180(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      strain: C57BL/6J.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      strain: FVB/N.
      tissue: Mammary gland.
    4. 4.
      "Identification of Jade1, a gene encoding a PHD zinc finger protein, in a gene trap mutagenesis screen for genes involved in anteroposterior axis development."
      Tzouanacou E. , Tweedie S. , Wilson V.
      Mol. Cell. Biol.23:8553-8562(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION;ALTERNATIVE SPLICING;DEVELOPMENTAL STAGE;SUBCELLULAR LOCATION;DISRUPTION PHENOTYPE
      strain: C57BL/6.
    5. 5.
      "The von Hippel-Lindau tumor suppressor stabilizes novel plant homeodomain protein Jade-1."
      Zhou M.I. , Wang H. , Ross J.J. , Kuzmin I. , Xu C. , Cohen H.T.
      J. Biol. Chem.277:39887-39898(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    6. 6.
      "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
      Park J. , Chen Y. , Tishkoff D.X. , Peng C. , Tan M. , Dai L. , Xie Z. , Zhang Y. , Zwaans B.M. , Skinner M.E. , Lombard D.B. , Zhao Y.
      Mol. Cell50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-609;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Embryonic fibroblast.
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