Amica1 ELISA Kit for Mouse(Mus musculus) | EIAab.comAmica1 ELISA Kit for Mouse(Mus musculus)

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Index > Protein center > Amica1(Gene name) > Mouse

Amica1 (Gene name),

Junctional adhesion molecule-like (Protein name ), JAML1_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Amica1(Gm638;Jaml);

Protein name:

Junctional adhesion molecule-like;

Alternative:

Dendritic cell-specific protein CREA7(mCrea7);

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interacts with CXADR.

Function:

May function in transmigration of leukocytes through epithelial and endothelial tissues. Expressed at the plasma membrane of polymorphonuclear leukocytes, it mediates adhesive interactions with CXADR, a protein of the junctional complex of epithelial cells. Enhances myeloid leukemia cell adhesion to endothelial cells.

Subcellular Location:

Cell junction Cell membrane Single-pass type I membrane protein Localized at the plasma membrane in areas of cell-cell contacts and at the cell surface of PMN.

Protein Attributes:

Sequence length:

379

Sequence:

50:

100:

150:

200:

250:

300:

350:

379:

SEGTYMTMNP | VWPSSPKASS | LVRSSVRSK

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF07686

UniGene:

Mm.190461

SMR:

Q80UL9

String:

Q80UL9

KEGG:

mmu:270152

Uniprot:

Q80UL9

FOR

ELISA Kit for Mouse Junctional adhesion molecule-like

CLIA Kit for Mouse Junctional adhesion molecule-like

Polyclonal Antibody for Mouse Junctional adhesion molecule-like

Monoclonal Antibody for Mouse Junctional adhesion molecule-like

Protein for Mouse Junctional adhesion molecule-like

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"mCrea7, mouse ortholog of human dendritic cell specific protein Crea7."
Ahn J.H. , Jung H.R. , Lee B.-H. , Jeon C.J. , Bae Y.-S.
Submitted (2002-03) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: BALB/c.
tissue: Thymus.
2.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: B5/EGFP.
tissue: Trophoblast.
4.

"The junctional adhesion molecule JAML is a costimulatory receptor for epithelial gammadelta T cell activation."
Witherden D.A. , Verdino P. , Rieder S.E. , Garijo O. , Mills R.E. , Teyton L. , Fischer W.H. , Wilson I.A. , Havran W.L.
Science329:1205-1210(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN GAMMA-DELTA T CELL ACTIVATION;INTERACTION WITH CXADR;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
5.

"The molecular interaction of CAR and JAML recruits the central cell signal transducer PI3K."
Verdino P. , Witherden D.A. , Havran W.L. , Wilson I.A.
Science329:1210-1214(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.19 ANGSTROMS) OF 21-280 ALONE AND IN COMPLEX WITH CXADR;DOMAIN;HOMODIMERIZATION;INTERACTION WITH PI3 KINASE;GLYCOSYLATION AT ASN-79; ASN-89 AND ASN-125;DISULFIDE BONDS;MUTAGENESIS OF ASP-59; TYR-72; PHE-75; TYR-77; ARG-122; TYR-334; TYR-355 AND 360-PRO--PRO-366

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