Gene name:
Kcnh2 (Erg;Merg1) ;
Protein name:
Potassium voltage-gated channel subfamily H member 2 ;
Alternative:
Voltage-gated potassium channel subunit Kv11.1 ;Ether-a-go-go-related gene potassium channel 1 (ERG-1;Eag-related protein 1;Ether-a-go-go-related protein 1;MERG) ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits. Heteromultimer with KCNH6/ERG2, KCNH7/ERG3, KCNE1 and KCNE2. Interacts with ALG10B.
Function:
Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr).
Subcellular Location:
Membrane
Multi-pass membrane protein
Protein Attributes:
50:
MPVRRGHVAP | QNTFLDTIIR | KFEGQSRKFI | IANARVENCA | VIYCNDGFCE |
100:
LCGYSRAEVM | QRPCTCDFLH | GPRTQRRAAA | QIAQALLGAE | ERKVEIAFYR |
150:
KDGSCFLCLV | DVVPVKNEDG | AVIMFILNFE | VVMEKDMVGS | PAHDTNHRGP |
200:
STSWLASGRA | KTFRLKLPAL | LALTARESSV | RTGSMHSAGA | PGAVVVDVDL |
250:
TPAAPSSESL | ALDEVSAMDN | HVAGLGPAEE | RRALVGPGSA | SPVASIRGPH |
300:
PSPRAQSLNP | DASGSSCSLA | RTRSRESCAS | VRRASSADDI | EAMRAGALPP |
350:
PPRHASTGAM | HPLRSGLLNS | TSDSDLVRYR | TISKIPQITL | NFVDLKGDPF |
400:
LASPTSDREI | IAPKIKERTH | NVTEKVTQVL | SLGADVLPEY | KLQAPRIHRW |
450:
TILHYSPFKA | VWDWLILLLV | IYTAVFTPYS | AAFLLKETED | GSQAPDCGYA |
500:
CQPLAVVDLI | VDIMFIVDIL | INFRTTYVNA | NEEVVSHPGR | IAVHYFKGWF |
550:
LIDMVAAIPF | DLLIFGSGSE | ELIGLLKTAR | LLRLVRVARK | LDRYSEYGAA |
600:
VLFLLMCTFA | LIAHWLACIW | YAIGNMEQPH | MDSHIGWLHN | LGDQIGKPYN |
650:
SSGLGGPSIK | DKYVTALYFT | FSSLTSVGFG | NVSPNTNSEK | IFSICVMLIG |
700:
SLMYASIFGN | VSAIIQRLYS | GTARYHTQML | RVREFIRFHQ | IPNPLRQRLE |
750:
EYFQHAWSYT | NGIDMNAVLK | GFPECLQADI | CLHLNRSLLQ | HCKPFRGATK |
800:
GCLRALAMKF | KTTHAPPGDT | LVHAGDLLTA | LYFISRGSIE | ILRGDVVVAI |
850:
LGKNDIFGEP | LNLYARPGKS | NGDVRALTYC | DLHKIHRDDL | LEVLDMYPEF |
900:
SDHFWSSLEI | TFNLRDTNMI | PGSPGSAELE | SGFNRQRKRK | LSFRRRTDKD |
950:
TEQPGEVSAL | GQGPARVGPG | PSCRGQPGGP | WGESPSSGPS | SPESSEDEGP |
1000:
GRSSSPLRLV | PFSSPRPPGD | PPGGEPLTED | GEKSDTCNPL | SGAFSGVSNI |
1050:
FSFWGDSRGR | QYQELPRCPA | PAPSLLNIPL | SSPGRRSRGD | VESRLDALQR |
1100:
QLNRLETRLS | ADMATVLQLL | QRQMTLVPPA | YSAVTTPGPG | PTSASPLLPV |
1150:
GPVPTLTLDS | LSQVSQFVAF | EELPAGAPEL | PQDGPTRRLS | LPGQLGALTS |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Chicken
Mouse
Dog
Pig
Human
Rat
Rabbit
ELISA Kit for Mouse Potassium voltage-gated channel subfamily H member 2
ELISA Kit for Mouse Potassium voltage-gated channel subfamily H member 2
ELISA Kit for Mouse Potassium voltage-gated channel subfamily H member 2
ELISA Kit for Mouse Potassium voltage-gated channel subfamily H member 2
ELISA Kit for Mouse Potassium voltage-gated channel subfamily H member 2
ELISA Kit for Mouse Potassium voltage-gated channel subfamily H member 2
ELISA Kit for Mouse Potassium voltage-gated channel subfamily H member 2
CLIA Kit for Mouse Potassium voltage-gated channel subfamily H member 2
CLIA Kit for Mouse Potassium voltage-gated channel subfamily H member 2
CLIA Kit for Mouse Potassium voltage-gated channel subfamily H member 2
CLIA Kit for Mouse Potassium voltage-gated channel subfamily H member 2
CLIA Kit for Mouse Potassium voltage-gated channel subfamily H member 2
CLIA Kit for Mouse Potassium voltage-gated channel subfamily H member 2
CLIA Kit for Mouse Potassium voltage-gated channel subfamily H member 2
Polyclonal Antibody for Mouse Potassium voltage-gated channel subfamily H member 2
Polyclonal Antibody for Mouse Potassium voltage-gated channel subfamily H member 2
Polyclonal Antibody for Mouse Potassium voltage-gated channel subfamily H member 2
Polyclonal Antibody for Mouse Potassium voltage-gated channel subfamily H member 2
Polyclonal Antibody for Mouse Potassium voltage-gated channel subfamily H member 2
Polyclonal Antibody for Mouse Potassium voltage-gated channel subfamily H member 2
Polyclonal Antibody for Mouse Potassium voltage-gated channel subfamily H member 2
Monoclonal Antibody for Mouse Potassium voltage-gated channel subfamily H member 2
Monoclonal Antibody for Mouse Potassium voltage-gated channel subfamily H member 2
Monoclonal Antibody for Mouse Potassium voltage-gated channel subfamily H member 2
Monoclonal Antibody for Mouse Potassium voltage-gated channel subfamily H member 2
Monoclonal Antibody for Mouse Potassium voltage-gated channel subfamily H member 2
Monoclonal Antibody for Mouse Potassium voltage-gated channel subfamily H member 2
Monoclonal Antibody for Mouse Potassium voltage-gated channel subfamily H member 2
Protein for Mouse Potassium voltage-gated channel subfamily H member 2
Protein for Mouse Potassium voltage-gated channel subfamily H member 2
Protein for Mouse Potassium voltage-gated channel subfamily H member 2
Protein for Mouse Potassium voltage-gated channel subfamily H member 2
Protein for Mouse Potassium voltage-gated channel subfamily H member 2
Protein for Mouse Potassium voltage-gated channel subfamily H member 2
Protein for Mouse Potassium voltage-gated channel subfamily H member 2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORMS 1; 2 AND 3);VARIANTS ARG-186; THR-455; TYR-752 AND ASN-1006
strain :
129/Sv .
strain :
BALB/c .
tissue :
Heart .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 3)
tissue :
Atrial tumor .