Protein name:
Potassium voltage-gated channel subfamily KQT member 5 ;
Alternative:
Potassium channel subunit alpha KvLQT5 ;KQT-like 5 ;Voltage-gated potassium channel subunit Kv7.5 ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Heteromultimer with KCNQ3 (By similarity). Forms homomers when expressed in Xenopus oocytes.
Function:
Probably important in the regulation of neuronal excitability. Associates with KCNQ3 to form a potassium channel which contributes to M-type current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons. May contribute, with other potassium channels, to the molecular diversity of an heterogeneous population of M-channels, varying in kinetic and pharmacological properties, which underlie this physiologically important current.
Subcellular Location:
Membrane
Multi-pass membrane protein
Protein Attributes:
50:
MPRHHAGGEE | GGAAGLWVRS | GAAAAAGAGG | GRPGSGMKDV | ESGRGRVLLN |
100:
SAAARGDGLL | LLGTRAAALG | GGGGGLRESR | RGKQGARMSL | LGKPLSYTSS |
150:
QSCRRNVKYR | RVQNYLYNVL | ERPRGWAFVY | HAFVFLLVFG | CLILSVFSTI |
200:
PEHTKLASSC | LLILEFVMIV | VFGLEFIIRI | WSAGCCCRYR | GWQGRLRFAR |
250:
KPFCVIDTIV | LIASIAVVSA | KTQGNIFATS | ALRSLRFLQI | LRMVRMDRRG |
300:
GTWKLLGSVV | YAHSKELITA | WYIGFLVLIF | SSFLVYLVEK | DANKEFSTYA |
350:
DALWWGTITL | TTIGYGDKTP | LTWLGRLLSA | GFALLGISFF | ALPAGILGSG |
400:
FALKVQEQHR | QKHFEKRRNP | AANLIQCVWR | SYAADEKSVS | IATWKPHLKA |
450:
LHTCSPTKKE | QGEASSSQKL | SFKERVRMAS | PRGQSIKSRQ | ASVGDRRSPS |
500:
TDITAEGSPT | KVQKSWSFND | RTRFRPSLRL | KSSQPKPVID | ADTALGIDDV |
550:
YDEKGCQCDV | SVEDLTPPLK | TVIRAIRIMK | FHVAKRKFKE | TLRPYDVKDV |
600:
IEQYSAGHLD | MLCRIKSLQT | RVDQILGKGQ | MTSDKKSREK | ITAEHETTDD |
650:
PSMLARVVKV | EKQVQSIESK | LDCLLDIYQQ | VLRKGSASAL | TLASFQIPPF |
700:
ECEQTSDYQS | PVDSKDLSGS | AQNSGCLTRS | ASANISRGLQ | FILTPNEFSA |
750:
QTFYALSPTM | HSQATQVPMS | QNDGSSVVAT | NNIANQISAA | PKPAAPTTLQ |
800:
IPPPLSAIKH | LSRPEPLLSN | PTGLQESISD | VTTCLVASKE | SVQFAQSNLT |
850:
KDRSLRKSFD | MGGETLLSVR | PMVPKDLGKS | LSVQNLIRST | EELNLQFSGS |
900:
ESSGSRGSQD | FYPKWRESKL | FITDEEVGAE | ETETDTFDGT | PPPAGEAAFS |
933:
SDSLRTGRSR | SSQNICKTGD | STDALSLPHV | KLN
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Mouse Potassium voltage-gated channel subfamily KQT member 5
ELISA Kit for Mouse Potassium voltage-gated channel subfamily KQT member 5
CLIA Kit for Mouse Potassium voltage-gated channel subfamily KQT member 5
CLIA Kit for Mouse Potassium voltage-gated channel subfamily KQT member 5
Polyclonal Antibody for Mouse Potassium voltage-gated channel subfamily KQT member 5
Polyclonal Antibody for Mouse Potassium voltage-gated channel subfamily KQT member 5
Monoclonal Antibody for Mouse Potassium voltage-gated channel subfamily KQT member 5
Monoclonal Antibody for Mouse Potassium voltage-gated channel subfamily KQT member 5
Protein for Mouse Potassium voltage-gated channel subfamily KQT member 5
Protein for Mouse Potassium voltage-gated channel subfamily KQT member 5
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];CHARACTERIZATION;SUBUNIT;MISCELLANEOUS
tissue :
Brain .
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"A new gene of the voltage-gated potassium channel KCNQ family, KCNQ5, is a candidate gene for retinal disorders."
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 56-933
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BALB/c .
tissue :
Brain .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 362-933
strain :
C57BL/6J .
tissue :
Brain cortex .