KCNAB1 ELISA Kit for Human(Homo sapiens) | EIAab.comKCNAB1 ELISA Kit for Human(Homo sapiens)

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KCNAB1 (Gene name),

Voltage-gated potassium channel subunit beta-1 (Protein name ), KCAB1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

KCNAB1(KCNA1B);

Protein name:

Voltage-gated potassium channel subunit beta-1;

Alternative:

Kv-beta-1;K(+) channel subunit beta-1;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Forms heteromultimeric complex with alpha subunits. Interacts with SQSTM1 (By similarity). Part of a complex containing KCNA1, KCNA4 and LGI1.

Function:

Accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit. All three isoforms alter the functional properties of Kv1.4 and Kv1.5. Isoform KvB1.2 has no effect on Kv1.1, Kv1.2 or Kv2.1.

Subcellular Location:

Cytoplasm

Protein Attributes:

Sequence length:

419

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

419:

NEIDNILRNK | PYSKKDYRS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Hs.654519

KEGG:

hsa:7881

MIM:

601141

String:

Q14722

Pfam:

PF00248

STRING:

9606.ENSP00000419952

SMR:

Q14722

Uniprot:

Q14722

FOR

ELISA Kit for Human Voltage-gated potassium channel subunit beta-1

CLIA Kit for Human Voltage-gated potassium channel subunit beta-1

Polyclonal Antibody for Human Voltage-gated potassium channel subunit beta-1

Monoclonal Antibody for Human Voltage-gated potassium channel subunit beta-1

Protein for Human Voltage-gated potassium channel subunit beta-1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"A novel K+ channel beta-subunit (hKv beta 1.3) is produced via alternative mRNA splicing."
England S.K. , Uebele V.N. , Kodali J. , Bennett P.B. , Tamkun M.M.
J. Biol. Chem.270:28531-28534(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM KVB1.3)
tissue: Heart left ventricle.
2.

"Molecular cloning and functional expression of a novel potassium channel beta-subunit from human atrium."
Majumder K. , De Biasi M. , Wang Z. , Wible B.A.
FEBS Lett.361:13-16(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM KVB1.2)
tissue: Heart atrium.
3.

"Characterization of a voltage-gated K+ channel beta subunit expressed in human heart."
England S.K. , Uebele V.N. , Shear H. , Kodali J. , Bennett P.B. , Tamkun M.M.
Proc. Natl. Acad. Sci. U.S.A.92:6309-6313(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM KVB1.2);TISSUE SPECIFICITY
tissue: Heart left ventricle.
4.

"Alternative splicing of the human Shaker K+ channel beta 1 gene and functional expression of the beta 2 gene product."
Mccormack K. , McCormack T. , Tanouye M.A. , Rudy B. , Stuehmer W.
FEBS Lett.370:32-36(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM KVB1.1)
tissue: Hippocampus.
5.

"Structural and functional characterization of human potassium channel subunit beta 1 (KCNA1B)."
Leicher T. , Roeper J. , Weber K. , Wang X. , Pongs O.
Neuropharmacology35:787-795(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM KVB1.1);TISSUE SPECIFICITY
tissue: Brain cortex.
6.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS KVB1.1; KVB1.2 AND KVB1.3)
tissue: Hippocampus.
tissue: Thymus.
tissue: Trachea.
7.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
8.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM KVB1.1)
tissue: Brain.
9.

"A novel beta subunit increases rate of inactivation of specific voltage-gated potassium channel alpha subunits."
Morales M.J. , Castellino R.C. , Crews A.L. , Rasmusson R.L. , Strauss H.C.
J. Biol. Chem.270:6272-6277(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 4-147 (ISOFORM KVB1.2)
tissue: Heart.

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