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Index > Protein center > Camk2a(Gene name) > Mouse
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  • Camk2a (Gene name),
  • Calcium/calmodulin-dependent protein kinase type II subunit alpha (Protein name ),  KCC2A_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Camk2a;
    Protein name:
    Calcium/calmodulin-dependent protein kinase type II subunit alpha(CaM kinase II subunit alpha;CaMK-II subunit alpha);
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    CAMK2 is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. Interacts with BAALC, MPDZ, SYN1, CAMK2N2 and SYNGAP1.
    Function:
    CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity.
    Subcellular Location:
    Isoform Alpha KAP Cytoplasm Cell junction synapse presynaptic cell membrane Cell junction synapse Postsynaptic lipid rafts.
    Protein Attributes:
    Sequence length:
    478
    Sequence:
    50:
    MATITCTRFT | EEYQLFEELG | KGAFSVVRRC | VKVLAGQEYA | AKIINTKKLS | 
    100:
    ARDHQKLERE | ARICRLLKHP | NIVRLHDSIS | EEGHHYLIFD | LVTGGELFED | 
    150:
    IVAREYYSEA | DASHCIQQIL | EAVLHCHQMG | VVHRDLKPEN | LLLASKLKGA | 
    200:
    AVKLADFGLA | IEVEGEQQAW | FGFAGTPGYL | SPEVLRKDPY | GKPVDLWACG | 
    250:
    VILYILLVGY | PPFWDEDQHR | LYQQIKAGAY | DFPSPEWDTV | TPEAKDLINK | 
    300:
    MLTINPSKRI | TAAEALKHPW | ISHRSTVASC | MHRQETVDCL | KKFNARRKLK | 
    350:
    GAILTTMLAT | RNFSGGKSGG | NKKNDGVKES | SESTNTTIED | EDTKVRKQEI | 
    400:
    IKVTEQLIEA | ISNGDFESYT | KMCDPGMTAF | EPEALGNLVE | GLDFHRFYFE | 
    450:
    NLWSRNSKPV | HTTILNPHIH | LMGDESACIA | YIRITQYLDA | GGIPRTAQSE | 
    478:
    ETRVWHRRDG | KWQIVHFHRS | GAPSVLPH
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    UniGene:
    KEGG:
    SMR:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse CaM kinase II subunit alpha
    Cat.:
    E0655h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse CaM kinase II subunit alpha
    Cat.:
    E0655r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse CaM kinase II subunit alpha
    Cat.:
    E0655m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse CaM kinase II subunit alpha
    Cat.:
    U0655r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse CaM kinase II subunit alpha
    Cat.:
    U0655h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse CaM kinase II subunit alpha
    Cat.:
    U0655m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse CaM kinase II subunit alpha
    Cat.:
    P0655Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse CaM kinase II subunit alpha
    Cat.:
    P0655Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse CaM kinase II subunit alpha
    Cat.:
    P0655Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse CaM kinase II subunit alpha
    Monoclonal Antibody for Mouse CaM kinase II subunit alpha
    Monoclonal Antibody for Mouse CaM kinase II subunit alpha
    Protein for Mouse CaM kinase II subunit alpha
    Protein for Mouse CaM kinase II subunit alpha
    Protein for Mouse CaM kinase II subunit alpha

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Sequence of the cDNA for the alpha subunit of calmodulin kinase II from mouse brain."
      Hanley R.M. , Payne M.E. , Cruzalegui F. , Christenson M.A. , Means A.R.
      Nucleic Acids Res.17:3992-3992(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: ICR.
      tissue: Brain.
    2. 2.
      "An alternative, nonkinase product of the brain-specifically expressed Ca2+/calmodulin-dependent kinase II alpha isoform gene in skeletal muscle."
      Bayer K.-U. , Loehler J. , Harbers K.
      Mol. Cell. Biol.16:29-36(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM ALPHA KAP)
      strain: BALB/c.
      tissue: Skeletal muscle.
    3. 3.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Hippocampus.
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Eye.
    5. 5.
      Lubec G. , Sunyer B. , Chen W.-Q.
      Submitted (2009-01) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 9-21; 33-42; 135-146; 260-267; 301-311; 329-344; 353-371; 397-405; 434-445 AND 470-478;IDENTIFICATION BY MASS SPECTROMETRY
      strain: OF1.
      tissue: Hippocampus.
    6. 6.
      "Comprehensive identification of phosphorylation sites in postsynaptic density preparations."
      Trinidad J.C. , Specht C.G. , Thalhammer A. , Schoepfer R. , Burlingame A.L.
      Mol. Cell. Proteomics5:914-922(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Brain.
    7. 7.
      "Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain."
      Ballif B.A. , Carey G.R. , Sunyaev S.R. , Gygi S.P.
      J. Proteome Res.7:311-318(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-13;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Brain.
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