Gene name:
JAKMIP1 (GABABRBP;JAMIP1;MARLIN1) ;
Protein name:
Janus kinase and microtubule-interacting protein 1 ;
Alternative:
Multiple alpha-helices and RNA-linker protein 1 (Marlin-1) ;GABA-B receptor-binding protein ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Homodimer. Forms a complex with GABBR1 and KIF5B/kinesin-1. Interacts with JAK1 and TYK2.
Function:
Associates with microtubules and may play a role in the microtubule-dependent transport of the GABA-B receptor. May play a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements.
Subcellular Location:
Cytoplasm
cytoskeleton
Membrane
Peripheral membrane protein
Colocalizes with the microtubule network. Localizes to the cell body and neurites of hippocampal neurons where it accumulates in granules. Localizes to the tail and to a lower extent to the head of sperm cells.
Protein Attributes:
50:
MSKKGRSKGE | KPEMETDAVQ | MANEELRAKL | TSIQIEFQQE | KSKVGKLRER |
100:
LQEAKLEREQ | EQRRHTAYIS | ELKAKLHEEK | TKELQALREG | LIRQHEQEAA |
150:
RTAKIKEGEL | QRLQATLNVL | RDGAADKVKT | ALLTEAREEA | RRAFDGERLR |
200:
LQQEILELKA | ARKQAEEALS | NCMQADKTKA | ADLRAAYQAH | QDEVHRIKRE |
250:
CERDIRRLMD | EIKGKDRVIL | ALEKELGVQA | GQTQKLLLQK | EALDEQLVQV |
300:
KEAERHHSSP | KRELPPGIGD | MVELMGVQDQ | HMDERDVRRF | QLKIAELNSV |
350:
IRKLEDRNTL | LADERNELLK | RSRETEVQLK | PLVEKNKRMN | KKNEDLLQSI |
400:
QRMEEKIKNL | TRENVEMKEK | LSAQASLKRH | TSLNDLSLTR | DEQEIEFLRL |
450:
QVLEQQHVID | DLSLERERLL | RSKRHRGKSL | KPPKKHVVET | FFGFDEESVD |
500:
SETLSETSYN | TDRTDRTPAT | PEEDLDDATA | REEADLRFCQ | LTREYQALQR |
550:
AYALLQEQVG | GTLDAEREAR | TREQLQADLL | RCQAKIEDLE | KLLVEKGQDS |
600:
KWVEEKQLLI | RTNQDLLEKI | YRLEMEENQL | KNEMQDAKDQ | NELLEFRVLE |
626:
LEVRDSICCK | LSNGADILFE | PKLKFM
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Mouse
Rat
Human
ELISA Kit for Human Janus kinase and microtubule-interacting protein 1
ELISA Kit for Human Janus kinase and microtubule-interacting protein 1
ELISA Kit for Human Janus kinase and microtubule-interacting protein 1
ELISA Kit for Human Janus kinase and microtubule-interacting protein 1
CLIA Kit for Human Janus kinase and microtubule-interacting protein 1
CLIA Kit for Human Janus kinase and microtubule-interacting protein 1
CLIA Kit for Human Janus kinase and microtubule-interacting protein 1
CLIA Kit for Human Janus kinase and microtubule-interacting protein 1
Polyclonal Antibody for Human Janus kinase and microtubule-interacting protein 1
Polyclonal Antibody for Human Janus kinase and microtubule-interacting protein 1
Polyclonal Antibody for Human Janus kinase and microtubule-interacting protein 1
Polyclonal Antibody for Human Janus kinase and microtubule-interacting protein 1
Monoclonal Antibody for Human Janus kinase and microtubule-interacting protein 1
Monoclonal Antibody for Human Janus kinase and microtubule-interacting protein 1
Monoclonal Antibody for Human Janus kinase and microtubule-interacting protein 1
Monoclonal Antibody for Human Janus kinase and microtubule-interacting protein 1
Protein for Human Janus kinase and microtubule-interacting protein 1
Protein for Human Janus kinase and microtubule-interacting protein 1
Protein for Human Janus kinase and microtubule-interacting protein 1
Protein for Human Janus kinase and microtubule-interacting protein 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;INTERACTION WITH GABBR1;SUBCELLULAR LOCATION
tissue :
Brain .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 2; 3; 4 AND 5);TISSUE SPECIFICITY;VARIANT ARG-251
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Brain .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 6 AND 7)
tissue :
Caudate nucleus .
tissue :
Teratocarcinoma .
tissue :
Testis .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
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Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
Brain .
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;INTERACTION WITH JAK1 AND TYK2;OLIGOMERIZATION;SUBCELLULAR LOCATION;PHOSPHORYLATION;TISSUE SPECIFICITY
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;IDENTIFICATION IN A COMPLEX WITH GABBR1 AND KIF5B
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-382 AND THR-470;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Leukemic T-cell .
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Science314:268-274(2006)
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[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANT [LARGE SCALE ANALYSIS] VAL-375