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Index > Protein center > Jdp2(Gene name) > Rat
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  • Jdp2 (Gene name),
  • Jun dimerization protein 2 (Protein name ),  JDP2_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Jdp2(Jdp-2;Jundm2;Jundp2);
    Protein name:
    Jun dimerization protein 2;
    Alternative:

    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Forms homodimer or heterodimer with JUN, JUNB, JUND, CEBPG and ATF2 thereby inhibiting transactivation by JUN, ATF2 and CEBPG. Binds multiple DNA elements such as cAMP-response element (CRE) and TPA response element (TRE) either as homodimer or heterodimer.
    Function:
    Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses associated with AP-1, such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of histones and the assembly of chromatin.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    163
    Sequence:
    50:
    MMPGQIPDPS | VTAGSLPGLG | PLTGLPSSAL | TTEELKYADI | RNIGAMIAPL | 
    100:
    HFLEVKLGKR | PQPVKSELDE | EEERRKRRRE | KNKVAAARCR | NKKKERTEFL | 
    150:
    QRESERLELM | NAELKTQIEE | LKLERQQLIL | MLNRHRPTCI | VRTDSVRTPE | 
    163:
    SEGNPLLEQL | DKK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    SMR:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Jun dimerization protein 2
    ELISA Kit for Rat Jun dimerization protein 2
    ELISA Kit for Rat Jun dimerization protein 2
    CLIA Kit for Rat Jun dimerization protein 2
    CLIA Kit for Rat Jun dimerization protein 2
    CLIA Kit for Rat Jun dimerization protein 2
    Polyclonal Antibody for Rat Jun dimerization protein 2
    Polyclonal Antibody for Rat Jun dimerization protein 2
    Polyclonal Antibody for Rat Jun dimerization protein 2
    Monoclonal Antibody for Rat Jun dimerization protein 2
    Monoclonal Antibody for Rat Jun dimerization protein 2
    Monoclonal Antibody for Rat Jun dimerization protein 2
    Protein for Rat Jun dimerization protein 2
    Protein for Rat Jun dimerization protein 2
    Protein for Rat Jun dimerization protein 2

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Isolation of an AP-1 repressor by a novel method for detecting protein-protein interactions."
      Aronheim A. , Zandi E. , Hennemann H. , Elledge S.J. , Karin M.
      Mol. Cell. Biol.17:3094-3102(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;INTERACTION WITH JUN; JUNB AND JUND;DNA-BINDING
      tissue: Pituitary.
    2. 2.
      "The ras recruitment system, a novel approach to the study of protein-protein interactions."
      Broder Y.C. , Katz S. , Aronheim A.
      Curr. Biol.8:1121-1124(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CEBPG
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