Protein name:
Potassium voltage-gated channel subfamily V member 1 ;
Alternative:
Voltage-gated potassium channel subunit Kv8.1 ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Heteromultimer with KCNB1 and KCNB2. Interacts with KCNC4 and KCND1.
Function:
Potassium channel subunit that does not form functional channels by itself. Modulates KCNB1 and KCNB2 channel activity by shifting the threshold for inactivation to more negative values and by slowing the rate of inactivation. Can down-regulate the channel activity of KCNB1, KCNB2, KCNC4 and KCND1, possibly by trapping them in intracellular membranes.
Subcellular Location:
Cell membrane
Multi-pass membrane protein
Has to be associated with another potassium channel subunit to get inserted in the plasma membrane. Remains intracellular in the absence of KCNB2.
Protein Attributes:
50:
MDLSPRNRPL | LDSSSLDSGS | LTSLDSSVFC | SEGEGEPLAL | GDCFTVNVGG |
100:
SRFVLSQQAL | SCFPHTRLGK | LAVVVASYRR | LGALAAAPSP | LELCDDANPV |
150:
DNEYFFDRSS | QAFRYVLHYY | RTGRLHVMEQ | LCALSFLQEI | QYWGIDELSI |
200:
DSCCRDRYFR | RKELSETLDF | KKDTDDQESQ | HESEQDFSKG | PCPTVRQKLW |
250:
DILEKPGSST | AARIFGVISI | IFVAVSIVNM | ALMSAELSWL | NLQLLEILEY |
300:
VCISWFTGEF | VLRFLCVKDR | CHFLRKVPNI | IDLLAILPFY | ITLLVESLSG |
350:
SHTTQELENV | GRLVQVLRLL | RALRMLKLGR | HSTGLRSLGM | TITQCYEEVG |
400:
LLLLFLSVGI | SIFSTIEYFA | EQSIPDTTFT | SVPCAWWWAT | TSMTTVGYGD |
450:
IRPDTTTGKI | VAFMCILSGI | LVLALPIAII | NDRFSACYFT | LKLKEAAVRQ |
500:
REALKKLTKN | IATDSYISVN | LRDVYARSIM | EMLRLKGRER | ASTRSSGGDD |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Mouse
Rat
Human
ELISA Kit for Mouse Potassium voltage-gated channel subfamily V member 1
ELISA Kit for Mouse Potassium voltage-gated channel subfamily V member 1
ELISA Kit for Mouse Potassium voltage-gated channel subfamily V member 1
ELISA Kit for Mouse Potassium voltage-gated channel subfamily V member 1
CLIA Kit for Mouse Potassium voltage-gated channel subfamily V member 1
CLIA Kit for Mouse Potassium voltage-gated channel subfamily V member 1
CLIA Kit for Mouse Potassium voltage-gated channel subfamily V member 1
CLIA Kit for Mouse Potassium voltage-gated channel subfamily V member 1
Polyclonal Antibody for Mouse Potassium voltage-gated channel subfamily V member 1
Polyclonal Antibody for Mouse Potassium voltage-gated channel subfamily V member 1
Polyclonal Antibody for Mouse Potassium voltage-gated channel subfamily V member 1
Polyclonal Antibody for Mouse Potassium voltage-gated channel subfamily V member 1
Monoclonal Antibody for Mouse Potassium voltage-gated channel subfamily V member 1
Monoclonal Antibody for Mouse Potassium voltage-gated channel subfamily V member 1
Monoclonal Antibody for Mouse Potassium voltage-gated channel subfamily V member 1
Monoclonal Antibody for Mouse Potassium voltage-gated channel subfamily V member 1
Protein for Mouse Potassium voltage-gated channel subfamily V member 1
Protein for Mouse Potassium voltage-gated channel subfamily V member 1
Protein for Mouse Potassium voltage-gated channel subfamily V member 1
Protein for Mouse Potassium voltage-gated channel subfamily V member 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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more...
Science309:1559-1563(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6J .
tissue :
Brain cortex .
tissue :
Diencephalon .
tissue :
Embryo .
tissue :
Hypothalamus .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]