Protein name:
Potassium voltage-gated channel subfamily A member 1 ;
Alternative:
RCK1 ;RBKI ;Voltage-gated potassium channel subunit Kv1.1 ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Heterotetramer of potassium channel proteins. Binds KCNAB2 (By similarity). Binds PDZ domains of DLG1, DLG2 and DLG4. Interacts with LGI1 within a complex containing LGI1, KCNA4 and KCNAB1.
Function:
Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.
Subcellular Location:
Membrane
Multi-pass membrane protein
Protein Attributes:
50:
MTVMSGENAD | EASAAPGHPQ | DGSYPRQADH | DDHECCERVV | INISGLRFET |
100:
QLKTLAQFPN | TLLGNPKKRM | RYFDPLRNEY | FFDRNRPSFD | AILYYYQSGG |
150:
RLRRPVNVPL | DMFSEEIKFY | ELGEEAMEKF | REDEGFIKEE | ERPLPEKEYQ |
200:
RQVWLLFEYP | ESSGPARVIA | IVSVMVILIS | IVIFCLETLP | ELKDDKDFTG |
250:
TIHRIDNTTV | IYTSNIFTDP | FFIVETLCII | WFSFELVVRF | FACPSKTDFF |
300:
KNIMNFIDIV | AIIPYFITLG | TEIAEQEGNQ | KGEQATSLAI | LRVIRLVRVF |
350:
RIFKLSRHSK | GLQILGQTLK | ASMRELGLLI | FFLFIGVILF | SSAVYFAEAE |
400:
EAESHFSSIP | DAFWWAVVSM | TTVGYGDMYP | VTIGGKIVGS | LCAIAGVLTI |
450:
ALPVPVIVSN | FNYFYHRETE | GEEQAQLLHV | SSPNLASDSD | LSRRSSSTIS |
495:
KSEYMEIEED | MNNSIAHYRQ | ANIRTGNCTA | TDQNCVNKSK | LLTDV
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
ELISA Kit for Rat Potassium voltage-gated channel subfamily A member 1
ELISA Kit for Rat Potassium voltage-gated channel subfamily A member 1
ELISA Kit for Rat Potassium voltage-gated channel subfamily A member 1
CLIA Kit for Rat Potassium voltage-gated channel subfamily A member 1
CLIA Kit for Rat Potassium voltage-gated channel subfamily A member 1
CLIA Kit for Rat Potassium voltage-gated channel subfamily A member 1
Polyclonal Antibody for Rat Potassium voltage-gated channel subfamily A member 1
Polyclonal Antibody for Rat Potassium voltage-gated channel subfamily A member 1
Polyclonal Antibody for Rat Potassium voltage-gated channel subfamily A member 1
Monoclonal Antibody for Rat Potassium voltage-gated channel subfamily A member 1
Monoclonal Antibody for Rat Potassium voltage-gated channel subfamily A member 1
Monoclonal Antibody for Rat Potassium voltage-gated channel subfamily A member 1
Protein for Rat Potassium voltage-gated channel subfamily A member 1
Protein for Rat Potassium voltage-gated channel subfamily A member 1
Protein for Rat Potassium voltage-gated channel subfamily A member 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Brain .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Brain .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : RNA EDITING OF POSITION 400
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH DLG1; DLG2 AND DLG4
5.
"The epilepsy-linked Lgi1 protein assembles into presynaptic Kv1 channels and inhibits inactivation by Kvbeta1."
Schulte U.
,
Thumfart J.-O.
,
Kloecker N.
,
Sailer C.A.
,
Bildl W.
,
Biniossek M.
,
Dehn D.
,
Deller T.
,
Eble S.
,
Abbass K.
,
Wangler T.
,
Knaus H.-G.
,
Fakler B.
Neuron49:697-706(2006)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH LGI1; KCNA4 AND KCNAB1
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS) OF 29-128;INTERACTION WITH KCNAB2;TETRAMERIZATION