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Index > Protein center > F11R(Gene name) > Bovine
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  • F11R (Gene name),
  • Junctional adhesion molecule A (Protein name ),  JAM1_BOVIN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    F11R(JAM1);
    Protein name:
    Junctional adhesion molecule A(JAM-A);
    Alternative:
    Junctional adhesion molecule 1(JAM-1);
    CD:
    CD321;
    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    Interacts with the ninth PDZ domain of MPDZ. Interacts with the first PDZ domain of PARD3. The association between PARD3 and PARD6B probably disrupts this interaction. Interacts with the orthoreovirus sigma-1 capsid protein.
    Function:
    Seems to plays a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus.
    Subcellular Location:
    Cell junction tight junction Cell membrane Single-pass type I membrane protein Localized at tight junctions of both epithelial and endothelial cells.
    Protein Attributes:
    Sequence length:
    298
    Sequence:
    50:
    MGTKAKVGST | ELLLFTSMIL | CSLALGRGAV | QTYEPVVRVP | ENNPAKLSCS | 
    100:
    YSGFSSPRVE | WKFTHGDIRG | LVCYNNKITA | SYENRVTFSD | TGITFHSVTR | 
    150:
    KDTGMYTCMV | SDEGGNTYGE | VTVQLIVLVP | PSKPTINVPS | SVTIGTRAVL | 
    200:
    TCSERDGSPP | SEYKWFKDGV | EMPLEPKSNR | AFSNSSYTLN | QKTGELIFDP | 
    250:
    VSASDTGDFT | CQAQNGYASP | VKSDTVHMDA | VELNVGGIVA | AVFVTLILLG | 
    298:
    ALIFGIWFAY | SRGYFDRAKK | GTSNKKVIYS | QPNARSDGEF | RQTSSFLV
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    String:
    UniGene:
    SMR:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Bovine JAM-A
    ELISA Kit for Bovine JAM-A
    ELISA Kit for Bovine JAM-A
    ELISA Kit for Bovine JAM-A
    CLIA Kit for Bovine JAM-A
    CLIA Kit for Bovine JAM-A
    CLIA Kit for Bovine JAM-A
    CLIA Kit for Bovine JAM-A
    Polyclonal Antibody for Bovine JAM-A
    Polyclonal Antibody for Bovine JAM-A
    Polyclonal Antibody for Bovine JAM-A
    Polyclonal Antibody for Bovine JAM-A
    Monoclonal Antibody for Bovine JAM-A
    Monoclonal Antibody for Bovine JAM-A
    Monoclonal Antibody for Bovine JAM-A
    Monoclonal Antibody for Bovine JAM-A
    Protein for Bovine JAM-A
    Protein for Bovine JAM-A
    Protein for Bovine JAM-A
    Protein for Bovine JAM-A

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    Precision
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    References
    1. 1.
      "Combined treatment of TNF-alpha and IFN-gamma causes redistribution of junctional adhesion molecule in human endothelial cells."
      Ozaki H. , Ishii K. , Horiuchi H. , Arai H. , Kawamoto T. , Okawa K. , Iwamatsu A. , Kita T.
      J. Immunol.163:553-557(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    3. 3.
      NIH - Mammalian Gene Collection (MGC) project
      Submitted (2005-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: Crossbred X Angus.
      tissue: Ileum.
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