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Index > Protein center > KCNC4(Gene name) > Human
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  • KCNC4 (Gene name),
  • Potassium voltage-gated channel subfamily C member 4 (Protein name ),  KCNC4_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    KCNC4;
    Protein name:
    Potassium voltage-gated channel subfamily C member 4;
    Alternative:
    Voltage-gated potassium channel subunit Kv3.4;KSHIIIC;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homotetramer (Probable). Heterotetramer of potassium channel proteins.
    Function:
    This protein mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.
    Subcellular Location:
    Membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    635
    Sequence:
    50:
    MISSVCVSSY | RGRKSGNKPP | SKTCLKEEMA | KGEASEKIII | NVGGTRHETY | 
    100:
    RSTLRTLPGT | RLAWLADPDG | GGRPETDGGG | VGSSGSSGGG | GCEFFFDRHP | 
    150:
    GVFAYVLNYY | RTGKLHCPAD | VCGPLFEEEL | TFWGIDETDV | EPCCWMTYRQ | 
    200:
    HRDAEEALDI | FESPDGGGSG | AGPSDEAGDD | ERELALQRLG | PHEGGAGHGA | 
    250:
    GSGGCRGWQP | RMWALFEDPY | SSRAARVVAF | ASLFFILVSI | TTFCLETHEA | 
    300:
    FNIDRNVTEI | LRVGNITSVH | FRREVETEPI | LTYIEGVCVL | WFTLEFLVRI | 
    350:
    VCCPDTLDFV | KNLLNIIDFV | AILPFYLEVG | LSGLSSKAAR | DVLGFLRVVR | 
    400:
    FVRILRIFKL | TRHFVGLRVL | GHTLRASTNE | FLLLIIFLAL | GVLIFATMIY | 
    450:
    YAERIGARPS | DPRGNDHTDF | KNIPIGFWWA | VVTMTTLGYG | DMYPKTWSGM | 
    500:
    LVGALCALAG | VLTIAMPVPV | IVNNFGMYYS | LAMAKQKLPK | KRKKHVPRPA | 
    550:
    QLESPMYCKS | EETSPRDSTC | SDTSPPAREE | GMIERKRADS | KQNGDANAVL | 
    600:
    SDEEGAGLTQ | PLASSPTPEE | RRALRRSTTR | DRNKKAAACF | LLSTGDYACA | 
    635:
    DGSVRKGTFV | LRDLPLQHSP | EAACPPTAGT | LFLPH
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    MIM:
    SMR:
    String:
    UniGene:
    Pfam:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Potassium voltage-gated channel subfamily C member 4
    ELISA Kit for Human Potassium voltage-gated channel subfamily C member 4
    ELISA Kit for Human Potassium voltage-gated channel subfamily C member 4
    CLIA Kit for Human Potassium voltage-gated channel subfamily C member 4
    CLIA Kit for Human Potassium voltage-gated channel subfamily C member 4
    CLIA Kit for Human Potassium voltage-gated channel subfamily C member 4
    Polyclonal Antibody for Human Potassium voltage-gated channel subfamily C member 4
    Polyclonal Antibody for Human Potassium voltage-gated channel subfamily C member 4
    Polyclonal Antibody for Human Potassium voltage-gated channel subfamily C member 4
    Monoclonal Antibody for Human Potassium voltage-gated channel subfamily C member 4
    Monoclonal Antibody for Human Potassium voltage-gated channel subfamily C member 4
    Monoclonal Antibody for Human Potassium voltage-gated channel subfamily C member 4
    Protein for Human Potassium voltage-gated channel subfamily C member 4
    Protein for Human Potassium voltage-gated channel subfamily C member 4
    Protein for Human Potassium voltage-gated channel subfamily C member 4

    R&D Technical Data
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    Linearity
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    References
    1. 1.
      "Cloning of ShIII (Shaw-like) cDNAs encoding a novel high-voltage-activating, TEA-sensitive, type-A K+ channel."
      de Miera E.V.-S. , Moreno H. , Fruhling D. , Kentros C. , Rudy B.
      Proc. R. Soc. B248:9-18(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
      tissue: Brain.
    2. 2.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 166-635 (ISOFORM 1)
      tissue: Brain.
    4. 4.
      "Elimination of rapid potassium channel inactivation by phosphorylation of the inactivation gate."
      Covarrubias M. , Wei A. , Salkoff L. , Vyas T.B.
      Neuron13:1403-1412(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-15 AND SER-21;MUTAGENESIS OF SER-15 AND SER-21
    5. 5.
      "Interactions between multiple phosphorylation sites in the inactivation particle of a K+ channel. Insights into the molecular mechanism of protein kinase C action."
      Beck E.J. , Sorensen R.G. , Slater S.J. , Covarrubias M.
      J. Gen. Physiol.112:71-84(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-8 AND SER-9;MUTAGENESIS OF SER-8; SER-9; SER-15 AND SER-21
    6. 6.
      "NMR structure of inactivation gates from mammalian voltage-dependent potassium channels."
      Antz C. , Geyer M. , Fakler B. , Schott M.K. , Guy H.R. , Frank R. , Ruppersberg J.P. , Kalbitzer H.R.
      Nature385:272-275(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 1-30
    7. 7.
      "Control of K+ channel gating by protein phosphorylation: structural switches of the inactivation gate."
      Antz C. , Bauer T. , Kalbacher H. , Frank R. , Covarrubias M. , Kalbitzer H.R. , Ruppersberg J.P. , Baukrowitz T. , Fakler B.
      Nat. Struct. Biol.6:146-150(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 1-30
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