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Index > Protein center > JKAMP(Gene name) > Human
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  • JKAMP (Gene name),
  • JNK1/MAPK8-associated membrane protein (Protein name ),  JKAMP_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    JKAMP(CDA06;HSPC213;HSPC327;C14orf100;JAMP);
    Protein name:
    JNK1/MAPK8-associated membrane protein(JKAMP);
    Alternative:
    Medulloblastoma antigen MU-MB-50.4;JNK1-associated membrane protein(JAMP);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with RNF5 and MAPK8, but not with MAPK9. Binding to MAPK8 occurs before and after exposure to stress, such as UV irradiation. After exposure to stress, interacts with phosphorylated MAPK8. Competes with DUSP10 for MAPK8 binding. Associates with multiple components of the proteasome and with ERAD regulatory proteins including AMFR/GP78, CANX, PSMC1, PSMC2, PSMC3/TBP1, PSMC5, PSMC6, PSMD8, SEC61-ALPHA and UFD1L.
    Function:
    May be a regulator of the duration of MAPK8 activity in response to various stress stimuli. Facilitates degradation of misfolded endoplasmic reticulum (ER) luminal proteins through the recruitment of components of the proteasome and endoplasmic reticulum-associated degradation (ERAD) system.
    Subcellular Location:
    Endoplasmic reticulum membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    326
    Sequence:
    50:
    MFGAAARSAD | LALLEKNLQA | AHGCLGLYCG | KTLLFKNGST | EIYGECGVCP | 
    100:
    RGQRTNAQKY | CQPCTESPEL | YDWLYLGFMA | MLPLVLHWFF | IEWYSGKKSS | 
    150:
    SALFQHITAL | FECSMAAIIT | LLVSDPVGVL | YIRSCRVLML | SDWYTMLYNP | 
    200:
    SPDYVTTVHC | THEAVYPLYT | IVFIYYAFCL | VLMMLLRPLL | VKKIACGLGK | 
    250:
    SDRFKSIYAA | LYFFPILTVL | QAVGGGLLYY | AFPYIILVLS | LVTLAVYMSA | 
    300:
    SEIENCYDLL | VRKKRLIVLF | SHWLLHAYGI | ISISRVDKLE | QDLPLLALVP | 
    326:
    TPALFYLFTA | KFTEPSRILS | EGANGH
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    KEGG:
    String:
    MIM:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human JKAMP
    ELISA Kit for Human JKAMP
    CLIA Kit for Human JKAMP
    CLIA Kit for Human JKAMP
    Polyclonal Antibody for Human JKAMP
    Polyclonal Antibody for Human JKAMP
    Monoclonal Antibody for Human JKAMP
    Monoclonal Antibody for Human JKAMP
    Protein for Human JKAMP
    Protein for Human JKAMP

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Novel tumor antigens identified by autologous antibody screening of childhood medulloblastoma cDNA libraries."
      Behrends U. , Schneider I. , Roessler S. , Frauenknecht H. , Golbeck A. , Lechner B. , Eigenstetter G. , Zobywalski C. , Mueller-Weihrich S. , Graubner U. , Schmid I. , Sackerer D. , Spaeth M. , Goetz C. , Prantl F. , Asmuss H.-P. , Bise K. , Mautner J.
      Int. J. Cancer106:244-251(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
      tissue: Medulloblastoma.
    2. 2.
      "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells."
      Zhang Q.-H. , Ye M. , Wu X.-Y. , Ren S.-X. , Zhao M. , Zhao C.-J. , Fu G. , Shen Y. , Fan H.-Y. , Lu G. , Zhong M. , Xu X.-R. , Han Z.-G. , Zhang J.-W. , Tao J. , Huang Q.-H. , Zhou J. , Hu G.-X. , more...
      Genome Res.10:1546-1560(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 3)
      tissue: Umbilical cord blood.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4)
      tissue: Fetal brain.
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2; 3 AND 4)
      tissue: Embryo.
      tissue: Teratocarcinoma.
    5. 5.
      "A novel gene expressed in human pheochromocytoma."
      Li Y. , Huang Q. , Peng Y. , Song H. , Yu Y. , Xu S. , Ren S. , Chen Z. , Han Z.
      Submitted (1999-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
      tissue: Pheochromocytoma.
    6. 6.
      "Full-length cDNA libraries and normalization."
      Li W.B. , Gruber C. , Jessee J. , Polayes D.
      Submitted (2003-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 5)
      tissue: Cervix carcinoma.
    7. 7.
      "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
      Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
      Submitted (2004-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 3 AND 4)
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    9. 9.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 3 AND 4)
      tissue: Bone marrow.
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