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Index > Protein center > Krt14(Gene name) > Mouse
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  • Krt14 (Gene name),
  • Keratin, type I cytoskeletal 14 (Protein name ),  K1C14_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Krt14(Krt1-14);
    Protein name:
    Keratin, type I cytoskeletal 14;
    Alternative:
    Keratin-14(K14);Cytokeratin-14(CK-14);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Heterotetramer of two type I and two type II keratins. keratin-14 associates with keratin-5. Interacts with TRADD and with keratin filaments. Associates with other type I keratins.
    Function:
    The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro.
    Subcellular Location:
    Cytoplasm Nucleus Expressed in both as a filamentous pattern.
    Protein Attributes:
    Sequence length:
    484
    Sequence:
    50:
    MATCSRQFTS | SSSMKGSCGI | GGGSSRMSSI | LAGGSCRAPS | TYGGMSVTSS | 
    100:
    RFSSGGACGI | GGGYGGSFSS | SSFGGGLGSG | FGGRFDGFGG | GFGGGLGGGF | 
    150:
    GGGLGGGLGG | GIGDGLLVGS | EKVTMQNLND | RLATYLDKVR | ALEEANTELE | 
    200:
    VKIRDWYQRQ | RPTEIKDYSP | YFKTIEDLKS | KILAATVDNA | NVLLQIDNAR | 
    250:
    LAADDFRTKF | ETEQSLRMSV | EADINGLRRV | LDELTLARAD | LEMQIESLKE | 
    300:
    ELAYLKKNHE | EEMASMRGQV | GGDVNVEMDA | APGVDLSRIL | NEMRDQYEKM | 
    350:
    AEKNRKDAEE | WFFSKTEELN | REVATNSELV | QSGKSEISEL | RRTMQNLEIE | 
    400:
    LQSQLSMKAS | LENNLEETKG | RYCMQLAQIQ | EMIGSVEEQL | AQLRCEMEQQ | 
    450:
    NQEYKILLDV | KTRLEQEIAT | YRRLLEGEDA | HLSSSQFSSS | SQFSSGSQSS | 
    484:
    RDVTSTNRQI | RTKVMDVHDG | KVVSTHEQVL | RTKN
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    Pfam:
    String:
    UniGene:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Keratin, type I cytoskeletal 14
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    E8857m
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    ELISA Kit for Mouse Keratin, type I cytoskeletal 14
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    Packing:
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    ELISA Kit for Mouse Keratin, type I cytoskeletal 14
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    ELISA Kit for Mouse Keratin, type I cytoskeletal 14
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    E8857b
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    ELISA Kit for Mouse Keratin, type I cytoskeletal 14
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    E8857h
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    MSDS:
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    Packing:
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    CLIA Kit for Mouse Keratin, type I cytoskeletal 14
    Cat.:
    U8857h
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Keratin, type I cytoskeletal 14
    Cat.:
    U8857b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Keratin, type I cytoskeletal 14
    Cat.:
    U8857c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Keratin, type I cytoskeletal 14
    Cat.:
    U8857r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Keratin, type I cytoskeletal 14
    Cat.:
    U8857m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Keratin, type I cytoskeletal 14
    Cat.:
    P8857Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Keratin, type I cytoskeletal 14
    Cat.:
    P8857Rb-r
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Keratin, type I cytoskeletal 14
    Cat.:
    P8857Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Keratin, type I cytoskeletal 14
    Polyclonal Antibody for Mouse Keratin, type I cytoskeletal 14
    Monoclonal Antibody for Mouse Keratin, type I cytoskeletal 14
    Monoclonal Antibody for Mouse Keratin, type I cytoskeletal 14
    Monoclonal Antibody for Mouse Keratin, type I cytoskeletal 14
    Monoclonal Antibody for Mouse Keratin, type I cytoskeletal 14
    Monoclonal Antibody for Mouse Keratin, type I cytoskeletal 14
    Protein for Mouse Keratin, type I cytoskeletal 14
    Protein for Mouse Keratin, type I cytoskeletal 14
    Protein for Mouse Keratin, type I cytoskeletal 14
    Protein for Mouse Keratin, type I cytoskeletal 14
    Protein for Mouse Keratin, type I cytoskeletal 14

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    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    2. 2.
      "Structural basis for heteromeric assembly and perinuclear organization of keratin filaments."
      Lee C.H. , Kim M.S. , Chung B.M. , Leahy D.J. , Coulombe P.A.
      Nat. Struct. Mol. Biol.19:707-715(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT;DISULFIDE BOND
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: FVB/N.
      tissue: Mammary tumor.
    4. 4.
      Lubec G. , Sunyer B. , Chen W.-Q.
      Submitted (2009-01) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 123-131; 201-207; 218-228; 322-334 AND 414-422;IDENTIFICATION BY MASS SPECTROMETRY
      strain: OF1.
      tissue: Hippocampus.
    5. 5.
      "Three cDNA sequences of mouse type I keratins: cellular localization of the mRNAs in normal and hyperproliferative tissues."
      Knapp B. , Rentrop M. , Schweizer J. , Winter H.
      J. Biol. Chem.262:938-945(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 126-484
    6. 6.
      "Keratin 17 modulates hair follicle cycling in a TNFalpha-dependent fashion."
      Tong X. , Coulombe P.A.
      Genes Dev.20:1353-1364(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TRADD
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