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Index > Protein center > PHF15(Gene name) > Human
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  • PHF15 (Gene name),
  • Protein Jade-2 (Protein name ),  JADE2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    PHF15(JADE2;KIAA0239);
    Protein name:
    Protein Jade-2;
    Alternative:
    PHD finger protein 15;PHD finger protein 15;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Component of the HBO1 complex composed at least of ING4 or ING5, MYST2/HBO1, MEAF6, and one of PHF15, PHF16 and PHF17.
    Function:
    Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    790
    Sequence:
    50:
    MEEKRRKYSI | SSDNSDTTDS | HATSTSASRC | SKLPSSTKSG | WPRQNEKKPS | 
    100:
    EVFRTDLITA | MKIPDSYQLS | PDDYYILADP | WRQEWEKGVQ | VPAGAEAIPE | 
    150:
    PVVRILPPLE | GPPAQASPSS | TMLGEGSQPD | WPGGSRYDLD | EIDAYWLELI | 
    200:
    NSELKEMERP | ELDELTLERV | LEELETLCHQ | NMARAIETQE | GLGIEYDEDV | 
    250:
    VCDVCRSPEG | EDGNEMVFCD | KCNVCVHQAC | YGILKVPTGS | WLCRTCALGV | 
    300:
    QPKCLLCPKR | GGALKPTRSG | TKWVHVSCAL | WIPEVSIGCP | EKMEPITKIS | 
    350:
    HIPASRWALS | CSLCKECTGT | CIQCSMPSCV | TAFHVTCAFD | HGLEMRTILA | 
    400:
    DNDEVKFKSF | CQEHSDGGPR | NEPTSEPTEP | SQAGEDLEKV | TLRKQRLQQL | 
    450:
    EEDFYELVEP | AEVAERLDLA | EALVDFIYQY | WKLKRKANAN | QPLLTPKTDE | 
    500:
    VDNLAQQEQD | VLYRRLKLFT | HLRQDLERVR | NLCYMVTRRE | RTKHAICKLQ | 
    550:
    EQIFHLQMKL | IEQDLCRGLS | TSFPIDGTFF | NSWLAQSVQI | TAENMAMSEW | 
    600:
    PLNNGHREDP | APGLLSEELL | QDEETLLSFM | RDPSLRPGDP | ARKARGRTRL | 
    650:
    PAKKKPPPPP | PQDGPGSRTT | PDKAPKKTWG | QDAGSGKGGQ | GPPTRKPPRR | 
    700:
    TSSHLPSSPA | AGDCPILATP | ESPPPLAPET | PDEAASVAAD | SDVQVPGPAA | 
    750:
    SPKPLGRLRP | PRESKVTRRL | PGARPDAGMG | PPSAVAERPK | VSLHFDTETD | 
    790:
    GYFSDGEMSD | SDVEAEDGGV | QRGPREAGAE | EVVRMGVLAS | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    MIM:
    UniGene:
    SMR:
    KEGG:
    String:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Protein Jade-2
    ELISA Kit for Human Protein Jade-2
    CLIA Kit for Human Protein Jade-2
    CLIA Kit for Human Protein Jade-2
    Polyclonal Antibody for Human Protein Jade-2
    Polyclonal Antibody for Human Protein Jade-2
    Monoclonal Antibody for Human Protein Jade-2
    Monoclonal Antibody for Human Protein Jade-2
    Protein for Human Protein Jade-2
    Protein for Human Protein Jade-2

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    Linearity
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    References
    1. 1.
      "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain."
      Nagase T. , Seki N. , Ishikawa K. , Ohira M. , Kawarabayasi Y. , Ohara O. , Tanaka A. , Kotani H. , Miyajima N. , Nomura N.
      DNA Res.3:321-329(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Bone marrow.
    2. 2.
      "Characterization of long cDNA clones from human adult spleen. II. The complete sequences of 81 cDNA clones."
      Jikuya H. , Takano J. , Kikuno R. , Hirosawa M. , Nagase T. , Nomura N. , Ohara O.
      DNA Res.10:49-57(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
      tissue: Spleen.
    3. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      tissue: Melanoma.
      tissue: Uterus.
    5. 6.
      "Isolation and characterisation of a 64 kDa protein associated with the lysosomal/autophagic compartment."
      Tesmann S. , Biederbick A. , Elsaesser H.P.
      Submitted (1999-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 202-790 (ISOFORM 1)
    6. 7.
      "Identification of Jade1, a gene encoding a PHD zinc finger protein, in a gene trap mutagenesis screen for genes involved in anteroposterior axis development."
      Tzouanacou E. , Tweedie S. , Wilson V.
      Mol. Cell. Biol.23:8553-8562(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION
    7. 8.
      "ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation."
      Doyon Y. , Cayrou C. , Ullah M. , Landry A.-J. , Cote V. , Selleck W. , Lane W.S. , Tan S. , Yang X.-J. , Cote J.
      Mol. Cell21:51-64(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN HISTONE H4 ACETYLATION;IDENTIFICATION BY MASS SPECTROMETRY;IDENTIFICATION IN THE HBO1 COMPLEX
    8. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    9. 10.
      "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
      Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-32; LYS-38 AND LYS-298;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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