Jph2 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comJph2 ELISA Kit for Rat(Rattus norvegicus)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > Jph2(Gene name) > Rat

Jph2 (Gene name),

Junctophilin-2 (Protein name ), JPH2_RAT from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

Jph2(Jp2);

Protein name:

Junctophilin-2(JP-2);

Alternative:

Junctophilin type 2;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

N/A

Function:

Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH2 is necessary for proper intracellular Ca(2+) signaling in cardiac myocytes via its involvement in ryanodine receptor-mediated calcium ion release. Contributes to the construction of skeletal muscle triad junctions.

Subcellular Location:

Cell membrane Peripheral membrane protein Endoplasmic reticulum membrane Single-pass type IV membrane protein Sarcoplasmic reticulum membrane Single-pass type IV membrane protein Localized predominantly on the plasma membrane. The transmembrane domain is anchored in endoplasmic/sarcoplasmic reticulum membrane, while the N-terminal part associates with the plasma membrane. In heart cells, it predominantly associates along Z lines within myocytes. In skeletal muscle, it is specifically localized at the junction of A and I bands.

Protein Attributes:

Sequence length:

692

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

692:

RKEVAQEAEA | EVEVEEVPNT | VLICMVILLN | IGLAILFVHL | LT

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

STRING:

10116.ENSRNOP00000010938

UniGene:

Rn.6206

KEGG:

rno:296345

String:

Q2PS20

Pfam:

PF02493

Uniprot:

Q2PS20

FOR

ELISA Kit for Rat JP-2

CLIA Kit for Rat JP-2

Polyclonal Antibody for Rat JP-2

Monoclonal Antibody for Rat JP-2

Protein for Rat JP-2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"The cloning of rat junctophilin-2 coding sequence."
Bai Z. , Geng X. , Bi Q. , Wang S.
Submitted (2005-11) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: Sprague-Dawley.
tissue: Heart.

Product Feedback Wall

* Email:
*Comments: