Protein name:
Potassium voltage-gated channel subfamily A member 5 ;
Alternative:
RK4 ;RCK7 ;Voltage-gated potassium channel subunit Kv1.5 ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Heterotetramer of potassium channel proteins (By similarity). Interacts with DLG1, which enhances channel currents. Forms a ternary complex with DLG1 and CAV3. Interacts with UBE2I.
Function:
Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. This channel displays rapid activation and slow inactivation.
Subcellular Location:
Membrane
Multi-pass membrane protein
Protein Attributes:
50:
MEISLVPLEN | GSAMTLRGGG | EAGASCVQTP | RGECGCPPTS | GLNNQSKETL |
100:
LRGRTTLEDA | NQGGRPLPPM | AQELPQPRRL | SAEDEEGEGD | PGLGTVEEDQ |
150:
APQDAGSLHH | QRVLINISGL | RFETQLGTLA | QFPNTLLGDP | AKRLHYFDPL |
200:
RNEYFFDRNR | PSFDGILYYY | QSGGRLRRPV | NVSLDVFADE | IRFYQLGDEA |
250:
MERFREDEGF | IKEEEKPLPR | NEFQRQVWLI | FEYPESSGSA | RAIAIVSVLV |
300:
ILISIITFCL | ETLPEFRDER | ELLRHPPVPP | QPPAPAPGIN | GSVSGALSSG |
350:
PTVAPLLPRT | LADPFFIVET | TCVIWFTFEL | LVRFFACPSK | AEFSRNIMNI |
400:
IDVVAIFPYF | ITLGTELAEQ | QPGGGGQNGQ | QAMSLAILRV | IRLVRVFRIF |
450:
KLSRHSKGLQ | ILGKTLQASM | RELGLLIFFL | FIGVILFSSA | VYFAEADNHG |
500:
SHFSSIPDAF | WWAVVTMTTV | GYGDMRPITV | GGKIVGSLCA | IAGVLTIALP |
550:
VPVIVSNFNY | FYHRETDHEE | QAALKEEQGN | QRRESGLDTG | GQRKVSCSKA |
600:
SFCKTGGSLE | SSDSIRRGSC | PLEKCHLKAK | SNVDLRRSLY | ALCLDTSRET |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rabbit
Mouse
Rat
ELISA Kit for Rat Potassium voltage-gated channel subfamily A member 5
ELISA Kit for Rat Potassium voltage-gated channel subfamily A member 5
ELISA Kit for Rat Potassium voltage-gated channel subfamily A member 5
ELISA Kit for Rat Potassium voltage-gated channel subfamily A member 5
CLIA Kit for Rat Potassium voltage-gated channel subfamily A member 5
CLIA Kit for Rat Potassium voltage-gated channel subfamily A member 5
CLIA Kit for Rat Potassium voltage-gated channel subfamily A member 5
CLIA Kit for Rat Potassium voltage-gated channel subfamily A member 5
Polyclonal Antibody for Rat Potassium voltage-gated channel subfamily A member 5
Polyclonal Antibody for Rat Potassium voltage-gated channel subfamily A member 5
Polyclonal Antibody for Rat Potassium voltage-gated channel subfamily A member 5
Polyclonal Antibody for Rat Potassium voltage-gated channel subfamily A member 5
Monoclonal Antibody for Rat Potassium voltage-gated channel subfamily A member 5
Monoclonal Antibody for Rat Potassium voltage-gated channel subfamily A member 5
Monoclonal Antibody for Rat Potassium voltage-gated channel subfamily A member 5
Monoclonal Antibody for Rat Potassium voltage-gated channel subfamily A member 5
Protein for Rat Potassium voltage-gated channel subfamily A member 5
Protein for Rat Potassium voltage-gated channel subfamily A member 5
Protein for Rat Potassium voltage-gated channel subfamily A member 5
Protein for Rat Potassium voltage-gated channel subfamily A member 5
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Cloning and expression of cDNA and genomic clones encoding three delayed rectifier potassium channels in rat brain."
Swanson R.
,
Marshall J.
,
Smith J.
,
Williams J.
,
Boyle M.B.
,
Folander K.
,
Luneau C.J.
,
Antanavage J.
,
Oliva C.
,
Buhrow S.A.
,
Bennett C.
,
Stein R.B.
,
Kaczmarek L.M.
Neuron4:929-939(1990)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
tissue :
Brain .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA];TISSUE SPECIFICITY
strain :
Sprague-Dawley .
tissue :
Heart .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-15
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH DLG1;MUTAGENESIS OF 600-THR--LEU-602
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH DLG1 AND CAV3;FUNCTION IN CELL EXCITATION