Gene name:
JARID2 (RCJMB04_32g20;JMJ) ;
Protein name:
Protein Jumonji ;
Alternative:
Jumonji/ARID domain-containing protein 2 ;
Organism:
Chicken (Gallus gallus).
General Annotation
Sub Unit:
Associates with the PRC2 complex.
Function:
Regulator of histone methyltransferase complexes that plays an essential role in embryonic development. Acts by modulating histone methyltransferase activity and promoting the recruitment of histone methyltransferase complexes to their target genes. Binds DNA and mediates the recruitment of the PRC2 complex to target genes in embryonic stem cells. Does not have histone demethylase activity but regulates activity of various histone methyltransferase complexes. In embryonic stem cells, it associates with the PRC2 complex and inhibits trimethylation of 'Lys-27' of histone H3 (H3K27me3) by the PRC2 complex, thereby playing a key role in differentiation of embryonic stem cells and normal development.
Subcellular Location:
Nucleus
Colocalizes with the PRC2 complex on chromatin.
Protein Attributes:
50:
MSKERPKRNI | IQKEYDDSDG | IPWSEERVVR | KVLYLSLKEF | KNAQKRQHGD |
100:
GISGSLKAVN | GLLTNGQSKG | LESEQLENEK | DDASQVSSTS | NDISSSDFEE |
150:
GPSRKRPRLQ | AQRKFAQSQP | NSPSTTPIKI | VEPLLPPPAT | QISDLSKRKP |
200:
KTEDFLTFLC | LRGSPALPSN | MVYFGSSQDD | EDEEEEEEET | EDTKTATNNA |
250:
SSSCQSTPRK | GKTHKQVPNG | QVFNGSSKSL | KEKEPAQKHK | SKEATPGKEK |
300:
NSEHKAESRK | DQAAANHHPT | TNTGSSTKGL | TANNHHTLHR | SAQDLRKQVS |
350:
KVNGITRMSS | PSANAASAKK | MRDVRPSPSK | TVKYTATVTK | GTVTYTKAKK |
400:
ELVKETKLNH | HKPSSPVNHT | ISGKLESSNA | KTRKQVLSLG | ASKSNNTAVN |
450:
GVKVNGKLNQ | KTCTKEVGRQ | LREGLRNSKR | RLEETNHIDK | IQSPTKRMKG |
500:
AVNLAEAASK | KAVVEKPLLN | GHLKKEVPEK | NLERNRPKRA | TAGKSTPGKQ |
550:
AHGKTENASC | ENRSTSQAES | LHKPQDSMGK | HEKGSSKSGW | GMLGEIPILR |
600:
PSTKEFHDPL | IYIESVRAQV | EKYGMCRVIP | PPDWRPECKL | NDEMRFVTQI |
650:
QHIHKLGRRW | GPNVQRLACI | KKHLKSQGIT | MDELPLIGGC | ELDLACFVQL |
700:
INEMGGMQQV | TDLKKWNKLA | DMLRIPKTAQ | DRLAKLQEAY | CQYLLSYDSL |
750:
SPEEHKKLEK | EVLLEKEILE | KRKGPLEGHS | ENAYKFHSLP | RFEPKNGLIN |
800:
GVVHKNGFRN | KLKEVDVPLK | TGRRRLFAQE | KETTKDDEEE | EEEGVLSDLH |
850:
KCIYKGRSVS | LTTFYRTARN | IMNMCFTKEP | TVAEVEQEYW | RLVEQKDSHV |
900:
AVHCGKVDTN | THGSGFPVGK | SEPFSRHGWN | LTVLPNNTGS | ILRHLGAVPG |
950:
VTIPWLNIGM | VFSTSCWSRD | QNHLPYIDYL | HTGADCIWYC | IPAAEENKLD |
1000:
DVVHTLLQAN | GTPGLEMLES | NVMISPEILC | KEGIRVHRTV | QQSGQFVVCF |
1050:
PGSFVSKVCC | GYSVSETVHF | ATTQWTSMGF | KTAKEMKRRR | IAKPFSMEKL |
1100:
LYQIATAEAK | KENGPTLSTI | SSLLGELRDT | ELRQRRQLYE | AGLHSSARYG |
1150:
SHDSSSTAMD | GKKKPRKWLQ | LETSERRCQI | CQHLCYLSMV | VQENENVVFC |
1200:
LECALRHVEK | QKSCRGLKMM | YRYDEEQIIS | LVNQICGKVS | GKNGSIENCI |
1233:
SKPTPKRGPR | KRATVDVPSS | RLSSSSSSKS | ASS
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Chicken
ELISA Kit for Chicken Protein Jumonji
ELISA Kit for Chicken Protein Jumonji
ELISA Kit for Chicken Protein Jumonji
CLIA Kit for Chicken Protein Jumonji
CLIA Kit for Chicken Protein Jumonji
CLIA Kit for Chicken Protein Jumonji
Polyclonal Antibody for Chicken Protein Jumonji
Polyclonal Antibody for Chicken Protein Jumonji
Polyclonal Antibody for Chicken Protein Jumonji
Monoclonal Antibody for Chicken Protein Jumonji
Monoclonal Antibody for Chicken Protein Jumonji
Monoclonal Antibody for Chicken Protein Jumonji
Protein for Chicken Protein Jumonji
Protein for Chicken Protein Jumonji
Protein for Chicken Protein Jumonji
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis."
Caldwell R.B.
,
Kierzek A.M.
,
Arakawa H.
,
Bezzubov Y.
,
Zaim J.
,
Fiedler P.
,
Kutter S.
,
Blagodatski A.
,
Kostovska D.
,
Koter M.
,
Plachy J.
,
Carninci P.
,
Hayashizaki Y.
,
Buerstedde J.-M.
Genome Biol.6:R6.1-R6.9(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
CB .
tissue :
Bursa of Fabricius .