Jtb ELISA Kit for Rat(Rattus norvegicus) | EIAab.comJtb ELISA Kit for Rat(Rattus norvegicus)

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Jtb (Gene name),

Protein JTB (Protein name ), JTB_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Jtb;

Protein name:

Protein JTB;

Alternative:

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Interacts with AURKA, AURKB, BIRC5 and INCENP. May be a component of the CPC at least composed of BIRC5/survivin, CDCA8/borealin, INCENP and AURKB/Aurora-B.

Function:

Required for normal cytokinesis during mitosis. Plays a role in the regulation of cell proliferation. May be a component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Increases AURKB activity. Inhibits apoptosis induced by TGFB1. Overexpression induces swelling of mitochondria and reduces mitochondrial membrane potential.

Subcellular Location:

Membrane Single-pass type I membrane protein Mitochondrion Cytoplasm Cytoplasm cytoskeleton centrosome Cytoplasm cytoskeleton spindle Detected at the centrosome and along spindle fibers during prophase and metaphase. Detected at the midbody during telophase.

Protein Attributes:

Sequence length:

146

Sequence:

50:

100:

146:

LEQHLFWKFE | GIVVGVALVF | ACLVIIRQRQ | LDRKALEKVR | KQIESI

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Rn.91803

STRING:

10116.ENSRNOP00000060227

Pfam:

PF05439

KEGG:

rno:29439

Uniprot:

O88823

FOR

ELISA Kit for Rat Protein JTB

CLIA Kit for Rat Protein JTB

Polyclonal Antibody for Rat Protein JTB

Monoclonal Antibody for Rat Protein JTB

Protein for Rat Protein JTB

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"JTB: a novel membrane protein gene at 1q21 rearranged in a jumping translocation."
Hatakeyama S. , Osawa M. , Omine M. , Ishikawa F.
Oncogene18:2085-2090(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Prostate.

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