Protein name:
Small conductance calcium-activated potassium channel protein 3 (SK3;SKCa 3;SKCa3) ;
Alternative:
KCa2.3 ;
Organism:
Pig (Sus scrofa).
General Annotation
Sub Unit:
Heterooligomer. The complex is composed of 4 channel subunits each of which binds to a calmodulin subunit which regulates the channel activity through calcium-binding.
Function:
Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin.
Subcellular Location:
Membrane
Multi-pass membrane protein
Protein Attributes:
50:
MDTSGHFHDS | GVGDLDEDPK | CPCPSSGDEQ | QQQQPPPPPP | PPAPPAAPQQ |
100:
PPGPPLQPQP | LQLQQQQQQQ | QQQPPHPLSQ | LAQLQSQPVH | PGLLHSSPTA |
150:
FRAPPSSNST | AILHPSSRQG | SQLNLNDHLL | GHSPSSTATS | GPGGGGRHRQ |
200:
ASPLVHRRDS | NPFTEIAMSS | CKYSGGVMKP | LSRLSASRRN | LIEAEPEGQP |
250:
LQLFSPSNPP | EIIISSREDN | HAHQTLLHHP | NATHNHQHAG | TTASSTTFPK |
300:
ANKRKNQNIG | YKLGHRRALF | EKRKRLSDYA | LIFGMFGIVV | MVIETELSWG |
350:
LYSKDSMFSL | ALKCLISLST | IILLGLIIAY | HTREVQLFVI | DNGADDWRIA |
400:
MTYERILYIS | LEMLVCAIHP | IPGEYKFFWT | ARLAFSYTPS | RAEADVDIIL |
450:
SIPMFLRLYL | IARVMLLHSK | LFTDASSRSI | GALNKINFNT | RFVMKTLMTI |
500:
CPGTVLLVFS | ISLWIIAAWT | VRVCERYHDQ | QDVTSNFLGA | MWLISITFLS |
550:
IGYGDMVPHT | YCGKGVCLLT | GIMGAGCTAL | VVAVVARKLE | LTKAEKHVHN |
600:
FMMDTQLTKR | IKNAAANVLR | ETWLIYKHTK | LLKKIDHAKV | RKHQRKFLQA |
650:
IHQLRSVKME | QRKLSDQANT | LVDLSKMQNV | MYDLITELND | RSEDLEKQIG |
700:
SLESKLEHLT | ASFNSLPLLI | ADTLRQQQQQ | LLSALMEARG | VSVAVGTTHT |
724:
PLSDSPIGVS | STSFPTPYTS | SSSC
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
Rat
Pig
Polyclonal Antibody for Pig SK3
Polyclonal Antibody for Pig SK3
Polyclonal Antibody for Pig SK3
Polyclonal Antibody for Pig SK3
Monoclonal Antibody for Pig SK3
Monoclonal Antibody for Pig SK3
Monoclonal Antibody for Pig SK3
Monoclonal Antibody for Pig SK3
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Coronary artery .