Protein name:
Potassium voltage-gated channel subfamily E member 2 ;
Alternative:
Minimum potassium ion channel-related peptide 1 ;MinK-related peptide 1 ;Potassium channel subunit beta MiRP1 ;
Organism:
Rabbit (Oryctolagus cuniculus).
General Annotation
Sub Unit:
Associates with KCNH2/ERG1 (By similarity). May associate with KCNQ1/KVLQT1, KCNQ2 and KCNQ3. Associates with HCN1 and probably HCN2.
Function:
Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Associated with KCNH2/HERG is proposed to form the rapidly activating component of the delayed rectifying potassium current in heart (IKr). May associate with KCNQ2 and/or KCNQ3 and modulate the native M-type current. May associate with KCNQ1/KCLQT1 and elicit a voltage-independent current.
Subcellular Location:
Membrane
Single-pass type I membrane protein
Protein Attributes:
50:
AENFYYVILY | LMVMIGMFSF | IIVAILVSTV | KSKRREHSND | PYHQYIVEDW |
71:
QEKYKSQILH | FEEAKATIHE | N
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rabbit
Mouse
Human
Rat
ELISA Kit for Rabbit Potassium voltage-gated channel subfamily E member 2
ELISA Kit for Rabbit Potassium voltage-gated channel subfamily E member 2
ELISA Kit for Rabbit Potassium voltage-gated channel subfamily E member 2
ELISA Kit for Rabbit Potassium voltage-gated channel subfamily E member 2
CLIA Kit for Rabbit Potassium voltage-gated channel subfamily E member 2
CLIA Kit for Rabbit Potassium voltage-gated channel subfamily E member 2
CLIA Kit for Rabbit Potassium voltage-gated channel subfamily E member 2
CLIA Kit for Rabbit Potassium voltage-gated channel subfamily E member 2
Polyclonal Antibody for Rabbit Potassium voltage-gated channel subfamily E member 2
Polyclonal Antibody for Rabbit Potassium voltage-gated channel subfamily E member 2
Polyclonal Antibody for Rabbit Potassium voltage-gated channel subfamily E member 2
Polyclonal Antibody for Rabbit Potassium voltage-gated channel subfamily E member 2
Monoclonal Antibody for Rabbit Potassium voltage-gated channel subfamily E member 2
Monoclonal Antibody for Rabbit Potassium voltage-gated channel subfamily E member 2
Monoclonal Antibody for Rabbit Potassium voltage-gated channel subfamily E member 2
Monoclonal Antibody for Rabbit Potassium voltage-gated channel subfamily E member 2
Protein for Rabbit Potassium voltage-gated channel subfamily E member 2
Protein for Rabbit Potassium voltage-gated channel subfamily E member 2
Protein for Rabbit Potassium voltage-gated channel subfamily E member 2
Protein for Rabbit Potassium voltage-gated channel subfamily E member 2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"MinK-related peptide 1: a beta subunit for the HCN ion channel subunit family enhances expression and speeds activation."
Yu H.
,
Wu J.
,
Potapova I.
,
Wymore R.T.
,
Holmes B.
,
Zuckerman J.
,
Pan Z.
,
Wang H.
,
Shi W.
,
Robinson R.B.
,
El-Maghrabi M.R.
,
Benjamin W.
,
Dixon J.E.
,
McKinnon D.
,
Cohen I.S.
,
Wymore R.
Circ. Res.88:E84-E87(2001)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
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Cited for : NUCLEOTIDE SEQUENCE [MRNA]