Protein name:
Jun dimerization protein 2 ;
Alternative:
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Forms homodimer or heterodimer with JUN, JUNB, JUND, CEBPG and ATF2 thereby inhibiting transactivation by JUN, ATF2 and CEBPG (By similarity). Binds multiple DNA elements such as cAMP-response element (CRE) and TPA response element (TRE) either as homodimer or heterodimer.
Function:
Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of histones and the assembly of chromatin.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MMPGQIPDPS | VTTGSLPGLG | PLTGLPSSAL | TVEELKYADI | RNLGAMIAPL |
100:
HFLEVKLGKR | PQPVKSELDE | EEERRKRRRE | KNKVAAARCR | NKKKERTEFL |
150:
QRESERLELM | NAELKTQIEE | LKQERQQLIL | MLNRHRPTCI | VRTDSVKTPE |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Rat
Human
ELISA Kit for Human Jun dimerization protein 2
ELISA Kit for Human Jun dimerization protein 2
ELISA Kit for Human Jun dimerization protein 2
CLIA Kit for Human Jun dimerization protein 2
CLIA Kit for Human Jun dimerization protein 2
CLIA Kit for Human Jun dimerization protein 2
Polyclonal Antibody for Human Jun dimerization protein 2
Polyclonal Antibody for Human Jun dimerization protein 2
Polyclonal Antibody for Human Jun dimerization protein 2
Monoclonal Antibody for Human Jun dimerization protein 2
Monoclonal Antibody for Human Jun dimerization protein 2
Monoclonal Antibody for Human Jun dimerization protein 2
Protein for Human Jun dimerization protein 2
Protein for Human Jun dimerization protein 2
Protein for Human Jun dimerization protein 2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Jun dimerization protein 2 (JDP2), a member of the AP-1 family of transcription factor, mediates osteoclast differentiation induced by RANKL."
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];FUNCTION
2.
"The DNA sequence and analysis of human chromosome 14."
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more...
Nature421:601-607(2003)
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[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
3.
Mural R.J.
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more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Colon .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
6.
"Regulation of histone acetylation and nucleosome assembly by transcription factor JDP2."
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Nat. Struct. Mol. Biol.13:331-338(2006)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION AT THR-148 BY MAPK8;IDENTIFICATION BY MASS SPECTROMETRY
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : UBIQUITINATION;INTERACTION WITH IRF2BP1