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Index > Protein center > Kcnh1(Gene name) > Rat
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  • Kcnh1 (Gene name),
  • Potassium voltage-gated channel subfamily H member 1 (Protein name ),  KCNH1_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    Kcnh1(Eag);
    Protein name:
    Potassium voltage-gated channel subfamily H member 1;
    Alternative:
    Voltage-gated potassium channel subunit Kv10.1;Ether-a-go-go potassium channel 1(EAG channel 1;EAG1;r-eag);
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits. Heteromultimer with KCNH5/EAG2 (By similarity). Interacts with ALG10B.
    Function:
    Pore-forming (alpha) subunit of voltage-gated non-inactivating delayed rectifier potassium channel. Channel properties may be modulated by cAMP and subunit assembly. Mediates IK(NI) current in myoblasts.
    Subcellular Location:
    Membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    962
    Sequence:
    50:
    MTMAGGRRGL | VAPQNTFLEN | IVRRSNDTNF | VLGNAQIVDW | PIVYSNDGFC | 
    100:
    KLSGYHRAEV | MQKSSACSFM | YGELTDKDTV | EKVRQTFENY | EMNSFEILMY | 
    150:
    KKNRTPVWFF | VKIAPIRNEQ | DKVVLFLCTF | SDITAFKQPI | EDDSCKGWGK | 
    200:
    FARLTRALTS | SRGVLQQLAP | SVQKGENVHK | HSRLAEVLQL | GSDILPQYKQ | 
    250:
    EAPKTPPHII | LHYCVFKTTW | DWIILILTFY | TAILVPYNVS | FKTRQNNVAW | 
    300:
    LVVDSIVDVI | FLVDIVLNFH | TTFVGPAGEV | ISDPKLIRMN | YLKTWFVIDL | 
    350:
    LSCLPYDVIN | AFENVDEGIS | SLFSSLKVVR | LLRLGRVARK | LDHYIEYGAA | 
    400:
    VLVLLVCVFG | LAAHWMACIW | YSIGDYEIFD | EDTKTIRNNS | WLYQLALDIG | 
    450:
    TPYQFNGSGS | GKWEGGPSKN | SVYISSLYFT | MTSLTSVGFG | NIAPSTDIEK | 
    500:
    IFAVAIMMIG | SLLYATIFGN | VTTIFQQMYA | NTNRYHEMLN | SVRDFLKLYQ | 
    550:
    VPKGLSERVM | DYIVSTWSMS | RGIDTEKVLQ | ICPKDMRADI | CVHLNRKVFK | 
    600:
    EHPAFRLASD | GCLRALAMEF | QTVHCAPGDL | IYHAGESVDS | LCFVVSGSLE | 
    650:
    VIQDDEVVAI | LGKGDVFGDV | FWKEATLAQS | CANVRALTYC | DLHVIKRDAL | 
    700:
    QKVLEFYTAF | SHSFSRNLIL | TYNLRKRIVF | RKISDVKREE | EERMKRKNEA | 
    750:
    PLILPPDHPV | RRLFQRFRQQ | KEARLAAERG | GRDLDDLDVE | KGNALTDHTS | 
    800:
    ANHSLVKASV | VTVRESPATP | VSFQAASTST | VSDHAKLHAP | GSECLGPKAG | 
    850:
    GGDPAKRKGW | ARFKDACGKG | EDWNKVSKAE | SMETLPERTK | ASGEATLKKT | 
    900:
    DSCDSGITKS | DLRLDNVGEA | RSPQDRSPIL | AEVKHSFYPI | PEQTLQATVL | 
    950:
    EVKHELKEDI | KALNAKMTSI | EKQLSEILRI | LMSRGSSQSP | QDTCEVSRPQ | 
    962:
    SPESDRDIFG | AS
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    KEGG:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Potassium voltage-gated channel subfamily H member 1
    ELISA Kit for Rat Potassium voltage-gated channel subfamily H member 1
    ELISA Kit for Rat Potassium voltage-gated channel subfamily H member 1
    ELISA Kit for Rat Potassium voltage-gated channel subfamily H member 1
    CLIA Kit for Rat Potassium voltage-gated channel subfamily H member 1
    CLIA Kit for Rat Potassium voltage-gated channel subfamily H member 1
    CLIA Kit for Rat Potassium voltage-gated channel subfamily H member 1
    CLIA Kit for Rat Potassium voltage-gated channel subfamily H member 1
    Polyclonal Antibody for Rat Potassium voltage-gated channel subfamily H member 1
    Polyclonal Antibody for Rat Potassium voltage-gated channel subfamily H member 1
    Polyclonal Antibody for Rat Potassium voltage-gated channel subfamily H member 1
    Polyclonal Antibody for Rat Potassium voltage-gated channel subfamily H member 1
    Monoclonal Antibody for Rat Potassium voltage-gated channel subfamily H member 1
    Monoclonal Antibody for Rat Potassium voltage-gated channel subfamily H member 1
    Monoclonal Antibody for Rat Potassium voltage-gated channel subfamily H member 1
    Monoclonal Antibody for Rat Potassium voltage-gated channel subfamily H member 1
    Protein for Rat Potassium voltage-gated channel subfamily H member 1
    Protein for Rat Potassium voltage-gated channel subfamily H member 1
    Protein for Rat Potassium voltage-gated channel subfamily H member 1
    Protein for Rat Potassium voltage-gated channel subfamily H member 1

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    Precision
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    Linearity
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    References
    1. 1.
      "Functional expression of a rat homologue of the voltage gated ether a go-go potassium channel reveals differences in selectivity and activation kinetics between the Drosophila channel and its mammalian counterpart."
      Ludwig J. , Terlau H. , Wunder F. , Brueggemann A. , Pardo L.A. , Marquardt A. , Stuehmer W. , Pongs O.
      EMBO J.13:4451-4458(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Cerebellum.
    2. 2.
      "Carboxy-terminal domain mediates assembly of the voltage-gated rat ether-a-go-go potassium channel."
      Ludwig J. , Owen D. , Pongs O.
      EMBO J.16:6337-6345(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DOMAIN CAD
    3. 3.
      "KCR1, a membrane protein that facilitates functional expression of non-inactivating K+ currents associates with rat EAG voltage-dependent K+ channels."
      Hoshi N. , Takahashi H. , Shahidullah M. , Yokoyama S. , Higashida H.
      J. Biol. Chem.273:23080-23085(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ALG10B
      strain: Wistar.
      tissue: Cerebellum.
    4. 4.
      "Expression of mRNA for voltage-dependent and inward-rectifying K channels in GH3/B6 cells and rat pituitary."
      Wulfsen I. , Hauber H.-P. , Schiemann D. , Bauer C.K. , Schwarz J.R.
      J. Neuroendocrinol.12:263-272(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
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