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Index > Protein center > KCNC3(Gene name) > Human
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  • KCNC3 (Gene name),
  • Potassium voltage-gated channel subfamily C member 3 (Protein name ),  KCNC3_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    KCNC3;
    Protein name:
    Potassium voltage-gated channel subfamily C member 3;
    Alternative:
    Voltage-gated potassium channel subunit Kv3.3;KSHIIID;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Heterotetramer of potassium channel proteins.
    Function:
    This protein mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.
    Subcellular Location:
    Membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    757
    Sequence:
    50:
    MLSSVCVSSF | RGRQGASKQQ | PAPPPQPPES | PPPPPLPPQQ | QQPAQPGPAA | 
    100:
    SPAGPPAPRG | PGDRRAEPCP | GLPAAAMGRH | GGGGGDSGKI | VINVGGVRHE | 
    150:
    TYRSTLRTLP | GTRLAGLTEP | EAAARFDYDP | GADEFFFDRH | PGVFAYVLNY | 
    200:
    YRTGKLHCPA | DVCGPLFEEE | LGFWGIDETD | VEACCWMTYR | QHRDAEEALD | 
    250:
    SFEAPDPAGA | ANAANAAGAH | DGGLDDEAGA | GGGGLDGAGG | ELKRLCFQDA | 
    300:
    GGGAGGPPGG | AGGAGGTWWR | RWQPRVWALF | EDPYSSRAAR | YVAFASLFFI | 
    350:
    LISITTFCLE | THEGFIHISN | KTVTQASPIP | GAPPENITNV | EVETEPFLTY | 
    400:
    VEGVCVVWFT | FEFLMRITFC | PDKVEFLKSS | LNIIDCVAIL | PFYLEVGLSG | 
    450:
    LSSKAAKDVL | GFLRVVRFVR | ILRIFKLTRH | FVGLRVLGHT | LRASTNEFLL | 
    500:
    LIIFLALGVL | IFATMIYYAE | RIGADPDDIL | GSNHTYFKNI | PIGFWWAVVT | 
    550:
    MTTLGYGDMY | PKTWSGMLVG | ALCALAGVLT | IAMPVPVIVN | NFGMYYSLAM | 
    600:
    AKQKLPKKKN | KHIPRPPQPG | SPNYCKPDPP | PPPPPHPHHG | SGGISPPPPI | 
    650:
    TPPSMGVTVA | GAYPAGPHTH | PGLLRGGAGG | LGIMGLPPLP | APGEPCPLAQ | 
    700:
    EEVIEINRAD | PRPNGDPAAA | ALAHEDCPAI | DQPAMSPEDK | SPITPGSRGR | 
    750:
    YSRDRACFLL | TDYAPSPDGS | IRKATGAPPL | PPQDWRKPGP | PSFLPDLNAN | 
    757:
    AAAWISP
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    SMR:
    KEGG:
    Pfam:
    Pfam:
    String:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Potassium voltage-gated channel subfamily C member 3
    ELISA Kit for Human Potassium voltage-gated channel subfamily C member 3
    ELISA Kit for Human Potassium voltage-gated channel subfamily C member 3
    CLIA Kit for Human Potassium voltage-gated channel subfamily C member 3
    CLIA Kit for Human Potassium voltage-gated channel subfamily C member 3
    CLIA Kit for Human Potassium voltage-gated channel subfamily C member 3
    Polyclonal Antibody for Human Potassium voltage-gated channel subfamily C member 3
    Polyclonal Antibody for Human Potassium voltage-gated channel subfamily C member 3
    Polyclonal Antibody for Human Potassium voltage-gated channel subfamily C member 3
    Monoclonal Antibody for Human Potassium voltage-gated channel subfamily C member 3
    Monoclonal Antibody for Human Potassium voltage-gated channel subfamily C member 3
    Monoclonal Antibody for Human Potassium voltage-gated channel subfamily C member 3
    Protein for Human Potassium voltage-gated channel subfamily C member 3
    Protein for Human Potassium voltage-gated channel subfamily C member 3
    Protein for Human Potassium voltage-gated channel subfamily C member 3

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Kv3.3 potassium channels in lens epithelium and corneal endothelium."
      Rae J.L. , Shepard A.R.
      Exp. Eye Res.70:339-348(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Lens epithelium.
    2. 2.
      "The DNA sequence and biology of human chromosome 19."
      Grimwood J. , Gordon L.A. , Olsen A.S. , Terry A. , Schmutz J. , Lamerdin J.E. , Hellsten U. , Goodstein D. , Couronne O. , Tran-Gyamfi M. , Aerts A. , Altherr M. , Ashworth L. , Bajorek E. , Black S. , Branscomb E. , Caenepeel S. , Carrano A.V. , more...
      Nature428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      "A human chromosome 19 Shaw type potassium channel gene."
      Lee J.E. , Garbutt J.H. , Phillips K.L. , Roses A.D.
      Submitted (1992-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 291-651
    4. 4.
      "Mutations in voltage-gated potassium channel KCNC3 cause degenerative and developmental nervous system phenotypes."
      Waters M.F. , Minassian N.A. , Stevanin G. , Figueroa K.P. , Bannister J.P.A. , Nolte D. , Mock A.F. , Evidente V.G.H. , Fee D.B. , Mueller U. , Duerr A. , Brice A. , Papazian D.M. , Pulst S.M.
      Nat. Genet.38:447-451(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS SCA13 HIS-420 AND LEU-448;CHARACTERIZATION OF VARIANTS SCA13 HIS-420 AND LEU-448
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