Protein name:
Junctional adhesion molecule C (JAM-C) ;
Alternative:
Junctional adhesion molecule 3 (JAM-3) ;JAM-2 ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with JAM2 (By similarity). Interacts with ITGAM.
Function:
Participates in cell-cell adhesion. It is a counterreceptor for ITGAM mediating leukocyte-platelet interactions and is involved in the regulation of transepithelial migration of polymorphonuclear neutrophils (PMN) (By similarity). The soluble form is a mediator of angiogenesis.
Subcellular Location:
Cell membrane
Single-pass type I membrane protein
Cell junction
desmosome
Secreted
extracellular space
In epithelial cells, it is expressed at desmosomes but not at tight junctions. Localizes at the cell surface of endothelial cells. Treatment of endothelial cells with vascular endothelial growth factor stimulates recruitement of JAM3 to cell-cell contacts.
Protein Attributes:
50:
MALSRRLRLR | LYARLPDFFL | LLLFRGCMIE | AVNLKSSNRN | PVVHEFESVE |
100:
LSCIITDSQT | SDPRIEWKKI | QDGQTTYVYF | DNKIQGDLAG | RTDVFGKTSL |
150:
RIWNVTRSDS | AIYRCEVVAL | NDRKEVDEIT | IELIVQVKPV | TPVCRIPAAV |
200:
PVGKTATLQC | QESEGYPRPH | YSWYRNDVPL | PTDSRANPRF | QNSSFHVNSE |
250:
TGTLVFNAVH | KDDSGQYYCI | ASNDAGAARC | EGQDMEVYDL | NIAGIIGGVL |
300:
VVLIVLAVIT | MGICCAYRRG | CFISSKQDGE | SYKSPGKHDG | VNYIRTSEEG |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Mouse
ELISA Kit for Mouse JAM-C
ELISA Kit for Mouse JAM-C
ELISA Kit for Mouse JAM-C
Polyclonal Antibody for Mouse JAM-C
Polyclonal Antibody for Mouse JAM-C
Polyclonal Antibody for Mouse JAM-C
Monoclonal Antibody for Mouse JAM-C
Monoclonal Antibody for Mouse JAM-C
Monoclonal Antibody for Mouse JAM-C
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
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[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6J .
tissue :
Embryo .
tissue :
Small intestine .
tissue :
Wolffian duct .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
FVB/N .
tissue :
Kidney .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 84-91 AND 146-154;IDENTIFICATION BY MASS SPECTROMETRY
strain :
C57BL/6 .
tissue :
Brain .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;TISSUE SPECIFICITY
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-192 AND ASN-198
tissue :
Myoblast .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION IN ANGIOGENESIS