Gene name:
JKAMP (CDA06;HSPC213;HSPC327;C14orf100;JAMP) ;
Protein name:
JNK1/MAPK8-associated membrane protein (JKAMP) ;
Alternative:
Medulloblastoma antigen MU-MB-50.4 ;JNK1-associated membrane protein (JAMP) ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with RNF5 and MAPK8, but not with MAPK9. Binding to MAPK8 occurs before and after exposure to stress, such as UV irradiation. After exposure to stress, interacts with phosphorylated MAPK8. Competes with DUSP10 for MAPK8 binding. Associates with multiple components of the proteasome and with ERAD regulatory proteins including AMFR/GP78, CANX, PSMC1, PSMC2, PSMC3/TBP1, PSMC5, PSMC6, PSMD8, SEC61-ALPHA and UFD1L.
Function:
May be a regulator of the duration of MAPK8 activity in response to various stress stimuli. Facilitates degradation of misfolded endoplasmic reticulum (ER) luminal proteins through the recruitment of components of the proteasome and endoplasmic reticulum-associated degradation (ERAD) system.
Subcellular Location:
Endoplasmic reticulum membrane
Multi-pass membrane protein
Protein Attributes:
50:
MFGAAARSAD | LALLEKNLQA | AHGCLGLYCG | KTLLFKNGST | EIYGECGVCP |
100:
RGQRTNAQKY | CQPCTESPEL | YDWLYLGFMA | MLPLVLHWFF | IEWYSGKKSS |
150:
SALFQHITAL | FECSMAAIIT | LLVSDPVGVL | YIRSCRVLML | SDWYTMLYNP |
200:
SPDYVTTVHC | THEAVYPLYT | IVFIYYAFCL | VLMMLLRPLL | VKKIACGLGK |
250:
SDRFKSIYAA | LYFFPILTVL | QAVGGGLLYY | AFPYIILVLS | LVTLAVYMSA |
300:
SEIENCYDLL | VRKKRLIVLF | SHWLLHAYGI | ISISRVDKLE | QDLPLLALVP |
326:
TPALFYLFTA | KFTEPSRILS | EGANGH
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
ELISA Kit for Human JKAMP
ELISA Kit for Human JKAMP
Polyclonal Antibody for Human JKAMP
Polyclonal Antibody for Human JKAMP
Monoclonal Antibody for Human JKAMP
Monoclonal Antibody for Human JKAMP
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
tissue :
Medulloblastoma .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 3)
tissue :
Umbilical cord blood .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4)
tissue :
Fetal brain .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2; 3 AND 4)
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Embryo .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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Pheochromocytoma .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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Cervix carcinoma .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 3 AND 4)
tissue :
Bone marrow .