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Index > Protein center > Kcne1(Gene name) > Rat
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  • Kcne1 (Gene name),
  • Potassium voltage-gated channel subfamily E member 1 (Protein name ),  KCNE1_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Kcne1;
    Protein name:
    Potassium voltage-gated channel subfamily E member 1;
    Alternative:
    IKs producing slow voltage-gated potassium channel subunit beta Mink;Delayed rectifier potassium channel subunit IsK;Minimal potassium channel;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Associates with KCNQ1/KVLQT1 and KCNH2/HERG.
    Function:
    Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNQ1/KVLQT1 is proposed to form the slowly activating delayed rectifier cardiac potassium (IKs) channel. The outward current reaches its steady state only after 50 seconds. Assembled with KCNH2/HERG may modulate the rapidly activating component of the delayed rectifying potassium current in heart (IKr).
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    130
    Sequence:
    50:
    MALSNSTTVL | PFLASLWQET | DEPGGNMSAD | LARRSQLRDD | SKLEALYILM | 
    100:
    VLGFFGFFTL | GIMLSYIRSK | KLEHSHDPFN | VYIESDAWQE | KGKALFQARV | 
    130:
    LESFRACYVI | ENQAAVEQPA | THLPELKPLS | 
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    Pfam:
    KEGG:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Potassium voltage-gated channel subfamily E member 1
    ELISA Kit for Rat Potassium voltage-gated channel subfamily E member 1
    ELISA Kit for Rat Potassium voltage-gated channel subfamily E member 1
    ELISA Kit for Rat Potassium voltage-gated channel subfamily E member 1
    ELISA Kit for Rat Potassium voltage-gated channel subfamily E member 1
    CLIA Kit for Rat Potassium voltage-gated channel subfamily E member 1
    CLIA Kit for Rat Potassium voltage-gated channel subfamily E member 1
    CLIA Kit for Rat Potassium voltage-gated channel subfamily E member 1
    CLIA Kit for Rat Potassium voltage-gated channel subfamily E member 1
    CLIA Kit for Rat Potassium voltage-gated channel subfamily E member 1
    Polyclonal Antibody for Rat Potassium voltage-gated channel subfamily E member 1
    Polyclonal Antibody for Rat Potassium voltage-gated channel subfamily E member 1
    Polyclonal Antibody for Rat Potassium voltage-gated channel subfamily E member 1
    Polyclonal Antibody for Rat Potassium voltage-gated channel subfamily E member 1
    Polyclonal Antibody for Rat Potassium voltage-gated channel subfamily E member 1
    Monoclonal Antibody for Rat Potassium voltage-gated channel subfamily E member 1
    Monoclonal Antibody for Rat Potassium voltage-gated channel subfamily E member 1
    Monoclonal Antibody for Rat Potassium voltage-gated channel subfamily E member 1
    Monoclonal Antibody for Rat Potassium voltage-gated channel subfamily E member 1
    Monoclonal Antibody for Rat Potassium voltage-gated channel subfamily E member 1
    Protein for Rat Potassium voltage-gated channel subfamily E member 1
    Protein for Rat Potassium voltage-gated channel subfamily E member 1
    Protein for Rat Potassium voltage-gated channel subfamily E member 1
    Protein for Rat Potassium voltage-gated channel subfamily E member 1
    Protein for Rat Potassium voltage-gated channel subfamily E member 1

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Cloning of a membrane protein that induces a slow voltage-gated potassium current."
      Takumi T. , Ohkubo H. , Nakanishi S.
      Science242:1042-1045(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Kidney.
    2. 2.
      "Cloning and expression of the delayed-rectifier IsK channel from neonatal rat heart and diethylstilbestrol-primed rat uterus."
      Folander K. , Smith J.S. , Antanavage J. , Bennett C. , Stein R.B. , Swanson R.
      Proc. Natl. Acad. Sci. U.S.A.87:2975-2979(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Heart.
    3. 3.
      "Estrogen induction of a small, putative K+ channel mRNA in rat uterus."
      Pragnell M. , Snay K.J. , Trimmer J.S. , Maclusky N.J. , Naftolin F. , Kaczmarek L.K. , Boyle M.B.
      Neuron4:807-812(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE
      tissue: Uterus.
    4. 4.
      "Characterization of gene organization and generation of heterogeneous mRNA species of rat ISK protein."
      Iwai M. , Masu M. , Tsuchida K. , Mori T. , Ohkubo H. , Nakanishi S.
      J. Biochem.108:200-206(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE
    5. 5.
      "An amino acid mutation in a potassium channel that prevents inhibition by protein kinase C."
      Busch A.E. , Varnum M.D. , North R.A. , Adelman J.P.
      Science255:1705-1707(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MUTAGENESIS OF SER-103
    6. 6.
      "Subunit composition of minK potassium channels."
      Wang K.-W. , Goldstein S.A.N.
      Neuron14:1303-1309(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MUTAGENESIS OF ASP-77
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