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Index > Protein center > JAKMIP1(Gene name) > Human
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  • JAKMIP1 (Gene name),
  • Janus kinase and microtubule-interacting protein 1 (Protein name ),  JKIP1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    JAKMIP1(GABABRBP;JAMIP1;MARLIN1);
    Protein name:
    Janus kinase and microtubule-interacting protein 1;
    Alternative:
    Multiple alpha-helices and RNA-linker protein 1(Marlin-1);GABA-B receptor-binding protein;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homodimer. Forms a complex with GABBR1 and KIF5B/kinesin-1. Interacts with JAK1 and TYK2.
    Function:
    Associates with microtubules and may play a role in the microtubule-dependent transport of the GABA-B receptor. May play a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements.
    Subcellular Location:
    Cytoplasm cytoskeleton Membrane Peripheral membrane protein Colocalizes with the microtubule network. Localizes to the cell body and neurites of hippocampal neurons where it accumulates in granules. Localizes to the tail and to a lower extent to the head of sperm cells.
    Protein Attributes:
    Sequence length:
    626
    Sequence:
    50:
    MSKKGRSKGE | KPEMETDAVQ | MANEELRAKL | TSIQIEFQQE | KSKVGKLRER | 
    100:
    LQEAKLEREQ | EQRRHTAYIS | ELKAKLHEEK | TKELQALREG | LIRQHEQEAA | 
    150:
    RTAKIKEGEL | QRLQATLNVL | RDGAADKVKT | ALLTEAREEA | RRAFDGERLR | 
    200:
    LQQEILELKA | ARKQAEEALS | NCMQADKTKA | ADLRAAYQAH | QDEVHRIKRE | 
    250:
    CERDIRRLMD | EIKGKDRVIL | ALEKELGVQA | GQTQKLLLQK | EALDEQLVQV | 
    300:
    KEAERHHSSP | KRELPPGIGD | MVELMGVQDQ | HMDERDVRRF | QLKIAELNSV | 
    350:
    IRKLEDRNTL | LADERNELLK | RSRETEVQLK | PLVEKNKRMN | KKNEDLLQSI | 
    400:
    QRMEEKIKNL | TRENVEMKEK | LSAQASLKRH | TSLNDLSLTR | DEQEIEFLRL | 
    450:
    QVLEQQHVID | DLSLERERLL | RSKRHRGKSL | KPPKKHVVET | FFGFDEESVD | 
    500:
    SETLSETSYN | TDRTDRTPAT | PEEDLDDATA | REEADLRFCQ | LTREYQALQR | 
    550:
    AYALLQEQVG | GTLDAEREAR | TREQLQADLL | RCQAKIEDLE | KLLVEKGQDS | 
    600:
    KWVEEKQLLI | RTNQDLLEKI | YRLEMEENQL | KNEMQDAKDQ | NELLEFRVLE | 
    626:
    LEVRDSICCK | LSNGADILFE | PKLKFM
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    MIM:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Janus kinase and microtubule-interacting protein 1
    ELISA Kit for Human Janus kinase and microtubule-interacting protein 1
    ELISA Kit for Human Janus kinase and microtubule-interacting protein 1
    ELISA Kit for Human Janus kinase and microtubule-interacting protein 1
    CLIA Kit for Human Janus kinase and microtubule-interacting protein 1
    CLIA Kit for Human Janus kinase and microtubule-interacting protein 1
    CLIA Kit for Human Janus kinase and microtubule-interacting protein 1
    CLIA Kit for Human Janus kinase and microtubule-interacting protein 1
    Polyclonal Antibody for Human Janus kinase and microtubule-interacting protein 1
    Polyclonal Antibody for Human Janus kinase and microtubule-interacting protein 1
    Polyclonal Antibody for Human Janus kinase and microtubule-interacting protein 1
    Polyclonal Antibody for Human Janus kinase and microtubule-interacting protein 1
    Monoclonal Antibody for Human Janus kinase and microtubule-interacting protein 1
    Monoclonal Antibody for Human Janus kinase and microtubule-interacting protein 1
    Monoclonal Antibody for Human Janus kinase and microtubule-interacting protein 1
    Monoclonal Antibody for Human Janus kinase and microtubule-interacting protein 1
    Protein for Human Janus kinase and microtubule-interacting protein 1
    Protein for Human Janus kinase and microtubule-interacting protein 1
    Protein for Human Janus kinase and microtubule-interacting protein 1
    Protein for Human Janus kinase and microtubule-interacting protein 1

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    Precision
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    Linearity
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    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;INTERACTION WITH GABBR1;SUBCELLULAR LOCATION
      tissue: Brain.
    2. 2.
      "Identification and expression analysis of novel Jakmip1 transcripts."
      Costa V. , Conte I. , Ziviello C. , Casamassimi A. , Alfano G. , Banfi S. , Ciccodicola A.
      Gene402:1-8(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 2; 3; 4 AND 5);TISSUE SPECIFICITY;VARIANT ARG-251
      tissue: Brain.
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 6 AND 7)
      tissue: Caudate nucleus.
      tissue: Teratocarcinoma.
      tissue: Testis.
    4. 4.
      "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
      Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Brain.
    7. 7.
      "Jamip1 (marlin-1) defines a family of proteins interacting with Janus kinases and microtubules."
      Steindler C. , Li Z. , Algarte M. , Alcover A. , Libri V. , Ragimbeau J. , Pellegrini S.
      J. Biol. Chem.279:43168-43177(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH JAK1 AND TYK2;OLIGOMERIZATION;SUBCELLULAR LOCATION;PHOSPHORYLATION;TISSUE SPECIFICITY
    8. 8.
      "Marlin-1 and conventional kinesin link GABAB receptors to the cytoskeleton and regulate receptor transport."
      Vidal R.L. , Ramirez O.A. , Sandoval L. , Koenig-Robert R. , Haertel S. , Couve A.
      Mol. Cell. Neurosci.35:501-512(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;IDENTIFICATION IN A COMPLEX WITH GABBR1 AND KIF5B
    9. 9.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-382 AND THR-470;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    10. 10.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] VAL-375
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