Jph1 ELISA Kit for Mouse(Mus musculus) | EIAab.comJph1 ELISA Kit for Mouse(Mus musculus)

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Jph1 (Gene name),

Junctophilin-1 (Protein name ), JPH1_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Jph1(Jp1);

Protein name:

Junctophilin-1(JP-1);

Alternative:

Junctophilin type 1;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

N/A

Function:

Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH1 contributes to the construction of the skeletal muscle triad by linking the t-tubule (transverse-tubule) and SR (sarcoplasmic reticulum) membranes.

Subcellular Location:

Cell membrane Peripheral membrane protein Endoplasmic reticulum membrane Single-pass type IV membrane protein Sarcoplasmic reticulum membrane Single-pass type IV membrane protein Predominantly on the plasma membrane. The transmembrane domain is anchored in endoplasmic/sarcoplasmic reticulum membrane, while the N-terminal part associates with the plasma membrane. In skeletal muscle cells, it is predominantly localized at the junction of the A and I bands.

Protein Attributes:

Sequence length:

660

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

660:

LAILFVHFLT |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

Q9ET80

UniGene:

Mm.143761

Pfam:

PF02493

KEGG:

mmu:57339

Uniprot:

Q9ET80

FOR

ELISA Kit for Mouse JP-1

CLIA Kit for Mouse JP-1

Polyclonal Antibody for Mouse JP-1

Monoclonal Antibody for Mouse JP-1

Protein for Mouse JP-1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Junctophilins: a novel family of junctional membrane complex proteins."
Takeshima H. , Komazaki S. , Nishi M. , Iino M. , Kangawa K.
Mol. Cell6:11-22(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA];TISSUE SPECIFICITY
strain: 129.
strain: C57BL/6J.
tissue: Skeletal muscle.
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Brain.
3.

"Deficiency of triad junction and contraction in mutant skeletal muscle lacking junctophilin type 1."
Ito K. , Komazaki S. , Sasamoto K. , Yoshida M. , Nishi M. , Kitamura K. , Takeshima H.
J. Cell Biol.154:1059-1067(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISRUPTION PHENOTYPE;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
4.

"Deficiency of triad formation in developing skeletal muscle cells lacking junctophilin type 1."
Komazaki S. , Ito K. , Takeshima H. , Nakamura H.
FEBS Lett.524:225-229(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISRUPTION PHENOTYPE
5.

"Abnormal junctional membrane structures in cardiac myocytes expressing ectopic junctophilin type 1."
Komazaki S. , Nishi M. , Takeshima H.
FEBS Lett.542:69-73(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;FUNCTION

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